slc7a8a solute carrier family 7 member 8a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: slc7a8aprovided by ZNC
Official Full Name: solute carrier family 7 member 8aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-121120-2
See related: Ensembl:ENSDARG00000075831 AllianceGenome:ZFIN:ZDB-GENE-121120-2
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary: Predicted to enable L-amino acid transmembrane transporter activity and neutral amino acid transmembrane transporter activity. Predicted to be involved in amino acid transmembrane transport and neutral amino acid transport. Predicted to act upstream of or within amino acid transport and transmembrane transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human SLC7A8 (solute carrier family 7 member 8). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 7

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	7	NC_007118.7 (24210086..24236282, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	7	NC_007118.6 (23938929..23965125, complement)

Chromosome 7 - NC_007118.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fc32h07.y1 (e-PCR)
- UniSTS:193559

fc39h12.x1 (e-PCR)
- UniSTS:203920

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables L-amino acid transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables neutral L-amino acid transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables transmembrane transporter activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in amino acid transmembrane transport	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within amino acid transport	IEA Inferred from Electronic Annotation more info
involved_in neutral amino acid transport	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in basolateral plasma membrane	IEA Inferred from Electronic Annotation more info
located_in lateral plasma membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: solute carrier family 7 member 8a

Names: solute carrier family 7 (amino acid transporter light chain, L system), member 8a; solute carrier family 7 (cationic amino acid transporter, y+ system), member 8a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001271897.1 → NP_001258826.1 solute carrier family 7 member 8a

Status: VALIDATED

Source sequence(s)

CR318603

UniProtKB/TrEMBL

A0A8M1P532, E7EXU6

Related

ENSDARP00000012295.8, ENSDART00000010124.10

Conserved Domains (1) summary

TIGR00911
Location:1 → 497

2A0308; L-type amino acid transporter