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    scn3a sodium channel, voltage gated, type III alpha subunit [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 100125099, updated on 15-Oct-2023

    Summary

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    Official Symbol
    scn3aprovided by Xenbase
    Official Full Name
    sodium channel, voltage gated, type III alpha subunitprovided by Xenbase
    Primary source
    Xenbase:XB-GENE-5812330
    See related
    Ensembl:ENSXETG00000008965
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Also known as
    nav1.3; na(v)1.3
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    Genomic context

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    Location:
    chromosome: 9
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 9 NC_030685.2 (70451249..70556682)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 9 NC_030685.1 (65349039..65452345)

    Chromosome 9 - NC_030685.2Genomic Context describing neighboring genes Neighboring gene sodium channel, voltage gated, type II alpha subunit Neighboring gene uncharacterized LOC116407830 Neighboring gene uncharacterized LOC116407655 Neighboring gene solute carrier family 38 member 11 Neighboring gene cordon-bleu WH2 repeat protein like 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables monoatomic cation channel activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables monoatomic ion channel activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sodium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables voltage-gated sodium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within monoatomic ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within monoatomic ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within sodium ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of monoatomic ion channel complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of voltage-gated sodium channel complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    sodium channel protein type 2 subunit alpha

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030685.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      70451249..70556682
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_031892884.1 → XP_031748744.1  sodium channel protein type 2 subunit alpha isoform X3

      UniProtKB/TrEMBL
      A0A6I8RPL8, A0A8J1IT15
      Conserved Domains (4) summary
      cd13433
      Location:1488 → 1540
      Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
      pfam00520
      Location:1221 → 1496
      Ion_trans; Ion transport protein
      pfam06512
      Location:1008 → 1216
      Na_trans_assoc; Sodium ion transport-associated
      pfam11933
      Location:511 → 719
      Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel

    2. XM_012971260.3 → XP_012826714.1  sodium channel protein type 2 subunit alpha isoform X1

      UniProtKB/TrEMBL
      A0A6I8RPL8, A0A8J0SWE1
      Conserved Domains (4) summary
      cd13433
      Location:1488 → 1540
      Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
      pfam00520
      Location:1239 → 1496
      Ion_trans; Ion transport protein
      pfam06512
      Location:1008 → 1216
      Na_trans_assoc; Sodium ion transport-associated
      pfam11933
      Location:512 → 627
      Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel

    3. XM_031892885.1 → XP_031748745.1  sodium channel protein type 2 subunit alpha isoform X4

      UniProtKB/TrEMBL
      A0A8J1IVF8, F6TZ24
      Related
      ENSXETP00000019653.4, ENSXETT00000019653.4

    4. XM_031892883.1 → XP_031748743.1  sodium channel protein type 2 subunit alpha isoform X2

      UniProtKB/TrEMBL
      A0A6I8RPL8, A0A8J1IT19
      Related
      ENSXETP00000086769.1, ENSXETT00000100805.2
      Conserved Domains (4) summary
      cd13433
      Location:1488 → 1540
      Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
      pfam00520
      Location:1221 → 1496
      Ion_trans; Ion transport protein
      pfam06512
      Location:1008 → 1216
      Na_trans_assoc; Sodium ion transport-associated
      pfam11933
      Location:511 → 719
      Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel

    5. XM_031892886.1 → XP_031748746.1  sodium channel protein type 2 subunit alpha isoform X5

      UniProtKB/TrEMBL
      A0A8J1IW78, F6TZ24
      Conserved Domains (4) summary
      cd13433
      Location:1477 → 1529
      Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
      pfam00520
      Location:1210 → 1485
      Ion_trans; Ion transport protein
      pfam06512
      Location:997 → 1205
      Na_trans_assoc; Sodium ion transport-associated
      pfam11933
      Location:511 → 708
      Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
    Nucleotide Protein Strain
    Heading Accession and Version

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