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    Plxdc2 plexin domain containing 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361282, updated on 3-Apr-2024

    Summary

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    Symbol
    Plxdc2provided by RGD
    Full Name
    plexin domain containing 2provided by RGD
    Primary source
    RGD:1305962
    See related
    Ensembl:ENSRNOG00000000142 AllianceGenome:RGD:1305962
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be integral component of membrane. Orthologous to human PLXDC2 (plexin domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Adrenal (RPKM 540.0), Lung (RPKM 518.9) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    17q12.3
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (84077793..84502831)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (79169238..79594279)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (83221795..83619291)

    Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA17 Neighboring gene MAM and LDL receptor class A domain containing 1 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC134482612 Neighboring gene uncharacterized LOC134482613 Neighboring gene uncharacterized LOC134482614 Neighboring gene uncharacterized LOC134482615

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Prunotto M, et al. J Proteomics, 2013 Apr 26. PMID 23376485
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    plexin domain-containing protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108422.2 → NP_001101892.1  plexin domain-containing protein 2 precursor

      See identical proteins and their annotated locations for NP_001101892.1

      Status: PROVISIONAL

      Source sequence(s)
      BC168868
      UniProtKB/TrEMBL
      B5DEZ8, F7EUH5
      Related
      ENSRNOP00000000155.5, ENSRNOT00000000155.5
      Conserved Domains (2) summary
      pfam01437
      Location:327 → 372
      PSI; Plexin repeat
      cl02648
      Location:191 → 282
      NIDO; Nidogen-like

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086035.1 Reference GRCr8

      Range
      84077793..84502831
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039095938.2 → XP_038951866.1  plexin domain-containing protein 2 isoform X3

      UniProtKB/TrEMBL
      B5DEZ8, F7EUH5
      Conserved Domains (2) summary
      pfam01437
      Location:327 → 372
      PSI; Plexin repeat
      cl02648
      Location:191 → 282
      NIDO; Nidogen-like

    2. XM_039095937.2 → XP_038951865.1  plexin domain-containing protein 2 isoform X3

      UniProtKB/TrEMBL
      B5DEZ8, F7EUH5
      Conserved Domains (2) summary
      pfam01437
      Location:327 → 372
      PSI; Plexin repeat
      cl02648
      Location:191 → 282
      NIDO; Nidogen-like

    3. XM_063276640.1 → XP_063132710.1  plexin domain-containing protein 2 isoform X3

      UniProtKB/TrEMBL
      B5DEZ8

    4. XM_039095939.2 → XP_038951867.1  plexin domain-containing protein 2 isoform X3

      UniProtKB/TrEMBL
      B5DEZ8, F7EUH5
      Conserved Domains (2) summary
      pfam01437
      Location:327 → 372
      PSI; Plexin repeat
      cl02648
      Location:191 → 282
      NIDO; Nidogen-like

    5. XM_063276638.1 → XP_063132708.1  plexin domain-containing protein 2 isoform X3

      UniProtKB/TrEMBL
      B5DEZ8

    6. XM_039095940.2 → XP_038951868.1  plexin domain-containing protein 2 isoform X3

      UniProtKB/TrEMBL
      B5DEZ8, F7EUH5
      Conserved Domains (2) summary
      pfam01437
      Location:327 → 372
      PSI; Plexin repeat
      cl02648
      Location:191 → 282
      NIDO; Nidogen-like

    7. XM_063276639.1 → XP_063132709.1  plexin domain-containing protein 2 isoform X3

      UniProtKB/TrEMBL
      B5DEZ8

    8. XM_017600633.3 → XP_017456122.1  plexin domain-containing protein 2 isoform X4

      UniProtKB/TrEMBL
      F7EUH5

    9. XM_039095936.2 → XP_038951864.1  plexin domain-containing protein 2 isoform X2

      UniProtKB/TrEMBL
      F7EUH5
      Conserved Domains (2) summary
      pfam01437
      Location:339 → 384
      PSI; Plexin repeat
      cl02648
      Location:203 → 294
      NIDO; Nidogen-like

    10. XM_039095935.2 → XP_038951863.1  plexin domain-containing protein 2 isoform X1

      UniProtKB/TrEMBL
      F7EUH5
      Conserved Domains (2) summary
      pfam01437
      Location:339 → 384
      PSI; Plexin repeat
      cl02648
      Location:203 → 294
      NIDO; Nidogen-like

    11. XM_063276641.1 → XP_063132711.1  plexin domain-containing protein 2 isoform X5

    Nucleotide Protein Strain
    Heading Accession and Version

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