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    Tgm3 transglutaminase 3, E polypeptide [ Mus musculus (house mouse) ]

    Gene ID: 21818, updated on 26-Jun-2015
    Official Symbol
    Tgm3provided by MGI
    Official Full Name
    transglutaminase 3, E polypeptideprovided by MGI
    Primary source
    MGI:MGI:98732
    See related
    Ensembl:ENSMUSG00000027401; Vega:OTTMUSG00000015499
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    TGE; TG E; TG(E); TGase E; TGase-3; AI893889
    Orthologs
    See Tgm3 in Epigenomics, MapViewer
    Location:
    2; 2 F1
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    105 current GRCm38.p3 (GCF_000001635.23) 2 NC_000068.7 (129987794..130050399)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (129838110..129876135)

    Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4932416H05 gene Neighboring gene serine/threonine kinase 35 Neighboring gene predicted gene, 39933 Neighboring gene microRNA 6339 Neighboring gene expressed sequence AU015228 Neighboring gene transglutaminase 6

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (2)  1 citation
    • Chemically induced (ENU) (1) 

    Markers

    Homology

    Clone Names

    • MGC150256, MGC150257

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    calcium ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    catalytic activity ISO
    Inferred from Sequence Orthology
    more info
     
    catalytic activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein-glutamine gamma-glutamyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    protein-glutamine gamma-glutamyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    transferase activity, transferring acyl groups IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    cell envelope organization ISO
    Inferred from Sequence Orthology
    more info
     
    epidermis development TAS
    Traceable Author Statement
    more info
    PubMed 
    hair cell differentiation TAS
    Traceable Author Statement
    more info
    PubMed 
    keratinization IEA
    Inferred from Electronic Annotation
    more info
     
    peptide cross-linking ISO
    Inferred from Sequence Orthology
    more info
     
    peptide cross-linking TAS
    Traceable Author Statement
    more info
    PubMed 
    protein tetramerization ISO
    Inferred from Sequence Orthology
    more info
     
    skin development TAS
    Traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    cornified envelope TAS
    Traceable Author Statement
    more info
    PubMed 
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    extracellular exosome ISO
    Inferred from Sequence Orthology
    more info
     
    extrinsic component of cytoplasmic side of plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    protein-glutamine gamma-glutamyltransferase E
    Names
    protein-glutamine gamma-glutamyltransferase E
    E polypeptide
    protein-glutamine-gamma-glutamyltransferase
    transglutaminase E
    transglutaminase-3
    NP_033400.2

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009374.3NP_033400.2  protein-glutamine gamma-glutamyltransferase E precursor

      See identical proteins and their annotated locations for NP_033400.2

      Status: VALIDATED

      Source sequence(s)
      AL808127
      Consensus CDS
      CCDS38240.1
      UniProtKB/Swiss-Prot
      Q08189
      Related
      ENSMUSP00000105928, OTTMUSP00000016514, ENSMUST00000110299, OTTMUST00000036811
      Conserved Domains (3) summary
      smart00460
      Location:265357
      TGc; Transglutaminase/protease-like homologues
      pfam00868
      Location:4120
      Transglut_N; Transglutaminase family
      pfam00927
      Location:595693
      Transglut_C; Transglutaminase family, C-terminal ig like domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p3 C57BL/6J

    Genomic

    1. NC_000068.7 Reference GRCm38.p3 C57BL/6J

      Range
      129987794..130050399
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011239437.1XP_011237739.1  

      Conserved Domains (3) summary
      smart00460
      Location:271363
      TGc; Transglutaminase/protease-like homologues
      pfam00868
      Location:10126
      Transglut_N; Transglutaminase family
      pfam00927
      Location:601699
      Transglut_C; Transglutaminase family, C-terminal ig like domain
    2. XM_006499151.2XP_006499214.1  

      Conserved Domains (3) summary
      smart00460
      Location:276368
      TGc; Transglutaminase/protease-like homologues
      pfam00868
      Location:15131
      Transglut_N; Transglutaminase family
      pfam00927
      Location:606704
      Transglut_C; Transglutaminase family, C-terminal ig like domain

    Alternate Mm_Celera

    Genomic

    1. AC_000024.1 Alternate Mm_Celera

      Range
      131240745..131278693
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)