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    Rabgap1l RAB GTPase activating protein 1-like [ Mus musculus (house mouse) ]

    Gene ID: 29809, updated on 27-Jun-2015
    Official Symbol
    Rabgap1lprovided by MGI
    Official Full Name
    RAB GTPase activating protein 1-likeprovided by MGI
    Primary source
    MGI:MGI:1352507
    See related
    Ensembl:ENSMUSG00000026721; Vega:OTTMUSG00000050683
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    HHL; Hh1; AW049894; mKIAA0471; 5830411O09Rik; 8430421H08Rik; 9630005B12Rik
    Orthologs
    See Rabgap1l in Epigenomics, MapViewer
    Location:
    1; 1 H2.1
    Exon count:
    34
    Annotation release Status Assembly Chr Location
    105 current GRCm38.p3 (GCF_000001635.23) 1 NC_000067.6 (160219174..160793476, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (162149305..162723069, complement)

    Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene mitochondrial ribosomal protein S14 Neighboring gene calcyclin binding protein Neighboring gene microRNA 1927 Neighboring gene G protein-coupled receptor 52 Neighboring gene ribosomal protein L23A pseudogene Neighboring gene RING CCCH (C3H) domains 1

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    GTPase activator activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Rab GTPase binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    megakaryocyte development NAS
    Non-traceable Author Statement
    more info
    PubMed 
    positive regulation of GTPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of protein localization ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Component Evidence Code Pubs
    Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    early endosome ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Preferred Names
    rab GTPase-activating protein 1-like
    Names
    rab GTPase-activating protein 1-like
    rab6 GTPase activating protein-like
    rabgap1l

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001038621.2NP_001033710.1  rab GTPase-activating protein 1-like isoform b

      See identical proteins and their annotated locations for NP_001033710.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (b) has a shorter and distinct N-terminus compared to isoform a.
      Source sequence(s)
      AK147634
      Consensus CDS
      CCDS15407.1
      UniProtKB/Swiss-Prot
      A6H6A9
      Related
      ENSMUSP00000028052, OTTMUSP00000069119, ENSMUST00000028052, OTTMUST00000128485
      Conserved Domains (1) summary
      TIGR02168
      Location:113322
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    2. NM_013862.5NP_038890.3  rab GTPase-activating protein 1-like isoform a

      See identical proteins and their annotated locations for NP_038890.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
      Source sequence(s)
      AC154873, AK035796, BC145811
      Consensus CDS
      CCDS15408.1
      UniProtKB/Swiss-Prot
      A6H6A9
      Related
      ENSMUSP00000028049, OTTMUSP00000069124, ENSMUST00000028049, OTTMUST00000128494
      Conserved Domains (3) summary
      cd01211
      Location:129257
      PTB_Rab6GAP; GTPase activating protein for Rab 6 Phosphotyrosine-binding (PTB) domain
      pfam00566
      Location:541744
      RabGAP-TBC; Rab-GTPase-TBC domain
      pfam12473
      Location:290422
      DUF3694; Kinesin protein

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p3 C57BL/6J

    Genomic

    1. NC_000067.6 Reference GRCm38.p3 C57BL/6J

      Range
      160219174..160793476
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006496876.1XP_006496939.1  

      Conserved Domains (3) summary
      cd01211
      Location:101229
      PTB_Rab6GAP; GTPase activating protein for Rab 6 Phosphotyrosine-binding (PTB) domain
      pfam00566
      Location:513716
      RabGAP-TBC; Rab-GTPase-TBC domain
      pfam12473
      Location:262394
      DUF3694; Kinesin protein
    2. XM_006496877.2XP_006496940.1  

      Conserved Domains (3) summary
      cd01211
      Location:92220
      PTB_Rab6GAP; GTPase activating protein for Rab 6 Phosphotyrosine-binding (PTB) domain
      pfam00566
      Location:504707
      RabGAP-TBC; Rab-GTPase-TBC domain
      pfam12473
      Location:253385
      DUF3694; Kinesin protein
    3. XM_006496875.1XP_006496938.1  

      Conserved Domains (3) summary
      cd01211
      Location:129257
      PTB_Rab6GAP; GTPase activating protein for Rab 6 Phosphotyrosine-binding (PTB) domain
      pfam00566
      Location:541744
      RabGAP-TBC; Rab-GTPase-TBC domain
      pfam12473
      Location:290422
      DUF3694; Kinesin protein
    4. XM_006496878.2XP_006496941.1  

      Conserved Domains (3) summary
      cd01211
      Location:71199
      PTB_Rab6GAP; GTPase activating protein for Rab 6 Phosphotyrosine-binding (PTB) domain
      pfam00566
      Location:483686
      RabGAP-TBC; Rab-GTPase-TBC domain
      pfam12473
      Location:232364
      DUF3694; Kinesin protein
    5. XM_006496881.2XP_006496944.1  

      Conserved Domains (1) summary
      COG1196
      Location:68276
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    6. XM_006496882.2XP_006496945.1  

      Conserved Domains (1) summary
      COG1196
      Location:62276
      Smc; Chromosome segregation ATPases [Cell division and chromosome partitioning]
    7. XM_006496883.2XP_006496946.1  

      See identical proteins and their annotated locations for XP_006496946.1

      UniProtKB/Swiss-Prot
      A6H6A9
    8. XM_006496879.2XP_006496942.1  

      Conserved Domains (3) summary
      cd01211
      Location:129257
      PTB_Rab6GAP; GTPase activating protein for Rab 6 Phosphotyrosine-binding (PTB) domain
      pfam12473
      Location:290422
      DUF3694; Kinesin protein
      cl02495
      Location:535569
      RabGAP-TBC; Rab-GTPase-TBC domain
    9. XM_006496880.1XP_006496943.1  

      Conserved Domains (2) summary
      cd01211
      Location:129257
      PTB_Rab6GAP; GTPase activating protein for Rab 6 Phosphotyrosine-binding (PTB) domain
      pfam12473
      Location:290422
      DUF3694; Kinesin protein

    Alternate Mm_Celera

    Genomic

    1. AC_000023.1 Alternate Mm_Celera

      Range
      162630945..163158157
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)