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    tbc-2 TBC-2 [ Caenorhabditis elegans ]

    Gene ID: 173986, updated on 23-Jun-2015
    Gene symbol
    tbc-2
    Gene description
    TBC-2
    Locus tag
    CELE_ZK1248.10
    Gene type
    protein coding
    RNA name
    TBC-2
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    See tbc-2 in MapViewer
    Location:
    chromosome: II
    Exon count:
    11
    Sequence:
    Chromosome: II; NC_003280.10 (5824086..5827426, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene ZK1248.4 Neighboring gene EHS-1 Neighboring gene ZK1248.11 Neighboring gene ZK1248.13 Neighboring gene COL-74

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    embryo development ending in birth or egg hatching IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    reproduction IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    late endosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Names
    TBC-2
    NP_495156.1
    • Partially confirmed by transcript evidence;
      C. elegans TBC-2 protein; contains similarity to Pfam domains PF00169 (PH domain) , PF00566 (Rab-GTPase-TBC domain) contains similarity to Interpro domains IPR000195 (Rab-GTPase-TBC domain), IPR001849 (Pleckstrin homology domain), IPR011993 (Pleckstrin homology-like domain)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      5824086..5827426
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_062755.6NP_495156.1  TBC-2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495156.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q23419
      Conserved Domains (2) summary
      smart00164
      Location:627849
      TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
      cd01265
      Location:20119
      PH_TBC1D2A; TBC1 domain family member 2A pleckstrin homology (PH) domain