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Pax7 paired box 7 [ Mus musculus (house mouse) ]

Gene ID: 18509, updated on 17-May-2015
Official Symbol
Pax7provided by MGI
Official Full Name
paired box 7provided by MGI
Primary source
MGI:MGI:97491
See related
Ensembl:ENSMUSG00000028736; Vega:OTTMUSG00000010060
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Pax-7
Orthologs
See Pax7 in MapViewer
Location:
4 E1; 4 70.83 cM
Exon count:
9
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 4 NC_000070.6 (139737059..139833026, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (139293996..139388883, complement)

Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene taste receptor, type 1, member 2 Neighboring gene predicted gene, 42334 Neighboring gene uncharacterized LOC102636380 Neighboring gene RIKEN cDNA 4933427I22 gene Neighboring gene kelch domain containing 7A Neighboring gene microRNA 2139

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
sequence-specific DNA binding transcription factor activity TAS
Traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
cartilage development IMP
Inferred from Mutant Phenotype
more info
PubMed 
chromatin remodeling IMP
Inferred from Mutant Phenotype
more info
PubMed 
dorsal/ventral neural tube patterning IDA
Inferred from Direct Assay
more info
PubMed 
embryonic skeletal system development IMP
Inferred from Mutant Phenotype
more info
PubMed 
multicellular organismal development IEA
Inferred from Electronic Annotation
more info
 
muscle organ development IEA
Inferred from Electronic Annotation
more info
 
muscle tissue morphogenesis IGI
Inferred from Genetic Interaction
more info
PubMed 
neuron fate commitment IGI
Inferred from Genetic Interaction
more info
PubMed 
organ morphogenesis TAS
Traceable Author Statement
more info
PubMed 
positive regulation of histone methylation IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of histone methylation IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of myoblast proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of transcription from RNA polymerase II promoter IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of cell fate commitment IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of gene expression IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of protein binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of transcription from RNA polymerase II promoter IDA
Inferred from Direct Assay
more info
PubMed 
regulation of transcription, DNA-templated TAS
Traceable Author Statement
more info
PubMed 
skeletal muscle satellite cell commitment IMP
Inferred from Mutant Phenotype
more info
PubMed 
skeletal muscle tissue development IMP
Inferred from Mutant Phenotype
more info
PubMed 
skeletal muscle tissue regeneration IMP
Inferred from Mutant Phenotype
more info
PubMed 
spinal cord association neuron differentiation IGI
Inferred from Genetic Interaction
more info
PubMed 
transcription from RNA polymerase II promoter IDA
Inferred from Direct Assay
more info
PubMed 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
transcription factor complex TAS
Traceable Author Statement
more info
PubMed 
Preferred Names
paired box protein Pax-7
Names
paired box protein Pax-7
paired box gene 7
paired box transcription factor PAX7

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011039.2NP_035169.1  paired box protein Pax-7

    See identical proteins and their annotated locations for NP_035169.1

    Status: VALIDATED

    Source sequence(s)
    AL831790, AL844480
    Consensus CDS
    CCDS18850.1
    UniProtKB/Swiss-Prot
    P47239
    Conserved Domains (3) summary
    pfam12360
    Location:345383
    Pax7; Paired box protein 7
    cd00086
    Location:216273
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
    cd00131
    Location:34161
    PAX; Paired Box domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000070.6 Reference GRCm38.p3 C57BL/6J

    Range
    139737059..139833026
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006538631.1XP_006538694.1  

    Related
    ENSMUSP00000030508, OTTMUSP00000010692, ENSMUST00000030508, OTTMUST00000023390
    Conserved Domains (4) summary
    pfam12360
    Location:344382
    Pax7; Paired box protein 7
    cd00086
    Location:215272
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
    cd00131
    Location:34160
    PAX; Paired Box domain
    pfam13551
    Location:56158
    HTH_29; Winged helix-turn helix
  2. XM_006538630.1XP_006538693.1  

    Conserved Domains (3) summary
    pfam12360
    Location:346384
    Pax7; Paired box protein 7
    cd00086
    Location:217274
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
    cd00131
    Location:34162
    PAX; Paired Box domain
  3. XM_006538629.1XP_006538692.1  

    UniProtKB/TrEMBL
    G3UX36
    Conserved Domains (3) summary
    pfam12360
    Location:347385
    Pax7; Paired box protein 7
    cd00086
    Location:218275
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
    cd00131
    Location:34163
    PAX; Paired Box domain

Alternate Mm_Celera

Genomic

  1. AC_000026.1 Alternate Mm_Celera

    Range
    141530711..141629332
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)