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    MBLAC2 metallo-beta-lactamase domain containing 2 [ Homo sapiens (human) ]

    Gene ID: 153364, updated on 27-Jun-2015
    Official Symbol
    MBLAC2provided by HGNC
    Official Full Name
    metallo-beta-lactamase domain containing 2provided by HGNC
    Primary source
    HGNC:HGNC:33711
    See related
    Ensembl:ENSG00000176055; HPRD:14099; Vega:OTTHUMG00000131327
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Orthologs
    See MBLAC2 in Epigenomics, MapViewer
    Location:
    5q14.3
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    107 current GRCh38.p2 (GCF_000001405.28) 5 NC_000005.10 (90458203..90474768, complement)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (89754020..89770585, complement)

    Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC731157 Neighboring gene centrin, EF-hand protein, 3 Neighboring gene polymerase (RNA) III (DNA directed) polypeptide G (32kD) Neighboring gene LysM, putative peptidoglycan-binding, domain containing 3 Neighboring gene adhesion G protein-coupled receptor V1 Neighboring gene uncharacterized LOC105379077

    Markers

    Homology

    Clone Names

    • MGC46734, DKFZp686P15118

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    biological_process ND
    No biological Data available
    more info
     
    metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    extracellular exosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    metallo-beta-lactamase domain-containing protein 2
    Names
    metallo-beta-lactamase domain-containing protein 2

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_203406.1NP_981951.1  metallo-beta-lactamase domain-containing protein 2

      See identical proteins and their annotated locations for NP_981951.1

      Status: VALIDATED

      Source sequence(s)
      AI288430, AK128603, BC038230, BI918374
      Consensus CDS
      CCDS4067.1
      UniProtKB/TrEMBL
      B3KY36
      UniProtKB/Swiss-Prot
      Q68D91
      Related
      ENSP00000314776, OTTHUMP00000162004, ENST00000316610, OTTHUMT00000254098
      Conserved Domains (2) summary
      smart00849
      Location:31231
      Lactamase_B; Metallo-beta-lactamase superfamily
      COG0491
      Location:14244
      GloB; Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II [General function prediction only]

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p2 Primary Assembly

    Genomic

    1. NC_000005.10 Reference GRCh38.p2 Primary Assembly

      Range
      90458203..90474768
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate CHM1_1.1

    Genomic

    1. NC_018916.2 Alternate CHM1_1.1

      Range
      89186695..89203263
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)