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    Adcyap1r1 adenylate cyclase activating polypeptide 1 receptor 1 [ Mus musculus (house mouse) ]

    Gene ID: 11517, updated on 26-Jun-2015
    Official Symbol
    Adcyap1r1provided by MGI
    Official Full Name
    adenylate cyclase activating polypeptide 1 receptor 1provided by MGI
    Primary source
    MGI:MGI:108449
    See related
    Ensembl:ENSMUSG00000029778; Vega:OTTMUSG00000035961
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    PAC1; PAC1R; AI846590; PACAP1-R; 2900024I10Rik
    Orthologs
    See Adcyap1r1 in Epigenomics, MapViewer
    Location:
    6; 6 B3
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    105 current GRCm38.p3 (GCF_000001635.23) 6 NC_000072.6 (55451501..55501455)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (55401974..55451449)

    Chromosome 6 - NC_000072.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 6430584L05 gene Neighboring gene growth hormone releasing hormone receptor Neighboring gene predicted gene, 34441 Neighboring gene phosphoglycerate mutase 1 pseudogene Neighboring gene neurogenic differentiation 6

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ADP-ribosylation factor binding ISO
    Inferred from Sequence Orthology
    more info
     
    G-protein coupled receptor activity TAS
    Traceable Author Statement
    more info
    PubMed 
    adenylate cyclase binding ISO
    Inferred from Sequence Orthology
    more info
     
    neuropeptide binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    signal transducer activity IEA
    Inferred from Electronic Annotation
    more info
     
    transmembrane signaling receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    vasoactive intestinal polypeptide receptor activity TAS
    Traceable Author Statement
    more info
    PubMed 
    Process Evidence Code Pubs
    G-protein coupled receptor signaling pathway TAS
    Traceable Author Statement
    more info
    PubMed 
    activation of phospholipase C activity ISO
    Inferred from Sequence Orthology
    more info
     
    cAMP-mediated signaling ISO
    Inferred from Sequence Orthology
    more info
     
    cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    cell surface receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    multicellular organismal development IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of cell death ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of cAMP biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of calcium ion transport into cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of inositol phosphate biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    spermatogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    bicellular tight junction ISO
    Inferred from Sequence Orthology
    more info
     
    caveola ISO
    Inferred from Sequence Orthology
    more info
     
    cell surface ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    endosome ISO
    Inferred from Sequence Orthology
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    neuron projection ISO
    Inferred from Sequence Orthology
    more info
     
    plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    receptor complex ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    rough endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    pituitary adenylate cyclase-activating polypeptide type I receptor
    Names
    pituitary adenylate cyclase-activating polypeptide type I receptor
    PACAP type I receptor

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025372.2NP_001020543.1  pituitary adenylate cyclase-activating polypeptide type I receptor isoform 2 precursor

      See identical proteins and their annotated locations for NP_001020543.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 3' coding region, compared to variant 1. It encodes isoform 2, which lacks an internal segment and is shorter, compared to isoform 1.
      Source sequence(s)
      AI843743, AK083108, BC067039, BY286680, CA316040
      Consensus CDS
      CCDS20166.1
      UniProtKB/TrEMBL
      Q6NXJ9
      Related
      ENSMUSP00000066902, OTTMUSP00000050940, ENSMUST00000070756, OTTMUST00000092255
      Conserved Domains (2) summary
      pfam00002
      Location:150396
      7tm_2; 7 transmembrane receptor (Secretin family)
      pfam02793
      Location:52137
      HRM; Hormone receptor domain
    2. NM_007407.4NP_031433.3  pituitary adenylate cyclase-activating polypeptide type I receptor isoform 1 precursor

      See identical proteins and their annotated locations for NP_031433.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AI843743, AK083108, BC067039, BY286680, CA320747
      Consensus CDS
      CCDS20167.1
      UniProtKB/Swiss-Prot
      P70205
      UniProtKB/TrEMBL
      Q6NXJ9
      Conserved Domains (2) summary
      pfam00002
      Location:150424
      7tm_2; 7 transmembrane receptor (Secretin family)
      pfam02793
      Location:52137
      HRM; Hormone receptor domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p3 C57BL/6J

    Genomic

    1. NC_000072.6 Reference GRCm38.p3 C57BL/6J

      Range
      55451501..55501455
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006505388.2XP_006505451.1  

      See identical proteins and their annotated locations for XP_006505451.1

      Conserved Domains (2) summary
      pfam00002
      Location:150451
      7tm_2; 7 transmembrane receptor (Secretin family)
      pfam02793
      Location:52137
      HRM; Hormone receptor domain
    2. XM_011241150.1XP_011239452.1  

      See identical proteins and their annotated locations for XP_011239452.1

      Conserved Domains (2) summary
      pfam00002
      Location:150451
      7tm_2; 7 transmembrane receptor (Secretin family)
      pfam02793
      Location:52137
      HRM; Hormone receptor domain
    3. XM_011241151.1XP_011239453.1  

      Conserved Domains (2) summary
      pfam00002
      Location:129430
      7tm_2; 7 transmembrane receptor (Secretin family)
      pfam02793
      Location:52116
      HRM; Hormone receptor domain
    4. XM_011241152.1XP_011239454.1  

      Conserved Domains (2) summary
      pfam00002
      Location:150423
      7tm_2; 7 transmembrane receptor (Secretin family)
      pfam02793
      Location:52137
      HRM; Hormone receptor domain
    5. XM_011241153.1XP_011239455.1  

      Conserved Domains (2) summary
      pfam00002
      Location:129375
      7tm_2; 7 transmembrane receptor (Secretin family)
      pfam02793
      Location:52116
      HRM; Hormone receptor domain

    Alternate Mm_Celera

    Genomic

    1. AC_000028.1 Alternate Mm_Celera

      Range
      55983710..56033208
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)