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    Tmppe transmembrane protein with metallophosphoesterase domain [ Mus musculus (house mouse) ]

    Gene ID: 100504715, updated on 8-Mar-2024

    Summary

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    Official Symbol
    Tmppeprovided by MGI
    Official Full Name
    transmembrane protein with metallophosphoesterase domainprovided by MGI
    Primary source
    MGI:MGI:5317335
    See related
    Ensembl:ENSMUSG00000079260 AllianceGenome:MGI:5317335
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Orthologous to human TMPPE (transmembrane protein with metallophosphoesterase domain). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in thymus adult (RPKM 7.5), kidney adult (RPKM 7.4) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    9 F3; 9 64.4 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (114230163..114240269)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (114401095..114411201)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930525D18 gene Neighboring gene RIKEN cDNA 4930520O04 gene Neighboring gene cartilage associated protein Neighboring gene STARR-seq mESC enhancer starr_25345 Neighboring gene STARR-seq mESC enhancer starr_25346 Neighboring gene STARR-positive B cell enhancer ABC_E5109 Neighboring gene STARR-positive B cell enhancer mm9_chr9:114327339-114327639 Neighboring gene galactosidase, beta 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr9:114345054-114345237 Neighboring gene CapStarr-seq enhancer MGSCv37_chr9:114352487-114352773 Neighboring gene predicted gene, 30254 Neighboring gene STARR-seq mESC enhancer starr_25350 Neighboring gene C-C motif chemokine receptor 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Transcriptome analysis of mouse stem cells and early embryos. Sharov AA, et al. PLoS Biol, 2003 Dec. PMID 14691545, Free PMC Article
    2. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    transmembrane protein with metallophosphoesterase domain
    NP_001186931.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001200002.1 → NP_001186931.1  transmembrane protein with metallophosphoesterase domain

      Status: VALIDATED

      Source sequence(s)
      AC156499, AK046107, BE956926, CN705942
      Consensus CDS
      CCDS52951.1
      UniProtKB/TrEMBL
      D3Z286
      Related
      ENSMUSP00000107451.3, ENSMUST00000111820.4
      Conserved Domains (2) summary
      cd07385
      Location:206 → 443
      MPP_YkuE_C; Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain
      pfam00149
      Location:207 → 387
      Metallophos; Calcineurin-like phosphoesterase

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      114230163..114240269
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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