tmem163b transmembrane protein 163b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: tmem163bprovided by ZNC
Official Full Name: transmembrane protein 163bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-091204-410
See related: Ensembl:ENSDARG00000088227 AllianceGenome:ZFIN:ZDB-GENE-091204-410
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: si:ch73-125n14.1
Summary: Predicted to enable zinc ion binding activity. Predicted to act upstream of or within transmembrane transport and zinc ion transport. Predicted to be located in early endosome membrane and synapse. Predicted to be integral component of membrane. Predicted to be active in membrane. Predicted to be integral component of synaptic vesicle membrane. Orthologous to human TMEM163 (transmembrane protein 163). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 22

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	22	NC_007133.7 (12094428..12160512, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	22	NC_007133.6 (12064408..12130834, complement)

Chromosome 22 - NC_007133.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables zinc ion binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within myelination	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within oligodendrocyte development	IGI Inferred from Genetic Interaction more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasmic vesicle	IEA Inferred from Electronic Annotation more info
located_in early endosome membrane	IEA Inferred from Electronic Annotation more info
located_in endosome	IEA Inferred from Electronic Annotation more info
located_in late endosome membrane	IEA Inferred from Electronic Annotation more info
located_in lysosomal membrane	IEA Inferred from Electronic Annotation more info
located_in lysosome	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info
located_in synapse	IEA Inferred from Electronic Annotation more info
is_active_in synaptic vesicle membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in synaptic vesicle membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: transmembrane protein 163-like; transmembrane protein 163b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001423848.1 → NP_001410777.1 transmembrane protein 163b

Status: VALIDATED

Source sequence(s)

CU571316

UniProtKB/Swiss-Prot

A0A8M2BLF0, F2Z4R5

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007133.7 Reference GRCz11 Primary Assembly

Range

12094428..12160512 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005174011.4 → XP_005174068.1 transmembrane protein 163-like isoform X1

UniProtKB/TrEMBL

F2Z4R5

Related

ENSDARP00000122494.1, ENSDART00000146785.3

Conserved Domains (1) summary

pfam01545
Location:96 → 235

Cation_efflux; Cation efflux family
XM_002666219.6 → XP_002666265.2 transmembrane protein 163-like isoform X2

UniProtKB/TrEMBL

A0A0R4IQD0, A0A8M1RMP0

Related

ENSDARP00000136312.1, ENSDART00000158398.2

Conserved Domains (1) summary

pfam01545
Location:95 → 234

Cation_efflux; Cation efflux family