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    fga fibrinogen alpha chain [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 100038060, updated on 8-Mar-2024

    Summary

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    Official Symbol
    fgaprovided by Xenbase
    Official Full Name
    fibrinogen alpha chainprovided by Xenbase
    Primary source
    Xenbase:XB-GENE-478771
    See related
    Ensembl:ENSXETG00000026093
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Also known as
    fib2; fibrinogen
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 1 NC_030677.2 (54510727..54521750)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 1 NC_030677.1 (45271099..45281710)

    Chromosome 1 - NC_030677.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC116411984 Neighboring gene fibrinogen gamma chain Neighboring gene fibrinogen alpha chain Neighboring gene fibrinogen beta chain

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC53620

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables signaling receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within blood coagulation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within blood coagulation, fibrin clot formation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within hemostasis IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within platelet activation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within platelet aggregation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within positive regulation of blood coagulation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within protein polymerization IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of fibrinogen complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    fibrinogen alpha chain

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030677.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      54510727..54521750
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002933489.5 → XP_002933535.3  fibrinogen alpha chain

      UniProtKB/TrEMBL
      F6SP35
      Related
      ENSXETP00000048523.5, ENSXETT00000048523.5
      Conserved Domains (3) summary
      cd00087
      Location:523 → 757
      FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
      pfam08702
      Location:51 → 191
      Fib_alpha; Fibrinogen alpha/beta chain family
      pfam12160
      Location:299 → 372
      Fibrinogen_aC; Fibrinogen alpha C domain
    Nucleotide Protein Strain
    Heading Accession and Version

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