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    Plvap plasmalemma vesicle associated protein [ Mus musculus (house mouse) ]

    Gene ID: 84094, updated on 28-Jun-2016
    Official Symbol
    Plvapprovided by MGI
    Official Full Name
    plasmalemma vesicle associated proteinprovided by MGI
    Primary source
    MGI:MGI:1890497
    See related
    Ensembl:ENSMUSG00000034845
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Pv1; MECA32
    Orthologs
    Location:
    8 B3.3; 8 34.43 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 8 NC_000074.6 (71497753..71511804, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (74021652..74035668, complement)

    Chromosome 8 - NC_000074.6Genomic Context describing neighboring genes Neighboring gene DET1 and DDB1 associated 1 Neighboring gene anoctamin 8 Neighboring gene GTP binding protein 3 Neighboring gene uncharacterized LOC108167534 Neighboring gene extensin-like Neighboring gene RIKEN cDNA C430049E01 gene Neighboring gene 14-3-3 protein sigma-like Neighboring gene bone marrow stromal cell antigen 2

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    MAPK cascade ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of cellular extravasation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of cellular extravasation ISO
    Inferred from Sequence Orthology
    more info
     
    tumor necrosis factor-mediated signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    caveola ISO
    Inferred from Sequence Orthology
    more info
     
    colocalizes_with caveola ISO
    Inferred from Sequence Orthology
    more info
     
    cell surface ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    extracellular exosome ISO
    Inferred from Sequence Orthology
    more info
     
    integral component of membrane ISO
    Inferred from Sequence Orthology
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    Preferred Names
    plasmalemma vesicle-associated protein
    Names
    MECA-32 antigen
    plasmalemma vesicle protein 1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_032398.2NP_115774.2  plasmalemma vesicle-associated protein

      See identical proteins and their annotated locations for NP_115774.2

      Status: VALIDATED

      Source sequence(s)
      AC127416, AF348403, AI225679, AV003733, BM898788
      Consensus CDS
      CCDS22396.1
      UniProtKB/Swiss-Prot
      Q91VC4
      UniProtKB/TrEMBL
      G3X924
      Related
      ENSMUSP00000035404, ENSMUST00000048452
      Conserved Domains (1) summary
      pfam06637
      Location:1438
      PV-1; PV-1 protein (PLVAP)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000074.6 Reference GRCm38.p4 C57BL/6J

      Range
      71497753..71511804 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011242342.1XP_011240644.1  

      Conserved Domains (1) summary
      pfam06637
      Location:1405
      PV-1; PV-1 protein (PLVAP)