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    Mvb12a multivesicular body subunit 12A [ Mus musculus (house mouse) ]

    Gene ID: 73711, updated on 26-Jun-2015
    Official Symbol
    Mvb12aprovided by MGI
    Official Full Name
    multivesicular body subunit 12Aprovided by MGI
    Primary source
    MGI:MGI:1920961
    See related
    Ensembl:ENSMUSG00000031813
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Fam125a; 1110012M11Rik
    Orthologs
    See Mvb12a in Epigenomics, MapViewer
    Location:
    8; 8 C1
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    105 current GRCm38.p3 (GCF_000001635.23) 8 NC_000074.6 (71542880..71548026)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (74066829..74071925)

    Chromosome 8 - NC_000074.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA C430049E01 gene Neighboring gene 14-3-3 protein sigma-like Neighboring gene bone marrow stromal cell antigen 2 Neighboring gene transmembrane protein 221 Neighboring gene nucleoredoxin-like 1

    • ESCRT-I complex, organism-specific biosystem (from KEGG)
      ESCRT-I complex, organism-specific biosystemStructural complex; Genetic information processing; Protein processing
    • ESCRT-I complex, conserved biosystem (from KEGG)
      ESCRT-I complex, conserved biosystemStructural complex; Genetic information processing; Protein processing
    • Endocytosis, organism-specific biosystem (from KEGG)
      Endocytosis, organism-specific biosystemEndocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins, and lipids from the cell surface, bringing them into the cell interior. Transmembrane proteins en...
    • Endocytosis, conserved biosystem (from KEGG)
      Endocytosis, conserved biosystemEndocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins, and lipids from the cell surface, bringing them into the cell interior. Transmembrane proteins en...

    Markers

    Homology

    Clone Names

    • MGC99951

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    SH3 domain binding IEA
    Inferred from Electronic Annotation
    more info
     
    lipid binding ISO
    Inferred from Sequence Orthology
    more info
     
    ubiquitin binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    positive regulation of viral process ISO
    Inferred from Sequence Orthology
    more info
     
    protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of epidermal growth factor receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of viral budding via host ESCRT complex ISO
    Inferred from Sequence Orthology
    more info
     
    transport IEA
    Inferred from Electronic Annotation
    more info
     
    virus maturation ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    ESCRT I complex ISO
    Inferred from Sequence Orthology
    more info
     
    aggresome ISO
    Inferred from Sequence Orthology
    more info
     
    centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    endosome IEA
    Inferred from Electronic Annotation
    more info
     
    extracellular exosome ISO
    Inferred from Sequence Orthology
    more info
     
    intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    multivesicular body subunit 12A
    Names
    multivesicular body subunit 12A
    ESCRT-I complex subunit MVB12A
    family with sequence similarity 125, member A

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_028617.2NP_082893.1  multivesicular body subunit 12A

      See identical proteins and their annotated locations for NP_082893.1

      Status: PROVISIONAL

      Source sequence(s)
      BC020119
      Consensus CDS
      CCDS22398.1
      UniProtKB/Swiss-Prot
      Q78HU3
      Related
      ENSMUSP00000034272, ENSMUST00000034272
      Conserved Domains (1) summary
      pfam10240
      Location:8259
      DUF2464; Protein of unknown function (DUF2464)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p3 C57BL/6J

    Genomic

    1. NC_000074.6 Reference GRCm38.p3 C57BL/6J

      Range
      71542880..71548026
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011242330.1XP_011240632.1  

      Conserved Domains (1) summary
      pfam10240
      Location:863
      DUF2464; Protein of unknown function (DUF2464)
    2. XM_006509763.2XP_006509826.1  

      See identical proteins and their annotated locations for XP_006509826.1

      Conserved Domains (1) summary
      pfam10240
      Location:1157
      DUF2464; Protein of unknown function (DUF2464)
    3. XM_006509762.2XP_006509825.1  

      See identical proteins and their annotated locations for XP_006509825.1

      Conserved Domains (1) summary
      pfam10240
      Location:1157
      DUF2464; Protein of unknown function (DUF2464)
    4. XM_006509764.1XP_006509827.1  

      See identical proteins and their annotated locations for XP_006509827.1

      Conserved Domains (1) summary
      pfam10240
      Location:1157
      DUF2464; Protein of unknown function (DUF2464)

    Alternate Mm_Celera

    Genomic

    1. AC_000030.1 Alternate Mm_Celera

      Range
      74053836..74058731
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)