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    Lrrc42 leucine rich repeat containing 42 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 298309, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Lrrc42provided by RGD
    Official Full Name
    leucine rich repeat containing 42provided by RGD
    Primary source
    RGD:1308919
    See related
    Ensembl:ENSRNOG00000009983 AllianceGenome:RGD:1308919
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1308919
    Summary
    Orthologous to human LRRC42 (leucine rich repeat containing 42). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Thymus (RPKM 247.9), Lung (RPKM 91.8) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    5q34
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (127243484..127264599, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (122014678..122035792, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (126835170..126856283, complement)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene transcription elongation factor A N-terminal and central domain containing 2 Neighboring gene transmembrane protein 59 Neighboring gene low density lipoprotein receptor class A domain containing 1 Neighboring gene intraflagellar transport 25 Neighboring gene iodothyronine deiodinase 1 Neighboring gene uncharacterized LOC134486960

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC112649

    General protein information

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    Preferred Names
    leucine-rich repeat-containing protein 42

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025653.1 → NP_001020824.1  leucine-rich repeat-containing protein 42

      See identical proteins and their annotated locations for NP_001020824.1

      Status: PROVISIONAL

      Source sequence(s)
      BC098685
      UniProtKB/Swiss-Prot
      Q4KM95
      UniProtKB/TrEMBL
      A6JYR1, A6JYR2
      Related
      ENSRNOP00000013575.4, ENSRNOT00000013575.7
      Conserved Domains (2) summary
      sd00034
      Location:150 → 174
      LRR_AMN1; leucine-rich repeat [structural motif]
      cl39015
      Location:167 → 272
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      127243484..127264599 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006238503.5 → XP_006238565.1  leucine-rich repeat-containing protein 42 isoform X1

      See identical proteins and their annotated locations for XP_006238565.1

      UniProtKB/Swiss-Prot
      Q4KM95
      UniProtKB/TrEMBL
      A6JYR1, A6JYR2
      Conserved Domains (2) summary
      sd00034
      Location:150 → 174
      LRR_AMN1; leucine-rich repeat [structural motif]
      cl39015
      Location:167 → 272
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    2. XM_039109553.2 → XP_038965481.1  leucine-rich repeat-containing protein 42 isoform X1

      UniProtKB/Swiss-Prot
      Q4KM95
      UniProtKB/TrEMBL
      A6JYR1, A6JYR2
      Conserved Domains (2) summary
      sd00034
      Location:150 → 174
      LRR_AMN1; leucine-rich repeat [structural motif]
      cl39015
      Location:167 → 272
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q4KM95.1 GenPept UniProtKB/Swiss-Prot:Q4KM95

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