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    slc12a2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 [ Danio rerio (zebrafish) ]

    Gene ID: 415170, updated on 27-Jun-2015
    Official Symbol
    slc12a2provided by ZNC
    Official Full Name
    solute carrier family 12 (sodium/potassium/chloride transporter), member 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040625-53
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
    Also known as
    slc12a4; zgc:85961
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
    See slc12a2 in MapViewer
    Location:
    chromosome: 10
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    104 current GRCz10 (GCF_000002035.5) 10 NC_007121.6 (16267691..16306232) , (16347694..16385677, complement)
    103 previous assembly Zv9 (GCF_000002035.4) 10 NC_007121.5 (16254384..16292925) , (16850999..16888982, complement)

    Chromosome 10 - NC_007121.6Genomic Context describing neighboring genes Neighboring gene proline-rich coiled-coil 1 Neighboring gene cortexin 3 Neighboring gene fibrillin-2 Neighboring gene fibrillin 2a Neighboring gene long-chain fatty acid transport protein 6-like

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    cation:chloride symporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    potassium ion symporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    potassium:chloride symporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    cell volume homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    chloride ion homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    chloride transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    ear development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    inner ear morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    potassium ion homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    potassium ion import IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    swim bladder inflation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    basolateral plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    Preferred Names
    solute carrier family 12 member 2
    Names
    solute carrier family 12 member 2
    little ears
    lte
    solute carrier family 12 (potassium/chloride transporters), member 2
    solute carrier family 12 (potassium/chloride transporters), member 4
    zfnkcc1
    zmp:0000000537

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001002080.1NP_001002080.1  solute carrier family 12 member 2 isoform 1

      See identical proteins and their annotated locations for NP_001002080.1

      Status: PROVISIONAL

      Source sequence(s)
      BC071283
      UniProtKB/TrEMBL
      Q6IQW8
      Conserved Domains (2) summary
      TIGR00930
      Location:1381136
      2a30; K-Cl cotransporter
      pfam08403
      Location:123191
      AA_permease_N; Amino acid permease N-terminal
    2. NM_001163654.1NP_001157126.1  solute carrier family 12 member 2 isoform 2

      See identical proteins and their annotated locations for NP_001157126.1

      Status: PROVISIONAL

      Source sequence(s)
      GQ259737
      UniProtKB/TrEMBL
      C7EA90
      Conserved Domains (2) summary
      pfam08403
      Location:123191
      AA_permease_N; Amino acid permease N-terminal
      TIGR00930
      Location:1381120
      2a30; K-Cl cotransporter

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 104

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz10 Primary Assembly

    Genomic

    1. NC_007121.6 Reference GRCz10 Primary Assembly

      Range
      16267691..16306232
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    2. NC_007121.6 Reference GRCz10 Primary Assembly

      Range
      16347694..16385677
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)