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    cbll1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 100170461, updated on 8-Mar-2024

    Summary

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    Official Symbol
    cbll1provided by Xenbase
    Official Full Name
    Cbl proto-oncogene-like 1, E3 ubiquitin protein ligaseprovided by Xenbase
    Primary source
    Xenbase:XB-GENE-6458353
    See related
    Ensembl:ENSXETG00000012262
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Also known as
    hakai; rnf188
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 3
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 3 NC_030679.2 (76283360..76294478, complement)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 3 NC_030679.1 (66649601..66660982, complement)

    Chromosome 3 - NC_030679.2Genomic Context describing neighboring genes Neighboring gene chloride anion exchanger Neighboring gene solute carrier family 26 member 3 gene 3 Neighboring gene solute carrier family 26 member 4 gene 3 Neighboring gene solute carrier family 26 member 4 gene 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase Hakai
    Names
    Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1
    Cbl proto-oncogene, E3 ubiquitin protein ligase-like 1
    NP_001123714.1
    XP_012814103.2
    XP_012814104.2
    XP_012814105.2
    XP_017947440.2
    XP_017947441.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001130242.1 → NP_001123714.1  E3 ubiquitin-protein ligase Hakai

      See identical proteins and their annotated locations for NP_001123714.1

      Status: PROVISIONAL

      Source sequence(s)
      BC167325
      UniProtKB/TrEMBL
      A0A6I8RYM5, B3DL63
      Related
      ENSXETP00000106554.1, ENSXETT00000106908.1
      Conserved Domains (1) summary
      pfam13923
      Location:105 → 142
      zf-C3HC4_2; Zinc finger, C3HC4 type (RING finger)

    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030679.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      76283360..76294478 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_018091952.2 → XP_017947441.2  E3 ubiquitin-protein ligase Hakai isoform X5

      UniProtKB/TrEMBL
      A0A6I8QTP9, A0A8J0SRY1
      Related
      ENSXETP00000072564.2, ENSXETT00000069368.2
      Conserved Domains (2) summary
      cd16508
      Location:106 → 147
      RING-HC_HAKAI_like; RING finger, HC subclass, found in E3 ubiquitin-protein ligase Hakai, zinc finger protein 645 (ZNF645), and similar proteins
      pfam18408
      Location:160 → 191
      zf_Hakai; C2H2 Hakai zinc finger domain

    2. XM_018091951.2 → XP_017947440.2  E3 ubiquitin-protein ligase Hakai isoform X4

      UniProtKB/TrEMBL
      A0A6I8QTP9, A0A6I8SBF4
      Related
      ENSXETP00000094262.2, ENSXETT00000079746.2
      Conserved Domains (2) summary
      cd16508
      Location:107 → 148
      RING-HC_HAKAI_like; RING finger, HC subclass, found in E3 ubiquitin-protein ligase Hakai, zinc finger protein 645 (ZNF645), and similar proteins
      pfam18408
      Location:161 → 192
      zf_Hakai; C2H2 Hakai zinc finger domain

    3. XM_012958650.3 → XP_012814104.2  E3 ubiquitin-protein ligase Hakai isoform X2

      UniProtKB/TrEMBL
      A0A6I8RYM5, A0A8J0SGP3
      Conserved Domains (2) summary
      cd16508
      Location:106 → 146
      RING-HC_HAKAI_like; RING finger, HC subclass, found in E3 ubiquitin-protein ligase Hakai, zinc finger protein 645 (ZNF645), and similar proteins
      pfam18408
      Location:174 → 205
      zf_Hakai; C2H2 Hakai zinc finger domain

    4. XM_012958649.3 → XP_012814103.2  E3 ubiquitin-protein ligase Hakai isoform X1

      UniProtKB/TrEMBL
      A0A6I8RYM5, A0A8J0SHW0
      Related
      ENSXETP00000090410.2, ENSXETT00000086939.2
      Conserved Domains (2) summary
      cd16508
      Location:107 → 147
      RING-HC_HAKAI_like; RING finger, HC subclass, found in E3 ubiquitin-protein ligase Hakai, zinc finger protein 645 (ZNF645), and similar proteins
      pfam18408
      Location:175 → 206
      zf_Hakai; C2H2 Hakai zinc finger domain

    5. XM_012958651.3 → XP_012814105.2  E3 ubiquitin-protein ligase Hakai isoform X3

      UniProtKB/TrEMBL
      A0A6I8RYM5, A0A8J0SHV7
      Conserved Domains (2) summary
      cd16508
      Location:104 → 144
      RING-HC_HAKAI_like; RING finger, HC subclass, found in E3 ubiquitin-protein ligase Hakai, zinc finger protein 645 (ZNF645), and similar proteins
      pfam18408
      Location:172 → 203
      zf_Hakai; C2H2 Hakai zinc finger domain
    Nucleotide Protein Strain
    Heading Accession and Version

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