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    Ikzf4 IKAROS family zinc finger 4 [ Mus musculus (house mouse) ]

    Gene ID: 22781, updated on 26-Jun-2015
    Official Symbol
    Ikzf4provided by MGI
    Official Full Name
    IKAROS family zinc finger 4provided by MGI
    Primary source
    MGI:MGI:1343139
    See related
    Ensembl:ENSMUSG00000002578; Vega:OTTMUSG00000025110
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Eos; Zfpn1a4; Znfn1a4; A630026H08Rik
    Orthologs
    See Ikzf4 in Epigenomics, MapViewer
    Location:
    10; 10 D3
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    105 current GRCm38.p3 (GCF_000001635.23) 10 NC_000076.6 (128630839..128669358, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (128069471..128083049, complement)

    Chromosome 10 - NC_000076.6Genomic Context describing neighboring genes Neighboring gene predicted gene 9182 Neighboring gene ribosomal protein S26 Neighboring gene predicted gene, 26876 Neighboring gene predicted gene, 40807 Neighboring gene sulfite oxidase Neighboring gene ribosomal protein L12 pseudogene

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    bHLH transcription factor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein heterodimerization activity IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein homodimerization activity IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    negative regulation of transcription, DNA-templated IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    positive regulation of transcription from RNA polymerase II promoter IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    Preferred Names
    zinc finger protein Eos
    Names
    zinc finger protein Eos
    ikaros family zinc finger protein 4
    zinc finger protein, subfamily 1A, 4 (Eos)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_011772.2NP_035902.2  zinc finger protein Eos

      See identical proteins and their annotated locations for NP_035902.2

      Status: VALIDATED

      Source sequence(s)
      AC117232, AK089522
      Consensus CDS
      CCDS24284.2
      UniProtKB/Swiss-Prot
      Q8C208
      Conserved Domains (1) summary
      pfam13465
      Location:174198
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p3 C57BL/6J

    Genomic

    1. NC_000076.6 Reference GRCm38.p3 C57BL/6J

      Range
      128630839..128669358
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006513613.2XP_006513676.1  

      See identical proteins and their annotated locations for XP_006513676.1

      Conserved Domains (2) summary
      pfam13465
      Location:127151
      zf-H2C2_2; Zinc-finger double domain
      sd00017
      Location:113190
      ZF_C2H2; Zinc finger, C2H2 type
    2. XM_011243441.1XP_011241743.1  

      See identical proteins and their annotated locations for XP_011241743.1

      Conserved Domains (2) summary
      pfam13465
      Location:127151
      zf-H2C2_2; Zinc-finger double domain
      sd00017
      Location:113190
      ZF_C2H2; Zinc finger, C2H2 type
    3. XM_006513614.1XP_006513677.1  

      See identical proteins and their annotated locations for XP_006513677.1

      UniProtKB/Swiss-Prot
      Q8C208
      Conserved Domains (1) summary
      pfam13465
      Location:119143
      zf-H2C2_2; Zinc-finger double domain
    4. XM_011243442.1XP_011241744.1  

      See identical proteins and their annotated locations for XP_011241744.1

      Related
      ENSMUSP00000114404, OTTMUSP00000030370, ENSMUST00000133342, OTTMUST00000061771
      Conserved Domains (2) summary
      pfam13465
      Location:121145
      zf-H2C2_2; Zinc-finger double domain
      sd00017
      Location:108128
      ZF_C2H2; Zn binding site [ion binding]
    5. XM_006513615.1XP_006513678.1  

      See identical proteins and their annotated locations for XP_006513678.1

      UniProtKB/Swiss-Prot
      Q8C208
      Conserved Domains (1) summary
      pfam13465
      Location:119143
      zf-H2C2_2; Zinc-finger double domain
    6. XM_011243440.1XP_011241742.1  

      See identical proteins and their annotated locations for XP_011241742.1

      Conserved Domains (2) summary
      pfam13465
      Location:129153
      zf-H2C2_2; Zinc-finger double domain
      sd00017
      Location:115192
      ZF_C2H2; Zinc finger, C2H2 type
    7. XM_006513612.1XP_006513675.1  

      See identical proteins and their annotated locations for XP_006513675.1

      Conserved Domains (2) summary
      pfam13465
      Location:129153
      zf-H2C2_2; Zinc-finger double domain
      sd00017
      Location:115192
      ZF_C2H2; Zinc finger, C2H2 type
    8. XM_006513616.1XP_006513679.1  

      Conserved Domains (2) summary
      COG5048
      Location:83140
      COG5048; FOG: Zn-finger [General function prediction only]
      pfam13465
      Location:99124
      zf-H2C2_2; Zinc-finger double domain

    Alternate Mm_Celera

    Genomic

    1. AC_000032.1 Alternate Mm_Celera

      Range
      131024505..131038081
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)