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    IGSF6 immunoglobulin superfamily, member 6 [ Homo sapiens (human) ]

    Gene ID: 10261, updated on 26-Jun-2015
    Official Symbol
    IGSF6provided by HGNC
    Official Full Name
    immunoglobulin superfamily, member 6provided by HGNC
    Primary source
    HGNC:HGNC:5953
    See related
    HPRD:06938; MIM:606222
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    DORA
    Orthologs
    See IGSF6 in Epigenomics, MapViewer
    Location:
    16p12.2
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    107 current GRCh38.p2 (GCF_000001405.28) 16 NC_000016.10 (21641284..21652666, complement)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (21652605..21663987, complement)

    Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene carbonic anhydrase VA, mitochondrial pseudogene Neighboring gene uncharacterized LOC101927814 Neighboring gene methyltransferase like 9 Neighboring gene otoancorin Neighboring gene uncharacterized LOC105371126

    Protein interactions

    Protein Gene Interaction Pubs
    Tat tat HIV-1 Tat downregulates the expression of immunoglobulin superfamily, member 6 (IGSF6) in human primary T cells PubMed

    Go to the HIV-1, Human Interaction Database

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    transmembrane signaling receptor activity TAS
    Traceable Author Statement
    more info
    PubMed 
    Process Evidence Code Pubs
    cell surface receptor signaling pathway TAS
    Traceable Author Statement
    more info
    PubMed 
    immune response TAS
    Traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    integral component of plasma membrane TAS
    Traceable Author Statement
    more info
    PubMed 
    Preferred Names
    immunoglobulin superfamily member 6
    Names
    immunoglobulin superfamily member 6
    down-regulated by activation (immunoglobulin superfamily)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_005849.3NP_005840.2  immunoglobulin superfamily member 6 precursor

      See identical proteins and their annotated locations for NP_005840.2

      Status: VALIDATED

      Source sequence(s)
      AJ223183, AV717532, BC017844, CD369238
      Consensus CDS
      CCDS10599.1
      UniProtKB/Swiss-Prot
      O95976
      Conserved Domains (2) summary
      smart00410
      Location:45141
      IG_like; Immunoglobulin like
      cl11960
      Location:43141
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p2 Primary Assembly

    Genomic

    1. NC_000016.10 Reference GRCh38.p2 Primary Assembly

      Range
      21641284..21652666
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate CHM1_1.1

    Genomic

    1. NC_018927.2 Alternate CHM1_1.1

      Range
      22655503..22666885
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)