U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    FDFT1 farnesyl-diphosphate farnesyltransferase 1 [ Bos taurus (cattle) ]

    Gene ID: 281767, updated on 5-Mar-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    FDFT1provided by VGNC
    Official Full Name
    farnesyl-diphosphate farnesyltransferase 1provided by VGNC
    Primary source
    VGNC:VGNC:56966
    See related
    BGD:BT11645; Ensembl:ENSBTAG00000012432
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Location:
    chromosome: 8
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 8 NC_037335.1 (7591013..7617467, complement)

    Chromosome 8 - NC_037335.1Genomic Context describing neighboring genes Neighboring gene defensin beta 136 Neighboring gene cathepsin B Neighboring gene nei like DNA glycosylase 2 Neighboring gene GATA binding protein 4

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_037335.1 Chromosome 8 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Clone Names

    • MGC134482

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables farnesyl-diphosphate farnesyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables squalene synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cholesterol biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in farnesyl diphosphate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    squalene synthase
    Names
    FPP:FPP farnesyltransferase
    SQS
    SS
    squalene synthetase
    NP_001013022.1
    XP_010805999.1
    XP_010806000.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013004.1 → NP_001013022.1  squalene synthase

      See identical proteins and their annotated locations for NP_001013022.1

      Status: PROVISIONAL

      Source sequence(s)
      BN000317
      UniProtKB/Swiss-Prot
      Q32KR6
      UniProtKB/TrEMBL
      F1MW61, Q6IE76
      Related
      ENSBTAP00000016504.5, ENSBTAT00000016504.7
      Conserved Domains (1) summary
      cl00210
      Location:38 → 370
      Isoprenoid_Biosyn_C1; Isoprenoid Biosynthesis enzymes, Class 1

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037335.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      7591013..7617467 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_010807698.3 → XP_010806000.1  squalene synthase isoform X2

      Conserved Domains (1) summary
      cl00210
      Location:18 → 276
      Isoprenoid_Biosyn_C1; Isoprenoid Biosynthesis enzymes, Class 1

    2. XM_010807697.4 → XP_010805999.1  squalene synthase isoform X1

      UniProtKB/Swiss-Prot
      Q32KR6
      Related
      ENSBTAP00000102509.1, ENSBTAT00000099158.1
      Conserved Domains (1) summary
      cl00210
      Location:92 → 424
      Isoprenoid_Biosyn_C1; Isoprenoid Biosynthesis enzymes, Class 1
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q32KR6.1 GenPept UniProtKB/Swiss-Prot:Q32KR6

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Miscellaneous