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    DEFB125 defensin beta 125 [ Canis lupus familiaris (dog) ]

    Gene ID: 100683603, updated on 8-Mar-2024

    Summary

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    Official Symbol
    DEFB125provided by VGNC
    Official Full Name
    defensin beta 125provided by VGNC
    Primary source
    VGNC:VGNC:39879
    See related
    Ensembl:ENSCAFG00845017637
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Also known as
    CBD125
    Orthologs
    human mouse all
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    Genomic context

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    See DEFB125 in Genome Data Viewer
    Location:
    chromosome: 24
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 24 NC_051828.1 (21431588..21445845, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 24 NC_006606.4 (20390886..20404939, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 24 NC_049245.1 (21243559..21257625, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 24 NC_049284.1 (20707797..20721860, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 24 NC_049765.1 (20812951..20826998, complement)

    Chromosome 24 - NC_051828.1Genomic Context describing neighboring genes Neighboring gene defensin beta 127 Neighboring gene defensin beta 126 Neighboring gene U6 spliceosomal RNA Neighboring gene E3 ubiquitin-protein ligase RNF14-like Neighboring gene defensin beta 116

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract. Patil AA, et al. Physiol Genomics, 2005 Sep 21. PMID 16033865

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in innate immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    beta-defensin 125

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051828.1 Reference ROS_Cfam_1.0

      Range
      21431588..21445845 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038433412.1 → XP_038289340.1  beta-defensin 125

      UniProtKB/TrEMBL
      A0A8C0JTC6, A0A8C0TD24, Q30KS9
      Related
      ENSCAFP00845024440.1, ENSCAFT00845031220.1
      Conserved Domains (1) summary
      pfam13841
      Location:26 → 56
      Defensin_beta_2; Beta defensin

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049284.1 Alternate UMICH_Zoey_3.1

      Range
      20707797..20721860 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038508616.1 → XP_038364544.1  beta-defensin 125

      Conserved Domains (1) summary
      pfam13841
      Location:26 → 56
      Defensin_beta_2; Beta defensin

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049765.1 Alternate UNSW_CanFamBas_1.0

      Range
      20812951..20826998 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038636160.1 → XP_038492088.1  beta-defensin 125

      Conserved Domains (1) summary
      pfam13841
      Location:26 → 56
      Defensin_beta_2; Beta defensin

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049245.1 Alternate UU_Cfam_GSD_1.0

      Range
      21243559..21257625 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038571906.1 → XP_038427834.1  beta-defensin 125

      UniProtKB/TrEMBL
      A0A8C0JTC6, A0A8C0TD24, Q30KS9
      Conserved Domains (1) summary
      pfam13841
      Location:26 → 56
      Defensin_beta_2; Beta defensin

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006606.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      20390886..20404939 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003433236.3 → XP_003433284.1  beta-defensin 125

      See identical proteins and their annotated locations for XP_003433284.1

      UniProtKB/TrEMBL
      A0A8C0JTC6, A0A8C0TD24, Q30KS9
      Conserved Domains (1) summary
      pfam13841
      Location:26 → 56
      Defensin_beta_2; Beta defensin
    Nucleotide Protein
    Heading Accession and Version

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