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    galla-1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 246485, updated on 11-Apr-2024

    Summary

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    Official Symbol
    galla-1provided by FlyBase
    Primary source
    FLYBASE:FBgn0034543
    Locus tag
    Dmel_CG30152
    See related
    AllianceGenome:FB:FBgn0034543
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG10404; Cg30152; CG30152; Dmel\CG30152; FAM96a; Galla-1; galla1; Galla1
    Summary
    Involved in nuclear chromosome segregation. Located in spindle microtubule. Is expressed in embryonic/larval central nervous system; embryonic/larval fat body; eye disc; and larval ventral nerve cord. Orthologous to human CIAO2A (cytosolic iron-sulfur assembly component 2A). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    Location:
    57A10-57A10; 2-91 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (20670636..20673495)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (16558141..16561000)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Leucine-rich tendon-specific protein Neighboring gene transfer RNA:Tryptophan-CCA 1-2 Neighboring gene uncharacterized protein Neighboring gene Fem-1 Neighboring gene exuperantia Neighboring gene Gustatory receptor 57a Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Accumulation of Spock and Worf, two novel non-LTR retrotransposons, on the neo-Y chromosome of Drosophila miranda. Bachtrog D. Mol Biol Evol, 2003 Feb. PMID 12598683
    2. Crumbs interacts with Xpd for nuclear division control in Drosophila. Yeom E, et al. Oncogene, 2015 May 21. PMID 25065591
    3. Ciao1 interacts with Crumbs and Xpd to regulate organ growth in Drosophila. Jung J, et al. Cell Death Dis, 2020 May 13. PMID 32404863, Free PMC Article
    4. On the genomic location of the exuperantia1 gene in Drosophila miranda: the limits of in situ hybridization experiments. Bachtrog D, et al. Genetics, 2003 Jul. PMID 12871928, Free PMC Article
    5. Crumbs, Galla and Xpd are required for Kinesin-5 regulation in mitosis and organ growth in Drosophila. Hwang JH, et al. J Cell Sci, 2020 Jun 23. PMID 32501288

    See all (39) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in nuclear chromosome segregation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein maturation by [4Fe-4S] cluster transfer IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein maturation by iron-sulfur cluster transfer IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in spindle microtubule IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    galla-1
    Names
    CG30152-PA
    CG30152-PB
    CG30152-PC
    CG30152-PD
    galla-1-PA
    galla-1-PB
    galla-1-PC
    galla-1-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      20670636..20673495
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001299714.1 → NP_001286643.1  galla-1, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286643.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9V968
      UniProtKB/TrEMBL
      A0A0B4LG04
      Conserved Domains (1) summary
      cl00941
      Location:94 → 214
      DUF59; Domain of unknown function DUF59

    2. NM_001299713.1 → NP_001286642.1  galla-1, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286642.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9V968
      UniProtKB/TrEMBL
      A0A0B4LG04
      Conserved Domains (1) summary
      cl00941
      Location:94 → 214
      DUF59; Domain of unknown function DUF59

    3. NM_137665.2 → NP_611509.1  galla-1, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611509.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9V968
      UniProtKB/TrEMBL
      A0A0B4LG04
      Related
      FBpp0085549
      Conserved Domains (1) summary
      cl00941
      Location:94 → 214
      DUF59; Domain of unknown function DUF59

    4. NM_001299715.1 → NP_001286644.1  galla-1, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286644.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LH12
      Conserved Domains (1) summary
      cl00941
      Location:28 → 148
      DUF59; Domain of unknown function DUF59
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4LG04 A0A0B4LG04
    A0A0B4LH12 A0A0B4LH12
    Q9V968.1 Q9V968

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