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    mfsd-10 Major facilitator superfamily (MFS) profile domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 181765, updated on 23-Nov-2023

    Summary

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    Gene symbol
    mfsd-10
    Gene description
    Major facilitator superfamily (MFS) profile domain-containing protein
    Primary source
    WormBase:WBGene00017339
    Locus tag
    CELE_F10D7.2
    See related
    AllianceGenome:WB:WBGene00017339
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in brush border membrane. Is expressed in head; hypodermis; and pharynx. Orthologous to human MFSD10 (major facilitator superfamily domain containing 10). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    Location:
    chromosome: X
    Exon count:
    12
    Sequence:
    Chromosome: X; NC_003284.9 (17364707..17368642, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ETS domain-containing protein Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein Neighboring gene DUF148 domain-containing protein Neighboring gene ncRNA Neighboring gene putative monothiol glutaredoxin F10D7.3 Neighboring gene CB1 cannabinoid receptor-interacting protein 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    2. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in brush border membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Major facilitator superfamily (MFS) profile domain-containing protein
    NP_510814.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      17364707..17368642 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_078413.6 → NP_510814.1  Major facilitator superfamily (MFS) profile domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_510814.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q19296
      Conserved Domains (1) summary
      cl28910
      Location:19 → 423
      MFS; Major Facilitator Superfamily
    Nucleotide Protein
    Heading Accession and Version

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