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    Secisbp2l SECIS binding protein 2-like [ Rattus norvegicus (Norway rat) ]

    Gene ID: 296115, updated on 30-Mar-2024

    Summary

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    Official Symbol
    Secisbp2lprovided by RGD
    Official Full Name
    SECIS binding protein 2-likeprovided by RGD
    Primary source
    RGD:1559930
    See related
    Ensembl:ENSRNOG00000008629 AllianceGenome:RGD:1559930
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1559930
    Summary
    Predicted to enable mRNA 3'-UTR binding activity; ribonucleoprotein complex binding activity; and selenocysteine insertion sequence binding activity. Predicted to be involved in selenocysteine incorporation. Predicted to be part of ribonucleoprotein complex. Orthologous to human SECISBP2L (SECIS binding protein 2 like). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Brain (RPKM 262.5), Lung (RPKM 187.1) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    3q36
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (133443023..133489467, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (112989613..113036060, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (118007950..118051403, complement)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene 40S ribosomal protein S14-like Neighboring gene centrosomal protein 152 Neighboring gene SHC adaptor protein 4 Neighboring gene EP300 interacting inhibitor of differentiation 1 Neighboring gene TATA element modulatory factor 1, pseudogene 1 Neighboring gene COP9 signalosome subunit 2 Neighboring gene galactokinase 2 Neighboring gene family with sequence similarity 227, member B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Sequential Elution Interactome Analysis of the Mind Bomb 1 Ubiquitin Ligase Reveals a Novel Role in Dendritic Spine Outgrowth. Mertz J, et al. Mol Cell Proteomics, 2015 Jul. PMID 25931508, Free PMC Article
    2. The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Baltz AG, et al. Mol Cell, 2012 Jun 8. PMID 22681889
    3. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Castello A, et al. Cell, 2012 Jun 8. PMID 22658674
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables mRNA 3'-UTR binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ribonucleoprotein complex binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables selenocysteine insertion sequence binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in selenocysteine incorporation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of ribonucleoprotein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    selenocysteine insertion sequence-binding protein 2-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001168527.1 → NP_001161999.1  selenocysteine insertion sequence-binding protein 2-like

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003
      UniProtKB/TrEMBL
      A0A8I6GIQ2
      Related
      ENSRNOP00000090224.1, ENSRNOT00000120193.1
      Conserved Domains (1) summary
      pfam01248
      Location:700 → 802
      Ribosomal_L7Ae; Ribosomal protein L7Ae/L30e/S12e/Gadd45 family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      133443023..133489467 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039104555.2 → XP_038960483.1  selenocysteine insertion sequence-binding protein 2-like isoform X1

      UniProtKB/TrEMBL
      A0A8I6GIQ2, D4A7V0
      Related
      ENSRNOP00000011551.6
      Conserved Domains (1) summary
      pfam01248
      Location:704 → 806
      Ribosomal_L7Ae; Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
    Nucleotide Protein Strain
    Heading Accession and Version

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