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    zbtb38 zinc finger and BTB domain containing 38 [ Danio rerio (zebrafish) ]

    Gene ID: 101882192, updated on 27-Mar-2024

    Summary

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    Official Symbol
    zbtb38provided by ZNC
    Official Full Name
    zinc finger and BTB domain containing 38provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-091204-308
    See related
    Ensembl:ENSDARG00000100607 AllianceGenome:ZFIN:ZDB-GENE-091204-308
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:ch73-160p19.2
    Summary
    Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleoplasm. Orthologous to human ZBTB38 (zinc finger and BTB domain containing 38). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    Location:
    chromosome: 18
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (41197827..41219784, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (41207373..41229640, complement)

    Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene transmembrane protein 255B Neighboring gene RAS p21 protein activator 2 Neighboring gene F-box protein 36a Neighboring gene thyroid hormone receptor interactor 12

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    2. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Sex-specific DNA methylation and transcription of zbtb38 and effects of gene-environment interactions on its natural antisense transcript in zebrafish.
      Title: Sex-specific DNA methylation and transcription of zbtb38 and effects of gene-environment interactions on its natural antisense transcript in zebrafish.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables DNA-binding transcription repressor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of cytokine production IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of immune system process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger and BTB domain-containing protein 38

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007129.7 Reference GRCz11 Primary Assembly

      Range
      41197827..41219784 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009293815.3 → XP_009292090.1  zinc finger and BTB domain-containing protein 38 isoform X1

      See identical proteins and their annotated locations for XP_009292090.1

      UniProtKB/TrEMBL
      A0A0R4IVZ9, A0A8M3AKL6
      Related
      ENSDARP00000140537.1, ENSDART00000162387.2
      Conserved Domains (3) summary
      smart00225
      Location:75 → 171
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00017
      Location:524 → 544
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00651
      Location:64 → 163
      BTB; BTB/POZ domain

    2. XM_009293816.3 → XP_009292091.1  zinc finger and BTB domain-containing protein 38 isoform X1

      See identical proteins and their annotated locations for XP_009292091.1

      UniProtKB/TrEMBL
      A0A0R4IVZ9, A0A8M3AKL6
      Related
      ENSDARP00000149140.1, ENSDART00000193753.1
      Conserved Domains (3) summary
      smart00225
      Location:75 → 171
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00017
      Location:524 → 544
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00651
      Location:64 → 163
      BTB; BTB/POZ domain

    3. XM_017352120.2 → XP_017207609.1  zinc finger and BTB domain-containing protein 38 isoform X2

      UniProtKB/TrEMBL
      A0A8M3AS58
      Conserved Domains (3) summary
      smart00225
      Location:35 → 131
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00017
      Location:484 → 504
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00651
      Location:24 → 123
      BTB; BTB/POZ domain

    4. XM_009293819.3 → XP_009292094.1  zinc finger and BTB domain-containing protein 38 isoform X2

      See identical proteins and their annotated locations for XP_009292094.1

      UniProtKB/TrEMBL
      A0A8M3AS58
      Conserved Domains (3) summary
      smart00225
      Location:35 → 131
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00017
      Location:484 → 504
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00651
      Location:24 → 123
      BTB; BTB/POZ domain

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018395046.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      4..20380 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021473344.1 → XP_021329019.1  zinc finger and BTB domain-containing protein 38 isoform X3

      UniProtKB/TrEMBL
      A0A8M9PW17
      Conserved Domains (4) summary
      sd00017
      Location:524 → 544
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:396 → 418
      zf-C2H2; Zinc finger, C2H2 type
      pfam00651
      Location:64 → 163
      BTB; BTB/POZ domain
      pfam13465
      Location:567 → 589
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein
    Heading Accession and Version

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