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    MYO2 myosin 2 [ Saccharomyces cerevisiae S288c ]

    Gene ID: 854504, updated on 16-Aug-2016
    Gene symbol
    MYO2
    Gene description
    myosin 2
    Primary source
    SGD:S000005853
    Locus tag
    YOR326W
    Gene type
    protein coding
    RNA name
    myosin 2
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    CDC66
    See MYO2 in Map Viewer
    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (925721..930445)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene glutamate-5-semialdehyde dehydrogenase Neighboring gene Frt1p Neighboring gene SNAP receptor SNC2 Neighboring gene ATP-binding cassette multidrug transporter PDR10

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Homology

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    actin binding IEA
    Inferred from Electronic Annotation
    more info
     
    actin filament binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    actin filament binding IEA
    Inferred from Electronic Annotation
    more info
     
    calmodulin binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    calmodulin binding IEA
    Inferred from Electronic Annotation
    more info
     
    microfilament motor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    motor activity IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    Golgi inheritance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    budding cell apical bud growth IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    cell division IEA
    Inferred from Electronic Annotation
    more info
     
    establishment of mitotic spindle orientation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    establishment of mitotic spindle orientation IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    membrane addition at site of cytokinesis IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    membrane addition at site of cytokinesis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    membrane addition at site of cytokinesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    mitochondrion inheritance IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    mitochondrion inheritance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    mitochondrion inheritance IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    peroxisome inheritance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    peroxisome inheritance IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    transport IEA
    Inferred from Electronic Annotation
    more info
     
    unidimensional cell growth IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    vacuole inheritance IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    vacuole inheritance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    vacuole inheritance IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    vesicle docking involved in exocytosis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    vesicle transport along actin filament IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    vesicle transport along actin filament IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    vesicle-mediated transport IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    vesicle-mediated transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    Myo2p-Vac17p-Vac8p transport complex IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    actin filament bundle IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cellular bud neck IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cellular bud neck IEA
    Inferred from Electronic Annotation
    more info
     
    cellular bud tip IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cellular bud tip IEA
    Inferred from Electronic Annotation
    more info
     
    filamentous actin IDA
    Inferred from Direct Assay
    more info
    PubMed 
    colocalizes_with fungal-type vacuole membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    incipient cellular bud site IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mating projection tip IDA
    Inferred from Direct Assay
    more info
    PubMed 
    myosin complex IEA
    Inferred from Electronic Annotation
    more info
     
    transport vesicle IDA
    Inferred from Direct Assay
    more info
    PubMed 
    vesicle IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Names
    myosin 2
    NP_014971.1
    • Type V myosin motor involved in actin-based transport of cargos; required for the polarized delivery of secretory vesicles, the vacuole, late Golgi elements, peroxisomes, and the mitotic spindle; MYO2 has a paralog, MYO4, that arose from the whole genome duplication

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      925721..930445
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183746.1NP_014971.1  myosin 2 [Saccharomyces cerevisiae S288c]

      See identical proteins and their annotated locations for NP_014971.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P19524
      Conserved Domains (4) summary
      COG5022
      Location:21567
      COG5022; Myosin heavy chain [General function prediction only]
      cd15480
      Location:11541564
      fMyo2p_CBD; cargo binding domain of fungal myosin 2
      cd01380
      Location:84769
      MYSc_Myo5; class V myosin, motor domain
      pfam13863
      Location:9771081
      DUF4200; Domain of unknown function (DUF4200)