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Pez [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33882, updated on 7-Sep-2014
Official Symbol
Pezprovided by FlyBase
Primary source
FLYBASE:FBgn0031799
Locus tag
Dmel_CG9493
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster (old-lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG9493; Dmel\CG9493; dPez; PTPD1
Location:
26C3-26C3
Exon count:
8
Annotation release Status Assembly Chr Location
Release 6.01 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (6332881..6338671, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (6332881..6338671, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Discoidin domain receptor Neighboring gene CG13984 gene product from transcript CG13984-RA Neighboring gene PDZ domain-containing guanine nucleotide exchange factor Neighboring gene Cytochrome P450 reductase Neighboring gene CG9497 gene product from transcript CG9497-RB

Products Interactant Other Gene Complex Source Pubs Description

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
cytoskeletal protein binding ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
protein tyrosine phosphatase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
protein tyrosine phosphatase activity NAS
Non-traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
negative regulation of hippo signaling IGI
Inferred from Genetic Interaction
more info
 
negative regulation of stem cell proliferation IMP
Inferred from Mutant Phenotype
more info
 
protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
 
protein dephosphorylation NAS
Non-traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
apical part of cell IDA
Inferred from Direct Assay
more info
 
cell cortex IDA
Inferred from Direct Assay
more info
 
cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
CG9493 gene product from transcript CG9493-RB
Names
CG9493-PA
CG9493-PB
Pez
Pez-PA
Pez-PB
NP_001260127.1
NP_609013.1

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 

    Range
    6332881..6338671
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001273198.1NP_001260127.1  Pez, isoform B [Drosophila melanogaster]

    See proteins identical to NP_001260127.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9V3V3
    Related
    FBpp0303668, FBtr0331226
    Conserved Domains (6) summary
    smart00295
    Location:26230
    B41; Band 4.1 homologues
    cd00047
    Location:10091243
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    pfam00102
    Location:10071243
    Y_phosphatase; Protein-tyrosine phosphatase
    pfam00373
    Location:115230
    FERM_M; FERM central domain
    pfam09379
    Location:26108
    FERM_N; FERM N-terminal domain
    cl17171
    Location:206315
    PH-like; Pleckstrin homology-like domain
  2. NM_135169.3NP_609013.1  Pez, isoform A [Drosophila melanogaster]

    See proteins identical to NP_609013.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9V3V3
    Related
    FBpp0078914, FBtr0079284
    Conserved Domains (6) summary
    smart00295
    Location:26230
    B41; Band 4.1 homologues
    cd00047
    Location:10091243
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    pfam00102
    Location:10071243
    Y_phosphatase; Protein-tyrosine phosphatase
    pfam00373
    Location:115230
    FERM_M; FERM central domain
    pfam09379
    Location:26108
    FERM_N; FERM N-terminal domain
    cl17171
    Location:206315
    PH-like; Pleckstrin homology-like domain