Display Settings:

Format

Send to:

Choose Destination

Khk ketohexokinase [ Mus musculus (house mouse) ]

Gene ID: 16548, updated on 18-Apr-2015
Official Symbol
Khkprovided by MGI
Official Full Name
ketohexokinaseprovided by MGI
Primary source
MGI:MGI:1096353
See related
Ensembl:ENSMUSG00000029162; Vega:OTTMUSG00000030395
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Orthologs
See Khk in MapViewer
Location:
5 B1; 5 16.9 cM
Exon count:
9
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 5 NC_000071.6 (30921436..30931248)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (31224268..31233619)

Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene ATP/GTP binding protein-like 5 Neighboring gene oligosaccharyltransferase 4 homolog (S. cerevisiae) Neighboring gene elastin microfibril interfacer 1 Neighboring gene cell growth regulator with EF hand domain 1 Neighboring gene abhydrolase domain containing 1 Neighboring gene prolactin regulatory element binding

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
fructokinase activity ISO
Inferred from Sequence Orthology
more info
 
ketohexokinase activity IDA
Inferred from Direct Assay
more info
PubMed 
ketohexokinase activity ISO
Inferred from Sequence Orthology
more info
 
kinase activity IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 
carbohydrate phosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
carbohydrate phosphorylation ISO
Inferred from Sequence Orthology
more info
 
fructose metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
fructose metabolic process ISO
Inferred from Sequence Orthology
more info
 
phosphorylation IEA
Inferred from Electronic Annotation
more info
 
regulation of glycogen metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to glucose ISO
Inferred from Sequence Orthology
more info
 
response to insulin ISO
Inferred from Sequence Orthology
more info
 
response to sucrose ISO
Inferred from Sequence Orthology
more info
 
response to zinc ion ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
ketohexokinase
Names
ketohexokinase
hepatic fructokinase
NP_032465.2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_008439.3NP_032465.2  ketohexokinase

    See identical proteins and their annotated locations for NP_032465.2

    Status: PROVISIONAL

    Source sequence(s)
    AC109606
    Consensus CDS
    CCDS39050.1
    UniProtKB/Swiss-Prot
    P97328
    Related
    ENSMUSP00000114064, OTTMUSP00000039428, ENSMUST00000117435, OTTMUST00000075287
    Conserved Domains (1) summary
    cd01939
    Location:5295
    Ketohexokinase; Ketohexokinase (fructokinase, KHK) catalyzes the phosphorylation of fructose to fructose-1-phosphate (F1P), the first step in the metabolism of dietary fructose. KHK can also phosphorylate several other furanose sugars. It is found in higher eukaryotes ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000071.6 Reference GRCm38.p3 C57BL/6J

    Range
    30921436..30931248
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006503747.1XP_006503810.1  

    UniProtKB/TrEMBL
    E9Q1Q9
    Conserved Domains (1) summary
    cd01939
    Location:5340
    Ketohexokinase; Ketohexokinase (fructokinase, KHK) catalyzes the phosphorylation of fructose to fructose-1-phosphate (F1P), the first step in the metabolism of dietary fructose. KHK can also phosphorylate several other furanose sugars. It is found in higher eukaryotes ...
  2. XM_006503749.1XP_006503812.1  

    Conserved Domains (1) summary
    cd01939
    Location:5295
    Ketohexokinase; Ketohexokinase (fructokinase, KHK) catalyzes the phosphorylation of fructose to fructose-1-phosphate (F1P), the first step in the metabolism of dietary fructose. KHK can also phosphorylate several other furanose sugars. It is found in higher eukaryotes ...
  3. XM_006503748.1XP_006503811.1  

    Related
    ENSMUSP00000031053, OTTMUSP00000039427, ENSMUST00000031053, OTTMUST00000075286
    Conserved Domains (1) summary
    cd01939
    Location:5302
    Ketohexokinase; Ketohexokinase (fructokinase, KHK) catalyzes the phosphorylation of fructose to fructose-1-phosphate (F1P), the first step in the metabolism of dietary fructose. KHK can also phosphorylate several other furanose sugars. It is found in higher eukaryotes ...
  4. XM_006503750.1XP_006503813.1  

    See identical proteins and their annotated locations for XP_006503813.1

    Conserved Domains (1) summary
    cd01939
    Location:5250
    Ketohexokinase; Ketohexokinase (fructokinase, KHK) catalyzes the phosphorylation of fructose to fructose-1-phosphate (F1P), the first step in the metabolism of dietary fructose. KHK can also phosphorylate several other furanose sugars. It is found in higher eukaryotes ...

Alternate Mm_Celera

Genomic

  1. AC_000027.1 Alternate Mm_Celera

    Range
    28401689..28411041
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)