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    GRM3 glutamate metabotropic receptor 3 [ Canis lupus familiaris (dog) ]

    Gene ID: 100683236, updated on 8-Mar-2024

    Summary

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    Official Symbol
    GRM3provided by VGNC
    Official Full Name
    glutamate metabotropic receptor 3provided by VGNC
    Primary source
    VGNC:VGNC:41510
    See related
    Ensembl:ENSCAFG00845006684
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See GRM3 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 14 NC_051818.1 (12622206..12831301)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 14 NC_006596.4 (12495006..12703930)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 14 NC_049235.1 (12836839..13046196)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 14 NC_049274.1 (12827178..13036385)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 14 NC_049755.1 (12553520..12762200)

    Chromosome 14 - NC_051818.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111098738 Neighboring gene zinc finger protein 300-like Neighboring gene transmembrane protein 138-like Neighboring gene endosome-lysosome associated apoptosis and autophagy regulator family member 2 Neighboring gene elongation factor 1-alpha 1-like Neighboring gene hsc70-interacting protein-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables group II metabotropic glutamate receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled glutamate receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of synaptic transmission, glutamatergic IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    metabotropic glutamate receptor 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051818.1 Reference ROS_Cfam_1.0

      Range
      12622206..12831301
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038686284.1 → XP_038542212.1  metabotropic glutamate receptor 3 isoform X1

      UniProtKB/TrEMBL
      A0A8C0L7I7, A0A8C0S869, A0A8I3MYJ9, A0A8I3N207, A0A8P0PN98
      Related
      ENSCAFP00845009280.1, ENSCAFT00845011896.1
      Conserved Domains (3) summary
      cd15448
      Location:575 → 828
      7tmC_mGluR3; metabotropic glutamate receptor 3 in group 2, member of the class C family of seven-transmembrane G protein-coupled receptors
      cd06375
      Location:33 → 494
      PBP1_mGluR_groupII; ligand binding domain of the group II metabotropic glutamate receptor
      pfam07562
      Location:505 → 555
      NCD3G; Nine Cysteines Domain of family 3 GPCR

    2. XM_038686286.1 → XP_038542214.1  metabotropic glutamate receptor 3 isoform X3

      UniProtKB/TrEMBL
      A0A8I3RTH8, A0A8P0NP29
      Conserved Domains (3) summary
      cd15448
      Location:375 → 628
      7tmC_mGluR3; metabotropic glutamate receptor 3 in group 2, member of the class C family of seven-transmembrane G protein-coupled receptors
      pfam07562
      Location:305 → 355
      NCD3G; Nine Cysteines Domain of family 3 GPCR
      cl10011
      Location:1 → 294
      Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily

    3. XM_038686285.1 → XP_038542213.1  metabotropic glutamate receptor 3 isoform X2

      UniProtKB/TrEMBL
      A0A8I3RTH8, A0A8P0NP29
      Conserved Domains (3) summary
      cd15448
      Location:428 → 681
      7tmC_mGluR3; metabotropic glutamate receptor 3 in group 2, member of the class C family of seven-transmembrane G protein-coupled receptors
      pfam07562
      Location:358 → 408
      NCD3G; Nine Cysteines Domain of family 3 GPCR
      cl10011
      Location:9 → 347
      Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049274.1 Alternate UMICH_Zoey_3.1

      Range
      12827178..13036385
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038494366.1 → XP_038350294.1  metabotropic glutamate receptor 3 isoform X1

      Conserved Domains (3) summary
      cd15448
      Location:575 → 828
      7tmC_mGluR3; metabotropic glutamate receptor 3 in group 2, member of the class C family of seven-transmembrane G protein-coupled receptors
      cd06375
      Location:33 → 494
      PBP1_mGluR_groupII; ligand binding domain of the group II metabotropic glutamate receptor
      pfam07562
      Location:505 → 555
      NCD3G; Nine Cysteines Domain of family 3 GPCR

    2. XM_038494368.1 → XP_038350296.1  metabotropic glutamate receptor 3 isoform X3

      Conserved Domains (3) summary
      cd15448
      Location:375 → 628
      7tmC_mGluR3; metabotropic glutamate receptor 3 in group 2, member of the class C family of seven-transmembrane G protein-coupled receptors
      pfam07562
      Location:305 → 355
      NCD3G; Nine Cysteines Domain of family 3 GPCR
      cl10011
      Location:1 → 294
      Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily

    3. XM_038494367.1 → XP_038350295.1  metabotropic glutamate receptor 3 isoform X2

      Conserved Domains (3) summary
      cd15448
      Location:428 → 681
      7tmC_mGluR3; metabotropic glutamate receptor 3 in group 2, member of the class C family of seven-transmembrane G protein-coupled receptors
      pfam07562
      Location:358 → 408
      NCD3G; Nine Cysteines Domain of family 3 GPCR
      cl10011
      Location:9 → 347
      Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049755.1 Alternate UNSW_CanFamBas_1.0

      Range
      12553520..12762200
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038620595.1 → XP_038476523.1  metabotropic glutamate receptor 3 isoform X1

      Conserved Domains (3) summary
      cd15448
      Location:575 → 828
      7tmC_mGluR3; metabotropic glutamate receptor 3 in group 2, member of the class C family of seven-transmembrane G protein-coupled receptors
      cd06375
      Location:33 → 494
      PBP1_mGluR_groupII; ligand binding domain of the group II metabotropic glutamate receptor
      pfam07562
      Location:505 → 555
      NCD3G; Nine Cysteines Domain of family 3 GPCR

    2. XM_038620597.1 → XP_038476525.1  metabotropic glutamate receptor 3 isoform X3

      Conserved Domains (3) summary
      cd15448
      Location:375 → 628
      7tmC_mGluR3; metabotropic glutamate receptor 3 in group 2, member of the class C family of seven-transmembrane G protein-coupled receptors
      pfam07562
      Location:305 → 355
      NCD3G; Nine Cysteines Domain of family 3 GPCR
      cl10011
      Location:1 → 294
      Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily

    3. XM_038620596.1 → XP_038476524.1  metabotropic glutamate receptor 3 isoform X2

      Conserved Domains (3) summary
      cd15448
      Location:428 → 681
      7tmC_mGluR3; metabotropic glutamate receptor 3 in group 2, member of the class C family of seven-transmembrane G protein-coupled receptors
      pfam07562
      Location:358 → 408
      NCD3G; Nine Cysteines Domain of family 3 GPCR
      cl10011
      Location:9 → 347
      Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049235.1 Alternate UU_Cfam_GSD_1.0

      Range
      12836839..13046196
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038556665.1 → XP_038412593.1  metabotropic glutamate receptor 3 isoform X1

      UniProtKB/TrEMBL
      A0A8C0L7I7, A0A8C0S869, A0A8I3MYJ9, A0A8I3N207, A0A8P0PN98
      Conserved Domains (3) summary
      cd15448
      Location:575 → 828
      7tmC_mGluR3; metabotropic glutamate receptor 3 in group 2, member of the class C family of seven-transmembrane G protein-coupled receptors
      cd06375
      Location:33 → 494
      PBP1_mGluR_groupII; ligand binding domain of the group II metabotropic glutamate receptor
      pfam07562
      Location:505 → 555
      NCD3G; Nine Cysteines Domain of family 3 GPCR

    2. XM_038556667.1 → XP_038412595.1  metabotropic glutamate receptor 3 isoform X3

      UniProtKB/TrEMBL
      A0A8I3RTH8, A0A8P0NP29
      Conserved Domains (3) summary
      cd15448
      Location:375 → 628
      7tmC_mGluR3; metabotropic glutamate receptor 3 in group 2, member of the class C family of seven-transmembrane G protein-coupled receptors
      pfam07562
      Location:305 → 355
      NCD3G; Nine Cysteines Domain of family 3 GPCR
      cl10011
      Location:1 → 294
      Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily

    3. XM_038556666.1 → XP_038412594.1  metabotropic glutamate receptor 3 isoform X2

      UniProtKB/TrEMBL
      A0A8I3RTH8, A0A8P0NP29
      Conserved Domains (3) summary
      cd15448
      Location:428 → 681
      7tmC_mGluR3; metabotropic glutamate receptor 3 in group 2, member of the class C family of seven-transmembrane G protein-coupled receptors
      pfam07562
      Location:358 → 408
      NCD3G; Nine Cysteines Domain of family 3 GPCR
      cl10011
      Location:9 → 347
      Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006596.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      12495006..12703930
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_022427284.2 → XP_022282992.2  metabotropic glutamate receptor 3 isoform X1

      UniProtKB/TrEMBL
      A0A8C0L7I7, A0A8C0S869, A0A8I3MYJ9, A0A8I3N207, A0A8P0PN98
      Conserved Domains (3) summary
      cd15448
      Location:575 → 828
      7tmC_mGluR3; metabotropic glutamate receptor 3 in group 2, member of the class C family of seven-transmembrane G protein-coupled receptors
      cd06375
      Location:33 → 494
      PBP1_mGluR_groupII; ligand binding domain of the group II metabotropic glutamate receptor
      pfam07562
      Location:505 → 555
      NCD3G; Nine Cysteines Domain of family 3 GPCR

    2. XM_038443806.1 → XP_038299734.1  metabotropic glutamate receptor 3 isoform X3

      UniProtKB/TrEMBL
      A0A8I3RTH8, A0A8P0NP29
      Conserved Domains (3) summary
      cd15448
      Location:375 → 628
      7tmC_mGluR3; metabotropic glutamate receptor 3 in group 2, member of the class C family of seven-transmembrane G protein-coupled receptors
      pfam07562
      Location:305 → 355
      NCD3G; Nine Cysteines Domain of family 3 GPCR
      cl10011
      Location:1 → 294
      Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily

    3. XM_038443802.1 → XP_038299730.1  metabotropic glutamate receptor 3 isoform X2

      UniProtKB/TrEMBL
      A0A8I3RTH8, A0A8P0NP29
      Conserved Domains (3) summary
      cd15448
      Location:428 → 681
      7tmC_mGluR3; metabotropic glutamate receptor 3 in group 2, member of the class C family of seven-transmembrane G protein-coupled receptors
      pfam07562
      Location:358 → 408
      NCD3G; Nine Cysteines Domain of family 3 GPCR
      cl10011
      Location:9 → 347
      Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily
    Nucleotide Protein
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