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    txdc-9 Thioredoxin domain-containing protein 9 [ Caenorhabditis elegans ]

    Gene ID: 182257, updated on 23-Nov-2023

    Summary

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    Gene symbol
    txdc-9
    Gene description
    Thioredoxin domain-containing protein 9
    Primary source
    WormBase:WBGene00006515
    Locus tag
    CELE_C05D11.3
    See related
    AllianceGenome:WB:WBGene00006515
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in microtubule cytoskeleton organization. Located in cytoplasm and nucleus. Is expressed in nervous system; pharynx; and vulva. Orthologous to human TXNDC9 (thioredoxin domain containing 9). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    Location:
    chromosome: III
    Exon count:
    3
    Sequence:
    Chromosome: III; NC_003281.10 (6432178..6433145)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Ribonucleases P/MRP protein subunit popl-1 Neighboring gene Small ribosomal subunit protein uS17m Neighboring gene Vacuolar protein sorting-associated protein 16 homolog Neighboring gene Uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. An evolutionarily conserved gene required for proper microtubule architecture in Caenorhabditis elegans. Ogawa S, et al. Genes Cells, 2004 Feb. PMID 15009089
    2. Lysosome biogenesis mediated by vps-18 affects apoptotic cell degradation in Caenorhabditis elegans. Xiao H, et al. Mol Biol Cell, 2009 Jan. PMID 18923146, Free PMC Article
    3. Caenorhabditis elegans SAND-1 is essential for RAB-7 function in endosomal traffic. Poteryaev D, et al. EMBO J, 2007 Jan 24. PMID 17203072, Free PMC Article
    4. Identification of nonviable genes affecting touch sensitivity in Caenorhabditis elegans using neuronally enhanced feeding RNA interference. Chen X, et al. G3 (Bethesda), 2015 Jan 9. PMID 25575561, Free PMC Article
    5. Genetic analysis of lysosomal trafficking in Caenorhabditis elegans. Hermann GJ, et al. Mol Biol Cell, 2005 Jul. PMID 15843430, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in microtubule cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in microtubule cytoskeleton organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Thioredoxin domain-containing protein 9
    NP_498410.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      6432178..6433145
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_066009.5 → NP_498410.1  Thioredoxin domain-containing protein 9 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_498410.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q11183
      Conserved Domains (1) summary
      cd02989
      Location:63 → 175
      Phd_like_TxnDC9; Phosducin (Phd)-like family, Thioredoxin (TRX) domain containing protein 9 (TxnDC9) subfamily; composed of predominantly uncharacterized eukaryotic proteins, containing a TRX-like domain without the redox active CXXC motif. The gene name for the human ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q11183.1

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