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Hexb hexosaminidase B [ Mus musculus (house mouse) ]

Gene ID: 15212, updated on 19-Sep-2014
Official Symbol
Hexbprovided by MGI
Official Full Name
hexosaminidase Bprovided by MGI
Primary source
MGI:MGI:96074
See related
Ensembl:ENSMUSG00000021665
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
See Hexb in Epigenomics, MapViewer
Location:
13 D1; 13 50.66 cM
Exon count:
14
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 13 NC_000079.6 (97176331..97198357, complement)

Chromosome 13 - NC_000079.6Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 169, member A Neighboring gene proteolipid protein 2 pseudogene Neighboring gene NSA2 ribosome biogenesis homolog (S. cerevisiae) Neighboring gene G elongation factor, mitochondrial 2 Neighboring gene ectodermal-neural cortex 1 Neighboring gene uncharacterized LOC102636278

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
beta-N-acetylglucosaminidase activity ISO
Inferred from Sequence Orthology
more info
 
beta-N-acetylhexosaminidase activity IDA
Inferred from Direct Assay
more info
PubMed 
beta-N-acetylhexosaminidase activity IGI
Inferred from Genetic Interaction
more info
PubMed 
beta-N-acetylhexosaminidase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
carbohydrate binding ISO
Inferred from Sequence Orthology
more info
 
hexosaminidase activity ISO
Inferred from Sequence Orthology
more info
 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
hydrolase activity, acting on glycosyl bonds IEA
Inferred from Electronic Annotation
more info
 
hydrolase activity, hydrolyzing O-glycosyl compounds IEA
Inferred from Electronic Annotation
more info
 
protein heterodimerization activity ISO
Inferred from Sequence Orthology
more info
 
protein homodimerization activity IDA
Inferred from Direct Assay
more info
PubMed 
protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
N-acetylglucosamine metabolic process ISO
Inferred from Sequence Orthology
more info
 
astrocyte cell migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 
cellular calcium ion homeostasis IGI
Inferred from Genetic Interaction
more info
PubMed 
cellular calcium ion homeostasis IMP
Inferred from Mutant Phenotype
more info
PubMed 
cellular protein metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
ganglioside catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
glycosaminoglycan metabolic process IGI
Inferred from Genetic Interaction
more info
PubMed 
glycosphingolipid metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
lipid storage IGI
Inferred from Genetic Interaction
more info
PubMed 
lipid storage IMP
Inferred from Mutant Phenotype
more info
PubMed 
locomotory behavior IGI
Inferred from Genetic Interaction
more info
PubMed 
locomotory behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
lysosome organization IGI
Inferred from Genetic Interaction
more info
PubMed 
lysosome organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
male courtship behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
metabolic process IEA
Inferred from Electronic Annotation
more info
 
myelination IGI
Inferred from Genetic Interaction
more info
PubMed 
neuromuscular process IMP
Inferred from Mutant Phenotype
more info
PubMed 
neuromuscular process controlling balance IGI
Inferred from Genetic Interaction
more info
PubMed 
neuromuscular process controlling balance IMP
Inferred from Mutant Phenotype
more info
PubMed 
oligosaccharide catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
oogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
penetration of zona pellucida IMP
Inferred from Mutant Phenotype
more info
PubMed 
phospholipid biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of transcription from RNA polymerase II promoter IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of cell shape IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of cellular metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
sensory perception of sound IGI
Inferred from Genetic Interaction
more info
PubMed 
sexual reproduction IMP
Inferred from Mutant Phenotype
more info
PubMed 
single fertilization IMP
Inferred from Mutant Phenotype
more info
PubMed 
skeletal system development IGI
Inferred from Genetic Interaction
more info
PubMed 
Component Evidence Code Pubs
acrosomal vesicle IDA
Inferred from Direct Assay
more info
PubMed 
cell IGI
Inferred from Genetic Interaction
more info
PubMed 
extracellular vesicular exosome ISO
Inferred from Sequence Orthology
more info
 
lysosome IDA
Inferred from Direct Assay
more info
PubMed 
lysosome ISO
Inferred from Sequence Orthology
more info
 
membrane IDA
Inferred from Direct Assay
more info
PubMed 
membrane ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
beta-hexosaminidase subunit beta
Names
beta-hexosaminidase subunit beta
hexosaminidase subunit B
beta-N-acetylhexosaminidase subunit beta
N-acetyl-beta-glucosaminidase subunit beta
NP_034552.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_010422.2NP_034552.1  beta-hexosaminidase subunit beta precursor

    See proteins identical to NP_034552.1

    Status: VALIDATED

    Source sequence(s)
    AK168825, BY145642, CD775639
    Consensus CDS
    CCDS26709.1
    UniProtKB/Swiss-Prot
    P20060
    UniProtKB/TrEMBL
    Q3TXR9
    Related
    ENSMUSP00000022169, ENSMUST00000022169
    Conserved Domains (2) summary
    cd06562
    Location:179519
    GH20_HexA_HexB-like; Beta-N-acetylhexosaminidases catalyze the removal of beta-1,4-linked N-acetyl-D-hexosamine residues from the non-reducing ends of N-acetyl-beta-D-hexosaminides including N-acetylglucosides and N-acetylgalactosides. The hexA and hexB genes encode the ...
    pfam14845
    Location:35157
    Glycohydro_20b2; beta-acetyl hexosaminidase like

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000079.6 

    Range
    97176331..97198357
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000035.1 

    Range
    100809364..100830755
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)