Display Settings:

Format

Send to:

Choose Destination
    • Showing Current items.

    RPL32 ribosomal protein L32 [ Homo sapiens (human) ]

    Gene ID: 6161, updated on 26-Jun-2015
    Official Symbol
    RPL32provided by HGNC
    Official Full Name
    ribosomal protein L32provided by HGNC
    Primary source
    HGNC:HGNC:10336
    See related
    Ensembl:ENSG00000144713; HPRD:17995
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    L32; PP9932
    Summary
    Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L32E family of ribosomal proteins. It is located in the cytoplasm. Although some studies have mapped this gene to 3q13.3-q21, it is believed to map to 3p25-p24. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008]
    Orthologs
    See RPL32 in Epigenomics, MapViewer
    Location:
    3p25-p24
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    107 current GRCh38.p2 (GCF_000001405.28) 3 NC_000003.12 (12834945..12841582, complement)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (12876444..12883081, complement)

    Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene keratin 18 pseudogene 17 Neighboring gene uncharacterized LOC105376953 Neighboring gene cullin-associated and neddylation-dissociated 2 (putative) Neighboring gene small nucleolar RNA, H/ACA box 7A Neighboring gene MAP/microtubule affinity-regulating kinase 4 pseudogene Neighboring gene MAP/microtubule affinity-regulating kinase 3 pseudogene 2

    Protein interactions

    Protein Gene Interaction Pubs
    Rev rev HIV-1 Rev interacting protein, ribosomal protein L32 (RPL32), is identified by the in-vitro binding experiments involving cytosolic or nuclear extracts from HeLa cells PubMed

    Go to the HIV-1, Human Interaction Database

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    poly(A) RNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    structural constituent of ribosome NAS
    Non-traceable Author Statement
    more info
    PubMed 
    Process Evidence Code Pubs
    SRP-dependent cotranslational protein targeting to membrane TAS
    Traceable Author Statement
    more info
     
    cellular protein metabolic process TAS
    Traceable Author Statement
    more info
     
    gene expression TAS
    Traceable Author Statement
    more info
     
    nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS
    Traceable Author Statement
    more info
     
    translation NAS
    Non-traceable Author Statement
    more info
    PubMed 
    translation TAS
    Traceable Author Statement
    more info
     
    translational elongation TAS
    Traceable Author Statement
    more info
     
    translational initiation TAS
    Traceable Author Statement
    more info
     
    translational termination TAS
    Traceable Author Statement
    more info
     
    viral life cycle TAS
    Traceable Author Statement
    more info
     
    viral process TAS
    Traceable Author Statement
    more info
     
    viral transcription TAS
    Traceable Author Statement
    more info
     
    Component Evidence Code Pubs
    centrosome IDA
    Inferred from Direct Assay
    more info
     
    cytoplasm IDA
    Inferred from Direct Assay
    more info
     
    cytosol TAS
    Traceable Author Statement
    more info
     
    cytosolic large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    PubMed 
    membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    60S ribosomal protein L32
    Names
    60S ribosomal protein L32

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_000994.3NP_000985.1  60S ribosomal protein L32

      See identical proteins and their annotated locations for NP_000985.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) represents the predominant transcript. Variants 1, 2 and 3 encode the same protein.
      Source sequence(s)
      AC034198, CA436299, CF124158
      Consensus CDS
      CCDS2614.1
      UniProtKB/TrEMBL
      A0A024R2G7
      UniProtKB/Swiss-Prot
      P62910
      Conserved Domains (1) summary
      cd00513
      Location:18124
      Ribosomal_L32_L32e; Ribosomal_L32_L32e: L32 is a protein from the large subunit that contains a surface-exposed globular domain and a finger-like projection that extends into the RNA core to stabilize the tertiary structure. L32 does not appear to play a role in forming the ...
    2. NM_001007073.1NP_001007074.1  60S ribosomal protein L32

      See identical proteins and their annotated locations for NP_001007074.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) has an additional segment in the 5' UTR, compared to variant 1. Variants 1, 2 and 3 encode the same protein.
      Source sequence(s)
      AC034198, BQ068496, CA436299, CF124158
      Consensus CDS
      CCDS2614.1
      UniProtKB/TrEMBL
      A0A024R2G7
      UniProtKB/Swiss-Prot
      P62910
      Related
      ENSP00000380158, ENST00000396957
      Conserved Domains (1) summary
      cd00513
      Location:18124
      Ribosomal_L32_L32e; Ribosomal_L32_L32e: L32 is a protein from the large subunit that contains a surface-exposed globular domain and a finger-like projection that extends into the RNA core to stabilize the tertiary structure. L32 does not appear to play a role in forming the ...
    3. NM_001007074.1NP_001007075.1  60S ribosomal protein L32

      See identical proteins and their annotated locations for NP_001007075.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) lacks a 5' exon but has an alternate segment in the 5' UTR, compared to variant 1. Variants 1, 2 and 3 encode the same protein.
      Source sequence(s)
      AC034198, BC070209, BF960792, CA436299
      Consensus CDS
      CCDS2614.1
      UniProtKB/TrEMBL
      A0A024R2G7
      UniProtKB/Swiss-Prot
      P62910
      Conserved Domains (1) summary
      cd00513
      Location:18124
      Ribosomal_L32_L32e; Ribosomal_L32_L32e: L32 is a protein from the large subunit that contains a surface-exposed globular domain and a finger-like projection that extends into the RNA core to stabilize the tertiary structure. L32 does not appear to play a role in forming the ...

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p2 Primary Assembly

    Genomic

    1. NC_000003.12 Reference GRCh38.p2 Primary Assembly

      Range
      12834945..12841582
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate CHM1_1.1

    Genomic

    1. NC_018914.2 Alternate CHM1_1.1

      Range
      12826437..12833074
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)