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    msh6 mutS homolog 6 [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 100145639, updated on 8-Mar-2024

    Summary

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    Official Symbol
    msh6provided by Xenbase
    Official Full Name
    mutS homolog 6provided by Xenbase
    Primary source
    Xenbase:XB-GENE-986638
    See related
    Ensembl:ENSXETG00000022635
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 5
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 5 NC_030681.2 (21074694..21087144)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 5 NC_030681.1 (17099290..17111477)

    Chromosome 5 - NC_030681.2Genomic Context describing neighboring genes Neighboring gene protein spinster homolog 1-like Neighboring gene cleavage stimulation factor subunit 3-like Neighboring gene F-box protein 11 Neighboring gene forkhead box N2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP-dependent DNA damage sensor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mismatched DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA damage response IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within DNA repair IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within mismatch repair IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    DNA mismatch repair protein Msh6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030681.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      21074694..21087144
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002935375.4 → XP_002935421.3  DNA mismatch repair protein Msh6

      UniProtKB/TrEMBL
      A0A803JPE5, F7EDR7
      Related
      ENSXETP00000108376.1, ENSXETT00000113337.1
      Conserved Domains (3) summary
      cd05837
      Location:74 → 181
      MSH6_like; The PWWP domain is present in MSH6, a mismatch repair protein homologous to bacterial MutS. The PWWP domain of histone-lysine N-methyltransferase, also known as Nuclear SET domain-containing protein 3, is also included. Mutations in MSH6 have been ...
      COG0249
      Location:386 → 1304
      MutS; DNA mismatch repair ATPase MutS [Replication, recombination and repair]
      NF033845
      Location:165 → 314
      MSCRAMM_ClfB; MSCRAMM family adhesin clumping factor ClfB
    Nucleotide Protein Strain
    Heading Accession and Version

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