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    Ncc69 sodium chloride cotransporter 69 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39410, updated on 11-Jul-2015
    Official Symbol
    Ncc69provided by FlyBase
    Official Full Name
    sodium chloride cotransporter 69provided by FlyBase
    Primary source
    FLYBASE:FBgn0036279
    Locus tag
    Dmel_CG4357
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster (old-lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BEST:CK01027; CG43567; CG4357; CK01027; Dmel\CG4357; NCC69; NKCC
    See Ncc69 in Epigenomics, MapViewer
    Location:
    69B3-69B3
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    Release 6.01 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (12368646..12391444, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (12361746..12384544, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Corazonin receptor Neighboring gene CG32104 gene product from transcript CG32104-RB Neighboring gene Odorant-binding protein 69a Neighboring gene SET and MYND domain protein 4

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    amino acid transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    sodium:chloride symporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    sodium:potassium:chloride symporter activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    amino acid transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    chloride transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    potassium ion transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    potassium ion transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    rubidium ion transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    CG4357 gene product from transcript CG4357-RA
    Names
    CG4357-PA
    CG4357-PC
    CG4357-PD
    CG4357-PE
    CG4357-PF
    CG4357-PG
    Ncc69-PA
    Ncc69-PC
    Ncc69-PD
    Ncc69-PE
    Ncc69-PF
    Ncc69-PG
    sodium chloride cotransporter 69

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      12368646..12391444
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140315.4NP_648572.1  sodium chloride cotransporter 69, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648572.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VTW8
      Related
      FBpp0075719, FBtr0075987
      Conserved Domains (3) summary
      pfam08403
      Location:145184
      AA_permease_N; Amino acid permease N-terminal
      TIGR00930
      Location:1551171
      2a30; K-Cl cotransporter
      cl21473
      Location:524682
      ArsB_NhaD_permease; Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices ...
    2. NM_001274828.1NP_001261757.1  sodium chloride cotransporter 69, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261757.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PCA7
      Related
      FBpp0305973, FBtr0333839
      Conserved Domains (3) summary
      pfam08403
      Location:145184
      AA_permease_N; Amino acid permease N-terminal
      TIGR00930
      Location:1551191
      2a30; K-Cl cotransporter
      cl21473
      Location:524682
      ArsB_NhaD_permease; Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices ...
    3. NM_001274829.1NP_001261758.1  sodium chloride cotransporter 69, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261758.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PI37
      Related
      FBpp0305974, FBtr0333840
      Conserved Domains (3) summary
      pfam08403
      Location:145184
      AA_permease_N; Amino acid permease N-terminal
      TIGR00930
      Location:1551207
      2a30; K-Cl cotransporter
      cl21473
      Location:524682
      ArsB_NhaD_permease; Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices ...
    4. NM_206344.2NP_996066.1  sodium chloride cotransporter 69, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_996066.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VTW8
      Related
      FBpp0305976, FBtr0333842
      Conserved Domains (3) summary
      pfam08403
      Location:145184
      AA_permease_N; Amino acid permease N-terminal
      TIGR00930
      Location:1551171
      2a30; K-Cl cotransporter
      cl21473
      Location:524682
      ArsB_NhaD_permease; Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices ...
    5. NM_001274827.1NP_001261756.1  sodium chloride cotransporter 69, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261756.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PCA7
      Related
      FBpp0305972, FBtr0333838
      Conserved Domains (3) summary
      pfam08403
      Location:145184
      AA_permease_N; Amino acid permease N-terminal
      TIGR00930
      Location:1551191
      2a30; K-Cl cotransporter
      cl21473
      Location:524682
      ArsB_NhaD_permease; Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices ...
    6. NM_001274830.1NP_001261759.1  sodium chloride cotransporter 69, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261759.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PCA7
      Related
      FBpp0305975, FBtr0333841
      Conserved Domains (3) summary
      pfam08403
      Location:145184
      AA_permease_N; Amino acid permease N-terminal
      TIGR00930
      Location:1551191
      2a30; K-Cl cotransporter
      cl21473
      Location:524682
      ArsB_NhaD_permease; Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices ...