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Mib1 mindbomb homolog 1 (Drosophila) [ Mus musculus (house mouse) ]

Gene ID: 225164, updated on 8-Jul-2014
Official Symbol
Mib1provided by MGI
Official Full Name
mindbomb homolog 1 (Drosophila)provided by MGI
Primary source
MGI:2443157
See related
Ensembl:ENSMUSG00000024294
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Mib; DIP-1; mKIAA1323; E430019M12Rik
See Mib1 in Epigenomics, MapViewer
Location:
18 A1; 18
Exon count :
23
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 18 NC_000084.6 (10725625..10818578)

Chromosome 18 - NC_000084.6Genomic Context describing neighboring genes Neighboring gene abhydrolase domain containing 3 Neighboring gene RIKEN cDNA 4930563E18 gene Neighboring gene microRNA 133a-1 Neighboring gene microRNA 1a-2 Neighboring gene microRNA 1b Neighboring gene apurinic/apyrimidinic endonuclease 1 pseudogene Neighboring gene uncharacterized LOC102639517 Neighboring gene PHD finger protein 14 pseudogene

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity IEA
Inferred from Electronic Annotation
more info
 
coenzyme F420-0 gamma-glutamyl ligase activity IEA
Inferred from Electronic Annotation
more info
 
coenzyme F420-2 alpha-glutamyl ligase activity IEA
Inferred from Electronic Annotation
more info
 
ligase activity IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein-glutamic acid ligase activity IEA
Inferred from Electronic Annotation
more info
 
protein-glycine ligase activity IEA
Inferred from Electronic Annotation
more info
 
protein-glycine ligase activity, elongating IEA
Inferred from Electronic Annotation
more info
 
protein-glycine ligase activity, initiating IEA
Inferred from Electronic Annotation
more info
 
ribosomal S6-glutamic acid ligase activity IEA
Inferred from Electronic Annotation
more info
 
tubulin-glutamic acid ligase activity IEA
Inferred from Electronic Annotation
more info
 
tubulin-glycine ligase activity IEA
Inferred from Electronic Annotation
more info
 
ubiquitin-protein transferase activity IEA
Inferred from Electronic Annotation
more info
 
zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
Notch signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
blood vessel development IMP
Inferred from Mutant Phenotype
more info
PubMed 
heart development IMP
Inferred from Mutant Phenotype
more info
PubMed 
heart looping IMP
Inferred from Mutant Phenotype
more info
PubMed 
in utero embryonic development IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of neuron differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
neural tube formation IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of endocytosis IDA
Inferred from Direct Assay
more info
PubMed 
protein ubiquitination IEA
Inferred from Electronic Annotation
more info
 
somitogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
centrosome ISO
Inferred from Sequence Orthology
more info
 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytoplasmic vesicle IDA
Inferred from Direct Assay
more info
PubMed 
cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 
postsynaptic density ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
E3 ubiquitin-protein ligase MIB1
Names
E3 ubiquitin-protein ligase MIB1
mind bomb-1
skeletrophin
mind bomb homolog 1
DAPK-interacting protein 1
DAPK-interacting protein-1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_144860.2NP_659109.2  E3 ubiquitin-protein ligase MIB1

    See proteins identical to NP_659109.2

    Status: PROVISIONAL

    Source sequence(s)
    AY245539
    Consensus CDS
    CCDS29058.1
    UniProtKB/Swiss-Prot
    Q80SY4
    Related
    ENSMUSP00000131712, ENSMUST00000165555
    Conserved Domains (9) summary
    pfam06701
    Location:1574
    Blast Score: 262
    MIB_HERC2; Mib_herc2
    COG0666
    Location:494756
    Blast Score: 235
    Arp; FOG: Ankyrin repeat [General function prediction only]
    cd00162
    Location:962999
    Blast Score: 100
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably ...
    cd00204
    Location:524652
    Blast Score: 351
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd02339
    Location:83127
    Blast Score: 246
    ZZ_Mind_bomb; Zinc finger, ZZ type. Zinc finger present in Drosophila Mind bomb (D-mib) and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Mind bomb is an E3 ubiqitin ligase that has ...
    pfam13637
    Location:464517
    Blast Score: 102
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:450504
    Blast Score: 100
    Ank_5; Ankyrin repeats (many copies)
    pfam13920
    Location:864907
    Blast Score: 143
    zf-C3HC4_3; Zinc finger, C3HC4 type (RING finger)
    cl19548
    Location:301453
    Blast Score: 94
    DUF515; Protein of unknown function (DUF515)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000084.6 

    Range
    10725625..10818578
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006525810.1XP_006525873.1  

    See proteins identical to XP_006525873.1

    UniProtKB/Swiss-Prot
    Q80SY4
    Conserved Domains (9) summary
    pfam06701
    Location:1574
    Blast Score: 262
    MIB_HERC2; Mib_herc2
    COG0666
    Location:494756
    Blast Score: 235
    Arp; FOG: Ankyrin repeat [General function prediction only]
    cd00162
    Location:962999
    Blast Score: 100
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably ...
    cd00204
    Location:524652
    Blast Score: 351
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd02339
    Location:83127
    Blast Score: 246
    ZZ_Mind_bomb; Zinc finger, ZZ type. Zinc finger present in Drosophila Mind bomb (D-mib) and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Mind bomb is an E3 ubiqitin ligase that has ...
    pfam13637
    Location:464517
    Blast Score: 102
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:450504
    Blast Score: 100
    Ank_5; Ankyrin repeats (many copies)
    pfam13920
    Location:864907
    Blast Score: 143
    zf-C3HC4_3; Zinc finger, C3HC4 type (RING finger)
    cl19548
    Location:301453
    Blast Score: 94
    DUF515; Protein of unknown function (DUF515)
  2. XM_006525811.1XP_006525874.1  

    See proteins identical to XP_006525874.1

    UniProtKB/Swiss-Prot
    Q80SY4
    Conserved Domains (9) summary
    pfam06701
    Location:1574
    Blast Score: 262
    MIB_HERC2; Mib_herc2
    COG0666
    Location:494756
    Blast Score: 235
    Arp; FOG: Ankyrin repeat [General function prediction only]
    cd00162
    Location:962999
    Blast Score: 100
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably ...
    cd00204
    Location:524652
    Blast Score: 351
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd02339
    Location:83127
    Blast Score: 246
    ZZ_Mind_bomb; Zinc finger, ZZ type. Zinc finger present in Drosophila Mind bomb (D-mib) and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Mind bomb is an E3 ubiqitin ligase that has ...
    pfam13637
    Location:464517
    Blast Score: 102
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:450504
    Blast Score: 100
    Ank_5; Ankyrin repeats (many copies)
    pfam13920
    Location:864907
    Blast Score: 143
    zf-C3HC4_3; Zinc finger, C3HC4 type (RING finger)
    cl19548
    Location:301453
    Blast Score: 94
    DUF515; Protein of unknown function (DUF515)

Alternate Mm_Celera

Genomic

  1. AC_000040.1 

    Range
    10755617..10842201
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

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