Format

Send to:

Choose Destination

Links from PubMed

    • Showing Current items.

    Sstr4 somatostatin receptor 4 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 25555, updated on 2-Jun-2016
    Official Symbol
    Sstr4provided by RGD
    Official Full Name
    somatostatin receptor 4provided by RGD
    Primary source
    RGD:3764
    See related
    Ensembl:ENSRNOG00000004641
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Smstr4
    Summary
    transmembrane receptor for somatostatin; coupled to a G-protein which inhibits adenylyl cyclase; may also activate the mitogen-activated protein (MAP) kinase cascade [RGD, Feb 2006]
    Orthologs
    Location:
    3q41
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    105 current Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (142739781..142741644)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 3 NC_005102.3 (149151003..149152866)

    Chromosome 3 - NC_005102.4Genomic Context describing neighboring genes Neighboring gene forkhead box A2 Neighboring gene uncharacterized LOC102549662 Neighboring gene thrombomodulin Neighboring gene CD93 molecule

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    neuropeptide binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    somatostatin receptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    arachidonic acid metabolic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cell migration IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cell migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cellular response to glucocorticoid stimulus IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    chemical synaptic transmission IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    forebrain development IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    negative regulation of cAMP metabolic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    negative regulation of cell proliferation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    positive regulation of MAPK cascade IDA
    Inferred from Direct Assay
    more info
    PubMed 
    somatostatin signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    integral component of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    neuron projection IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    somatostatin receptor type 4
    Names
    SS-4-R
    SS4-R
    SS4R
    Somatostatin receptor subtype 4 Rattus norvegicus Sprague-Dawley major hippocampal somatostatin receptor (SSTR4) mRNA

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_013036.2NP_037168.1  somatostatin receptor type 4

      See identical proteins and their annotated locations for NP_037168.1

      Status: PROVISIONAL

      Source sequence(s)
      U04738
      UniProtKB/Swiss-Prot
      P30937
      Related
      ENSRNOP00000066231, ENSRNOT00000006181
      Conserved Domains (2) summary
      pfam00001
      Location:66307
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:54322
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 105 details...

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005102.4 Reference Rnor_6.0 Primary Assembly

      Range
      142739781..142741644
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Rn_Celera

    Genomic

    1. AC_000071.1 Alternate Rn_Celera

      Range
      134698650..134700513
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)