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    Nagk N-acetylglucosamine kinase [ Mus musculus (house mouse) ]

    Gene ID: 56174, updated on 26-Jun-2015
    Official Symbol
    Nagkprovided by MGI
    Official Full Name
    N-acetylglucosamine kinaseprovided by MGI
    Primary source
    MGI:MGI:1860418
    See related
    Ensembl:ENSMUSG00000034744; Vega:OTTMUSG00000023757
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gnk
    Orthologs
    See Nagk in Epigenomics, MapViewer
    Location:
    6; 6 D1
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    105 current GRCm38.p3 (GCF_000001635.23) 6 NC_000072.6 (83795031..83802556)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (83745051..83752550)

    Chromosome 6 - NC_000072.6Genomic Context describing neighboring genes Neighboring gene testis expressed gene 261 Neighboring gene ribosomal protein L27 pseudogene Neighboring gene poly(A) binding protein interacting protein 2B Neighboring gene ribosomal protein L18 pseudogene

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (2) 

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    N-acetylglucosamine kinase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    N-acetylglucosamine kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    N-acylmannosamine kinase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    N-acetylglucosamine metabolic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    N-acetylneuraminate catabolic process TAS
    Traceable Author Statement
    more info
    PubMed 
    carbohydrate phosphorylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    carbohydrate phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    extracellular exosome ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    N-acetyl-D-glucosamine kinase
    Names
    N-acetyl-D-glucosamine kinase
    GlcNAc kinase
    NP_001157659.1
    NP_062415.1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001164187.1NP_001157659.1  N-acetyl-D-glucosamine kinase isoform 2

      See identical proteins and their annotated locations for NP_001157659.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate first exon and encodes a shorter protein (isoform 2).
      Source sequence(s)
      AC090647, AC156283
      Conserved Domains (1) summary
      cl17037
      Location:1230
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily
    2. NM_019542.2NP_062415.1  N-acetyl-D-glucosamine kinase isoform 1

      See identical proteins and their annotated locations for NP_062415.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) uses an alternate first exon and encodes a longer protein (isoform 1).
      Source sequence(s)
      AC090647, AC156283
      Consensus CDS
      CCDS20286.1
      UniProtKB/TrEMBL
      Q3U2G9
      UniProtKB/Swiss-Prot
      Q9QZ08
      Related
      ENSMUSP00000042026, OTTMUSP00000028070, ENSMUST00000037376, OTTMUST00000058043
      Conserved Domains (1) summary
      cd00012
      Location:7129
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p3 C57BL/6J

    Genomic

    1. NC_000072.6 Reference GRCm38.p3 C57BL/6J

      Range
      83795031..83802556
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006506407.2XP_006506470.1  

      See identical proteins and their annotated locations for XP_006506470.1

      UniProtKB/TrEMBL
      Q9D997
      Related
      ENSMUSP00000109482, OTTMUSP00000028071, ENSMUST00000113851, OTTMUST00000058044
      Conserved Domains (1) summary
      cd00012
      Location:29147
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily
    2. XM_006506408.1XP_006506471.1  

      Conserved Domains (1) summary
      cl17037
      Location:4251
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily
    3. XM_006506409.1XP_006506472.1  

      See identical proteins and their annotated locations for XP_006506472.1

      Conserved Domains (1) summary
      cl17037
      Location:25195
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily
    4. XM_006506410.1XP_006506473.1  

      See identical proteins and their annotated locations for XP_006506473.1

      Conserved Domains (1) summary
      cl17037
      Location:25195
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    Alternate Mm_Celera

    Genomic

    1. AC_000028.1 Alternate Mm_Celera

      Range
      85778192..85785696
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)