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Mllt4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 [ Mus musculus (house mouse) ]

Gene ID: 17356, updated on 17-Mar-2015
Official Symbol
Mllt4provided by MGI
Official Full Name
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4provided by MGI
Primary source
MGI:MGI:1314653
See related
Ensembl:ENSMUSG00000068036; Vega:OTTMUSG00000029503
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AF6; Af-6; Gm314; Afadin; I-afadin; S-afadin; 5033403D15Rik
Orthologs
See Mllt4 in MapViewer
Location:
17; 17 A2
Exon count:
35
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 17 NC_000083.6 (13760541..13905798)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (13897548..14042801)

Chromosome 17 - NC_000083.6Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105246216 Neighboring gene uncharacterized LOC105246217 Neighboring gene t-complex-associated testis expressed 2 Neighboring gene predicted gene 7168 Neighboring gene predicted gene, 33889

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • Adherens junction, organism-specific biosystem (from KEGG)
    Adherens junction, organism-specific biosystemCell-cell adherens junctions (AJs), the most common type of intercellular adhesions, are important for maintaining tissue architecture and cell polarity and can limit cell movement and proliferation....
  • Adherens junction, conserved biosystem (from KEGG)
    Adherens junction, conserved biosystemCell-cell adherens junctions (AJs), the most common type of intercellular adhesions, are important for maintaining tissue architecture and cell polarity and can limit cell movement and proliferation....
  • Adherens junctions interactions, organism-specific biosystem (from REACTOME)
    Adherens junctions interactions, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • Cell junction organization, organism-specific biosystem (from REACTOME)
    Cell junction organization, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • Cell-Cell communication, organism-specific biosystem (from REACTOME)
    Cell-Cell communication, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • Cell-cell junction organization, organism-specific biosystem (from REACTOME)
    Cell-cell junction organization, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • Leukocyte transendothelial migration, organism-specific biosystem (from KEGG)
    Leukocyte transendothelial migration, organism-specific biosystemLeukocyte migaration from the blood into tissues is vital for immune surveillance and inflammation. During this diapedesis of leukocytes, the leukocytes bind to endothelial cell adhesion molecules (C...
  • Leukocyte transendothelial migration, conserved biosystem (from KEGG)
    Leukocyte transendothelial migration, conserved biosystemLeukocyte migaration from the blood into tissues is vital for immune surveillance and inflammation. During this diapedesis of leukocytes, the leukocytes bind to endothelial cell adhesion molecules (C...
  • Rap1 signaling pathway, organism-specific biosystem (from KEGG)
    Rap1 signaling pathway, organism-specific biosystemRap1 is a small GTPase that controls diverse processes, such as cell adhesion, cell-cell junction formation and cell polarity. Like all G proteins, Rap1 cycles between an inactive GDP-bound and an ac...
  • Rap1 signaling pathway, conserved biosystem (from KEGG)
    Rap1 signaling pathway, conserved biosystemRap1 is a small GTPase that controls diverse processes, such as cell adhesion, cell-cell junction formation and cell polarity. Like all G proteins, Rap1 cycles between an inactive GDP-bound and an ac...
  • Ras signaling pathway, organism-specific biosystem (from KEGG)
    Ras signaling pathway, organism-specific biosystemThe Ras proteins are GTPases that function as molecular switches for signaling pathways regulating cell proliferation, survival, growth, migration, differentiation or cytoskeletal dynamism. Ras prote...
  • Tight junction, organism-specific biosystem (from KEGG)
    Tight junction, organism-specific biosystemEpithelial tight junctions (TJs) are composed of at least three types of transmembrane protein -occludin, claudin and junctional adhesion molecules (JAMs)- and a cytoplasmic 'plaque' consisting of ma...
  • Tight junction, conserved biosystem (from KEGG)
    Tight junction, conserved biosystemEpithelial tight junctions (TJs) are composed of at least three types of transmembrane protein -occludin, claudin and junctional adhesion molecules (JAMs)- and a cytoplasmic 'plaque' consisting of ma...
  • cAMP signaling pathway, organism-specific biosystem (from KEGG)
    cAMP signaling pathway, organism-specific biosystemcAMP is one of the most common and universal second messengers, and its formation is promoted by adenylyl cyclase (AC) activation after ligation of G protein-coupled receptors (GPCRs) by ligands incl...
  • cAMP signaling pathway, conserved biosystem (from KEGG)
    cAMP signaling pathway, conserved biosystemcAMP is one of the most common and universal second messengers, and its formation is promoted by adenylyl cyclase (AC) activation after ligation of G protein-coupled receptors (GPCRs) by ligands incl...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
LIM domain binding ISO
Inferred from Sequence Orthology
more info
 
Ras GTPase binding ISO
Inferred from Sequence Orthology
more info
 
cell adhesion molecule binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
cell adhesion IEA
Inferred from Electronic Annotation
more info
 
establishment of endothelial intestinal barrier ISO
Inferred from Sequence Orthology
more info
 
positive regulation of GTPase activity ISO
Inferred from Sequence Orthology
more info
 
signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
adherens junction IDA
Inferred from Direct Assay
more info
PubMed 
apical part of cell IDA
Inferred from Direct Assay
more info
PubMed 
cell junction IDA
Inferred from Direct Assay
more info
PubMed 
cell junction ISO
Inferred from Sequence Orthology
more info
 
cell-cell adherens junction IDA
Inferred from Direct Assay
more info
PubMed 
cell-cell adherens junction ISO
Inferred from Sequence Orthology
more info
 
cell-cell junction IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
afadin
Names
afadin
myeloid/lymphoid or mixed lineage-leukemia translocation to 4 homolog
protein Af-6

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_010806.1NP_034936.1  afadin

    See proteins identical to NP_034936.1

    Status: VALIDATED

    Source sequence(s)
    AF172447, BI991173, BQ929757, BU611478, CB181965, CF538789, CJ165098, CK637291, CN529812, CN537179, CN538841, CO042367, CO433521
    Consensus CDS
    CCDS49955.1
    UniProtKB/Swiss-Prot
    Q9QZQ1
    Related
    ENSMUSP00000118318, OTTMUSP00000037863, ENSMUST00000139666, OTTMUST00000073195
    Conserved Domains (7) summary
    cd01781
    Location:247346
    AF6_RA_repeat2; Ubiquitin domain of AT-6, second repeat
    cd00060
    Location:417499
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:10071090
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam06098
    Location:15891650
    Radial_spoke_3; Radial spoke protein 3
    pfam11600
    Location:14801678
    CAF-1_p150; Chromatin assembly factor 1 complex p150 subunit, N-terminal
    cd15471
    Location:611932
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cl00155
    Location:20131
    UBQ; Ubiquitin-like proteins

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000083.6 Reference GRCm38.p3 C57BL/6J

    Range
    13760541..13905798
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006523752.2XP_006523815.1  

    Conserved Domains (6) summary
    pfam06936
    Location:15981712
    Selenoprotein_S; Selenoprotein S (SelS)
    cd01781
    Location:248347
    AF6_RA_repeat2; Ubiquitin domain of AT-6, second repeat
    cd01782
    Location:20132
    AF6_RA_repeat1; Ubiquitin domain of AT-6, first repeat
    cd00060
    Location:418500
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:10151098
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:612940
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
  2. XM_006523763.2XP_006523826.1  

    Conserved Domains (6) summary
    pfam06936
    Location:15981712
    Selenoprotein_S; Selenoprotein S (SelS)
    cd01781
    Location:248347
    AF6_RA_repeat2; Ubiquitin domain of AT-6, second repeat
    cd01782
    Location:20132
    AF6_RA_repeat1; Ubiquitin domain of AT-6, first repeat
    cd00060
    Location:418500
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:10151098
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:612940
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
  3. XM_006523755.2XP_006523818.1  

    Conserved Domains (6) summary
    pfam06936
    Location:15981711
    Selenoprotein_S; Selenoprotein S (SelS)
    cd01781
    Location:248347
    AF6_RA_repeat2; Ubiquitin domain of AT-6, second repeat
    cd01782
    Location:20132
    AF6_RA_repeat1; Ubiquitin domain of AT-6, first repeat
    cd00060
    Location:418500
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:10151098
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:612940
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
  4. XM_006523759.2XP_006523822.1  

    Conserved Domains (7) summary
    cd01781
    Location:248347
    AF6_RA_repeat2; Ubiquitin domain of AT-6, second repeat
    cd01782
    Location:20132
    AF6_RA_repeat1; Ubiquitin domain of AT-6, first repeat
    cd00060
    Location:418500
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:10151098
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam06098
    Location:15971658
    Radial_spoke_3; Radial spoke protein 3
    pfam11600
    Location:14881686
    CAF-1_p150; Chromatin assembly factor 1 complex p150 subunit, N-terminal
    cd15471
    Location:612940
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
  5. XM_006523764.2XP_006523827.1  

    Conserved Domains (7) summary
    cd01781
    Location:248347
    AF6_RA_repeat2; Ubiquitin domain of AT-6, second repeat
    cd01782
    Location:20132
    AF6_RA_repeat1; Ubiquitin domain of AT-6, first repeat
    cd00060
    Location:418500
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:10151098
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam06098
    Location:15971658
    Radial_spoke_3; Radial spoke protein 3
    pfam11600
    Location:14881686
    CAF-1_p150; Chromatin assembly factor 1 complex p150 subunit, N-terminal
    cd15471
    Location:612940
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
  6. XM_006523757.2XP_006523820.1  

    Conserved Domains (6) summary
    pfam06936
    Location:15911705
    Selenoprotein_S; Selenoprotein S (SelS)
    cd01781
    Location:248347
    AF6_RA_repeat2; Ubiquitin domain of AT-6, second repeat
    cd01782
    Location:20132
    AF6_RA_repeat1; Ubiquitin domain of AT-6, first repeat
    cd00060
    Location:418500
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:10081091
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:612933
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
  7. XM_006523766.2XP_006523829.1  

    Conserved Domains (6) summary
    pfam06936
    Location:15911705
    Selenoprotein_S; Selenoprotein S (SelS)
    cd01781
    Location:248347
    AF6_RA_repeat2; Ubiquitin domain of AT-6, second repeat
    cd01782
    Location:20132
    AF6_RA_repeat1; Ubiquitin domain of AT-6, first repeat
    cd00060
    Location:418500
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:10081091
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:612933
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
  8. XM_006523760.2XP_006523823.1  

    Conserved Domains (6) summary
    pfam06936
    Location:15831697
    Selenoprotein_S; Selenoprotein S (SelS)
    cd01781
    Location:248347
    AF6_RA_repeat2; Ubiquitin domain of AT-6, second repeat
    cd01782
    Location:20132
    AF6_RA_repeat1; Ubiquitin domain of AT-6, first repeat
    cd00060
    Location:385485
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:10001083
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:597925
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
  9. XM_006523754.2XP_006523817.1  

    Conserved Domains (6) summary
    pfam06936
    Location:15971711
    Selenoprotein_S; Selenoprotein S (SelS)
    cd01781
    Location:247346
    AF6_RA_repeat2; Ubiquitin domain of AT-6, second repeat
    cd01782
    Location:20132
    AF6_RA_repeat1; Ubiquitin domain of AT-6, first repeat
    cd00060
    Location:417499
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:10141097
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:611939
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
  10. XM_006523753.2XP_006523816.1  

    Conserved Domains (6) summary
    pfam06936
    Location:15971711
    Selenoprotein_S; Selenoprotein S (SelS)
    cd01781
    Location:247346
    AF6_RA_repeat2; Ubiquitin domain of AT-6, second repeat
    cd01782
    Location:20131
    AF6_RA_repeat1; Ubiquitin domain of AT-6, first repeat
    cd00060
    Location:417499
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:10141097
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:611939
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
  11. XM_006523765.2XP_006523828.1  

    UniProtKB/TrEMBL
    E9Q9C3
    Conserved Domains (7) summary
    cd01781
    Location:247346
    AF6_RA_repeat2; Ubiquitin domain of AT-6, second repeat
    cd00060
    Location:417499
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:10141097
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam06098
    Location:15961657
    Radial_spoke_3; Radial spoke protein 3
    pfam11600
    Location:14871685
    CAF-1_p150; Chromatin assembly factor 1 complex p150 subunit, N-terminal
    cd15471
    Location:611939
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cl00155
    Location:20131
    UBQ; Ubiquitin-like proteins
  12. XM_006523758.2XP_006523821.1  

    Conserved Domains (6) summary
    pfam06936
    Location:15901704
    Selenoprotein_S; Selenoprotein S (SelS)
    cd01781
    Location:247346
    AF6_RA_repeat2; Ubiquitin domain of AT-6, second repeat
    cd01782
    Location:20131
    AF6_RA_repeat1; Ubiquitin domain of AT-6, first repeat
    cd00060
    Location:417499
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:10071090
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:611932
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
  13. XM_006523756.2XP_006523819.1  

    Conserved Domains (6) summary
    pfam06936
    Location:15961710
    Selenoprotein_S; Selenoprotein S (SelS)
    cd01781
    Location:246345
    AF6_RA_repeat2; Ubiquitin domain of AT-6, second repeat
    cd01782
    Location:20131
    AF6_RA_repeat1; Ubiquitin domain of AT-6, first repeat
    cd00060
    Location:416498
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:10131096
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:610938
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
  14. XM_006523762.2XP_006523825.1  

    Conserved Domains (6) summary
    pfam06936
    Location:15741688
    Selenoprotein_S; Selenoprotein S (SelS)
    cd01781
    Location:246345
    AF6_RA_repeat2; Ubiquitin domain of AT-6, second repeat
    cd01782
    Location:20131
    AF6_RA_repeat1; Ubiquitin domain of AT-6, first repeat
    cd00060
    Location:383483
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:9911074
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:595916
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
  15. XM_006523767.2XP_006523830.1  

    Conserved Domains (7) summary
    cd01781
    Location:246345
    AF6_RA_repeat2; Ubiquitin domain of AT-6, second repeat
    cd01782
    Location:20131
    AF6_RA_repeat1; Ubiquitin domain of AT-6, first repeat
    cd00060
    Location:383483
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:9911074
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam06098
    Location:15731634
    Radial_spoke_3; Radial spoke protein 3
    pfam11600
    Location:14641662
    CAF-1_p150; Chromatin assembly factor 1 complex p150 subunit, N-terminal
    cd15471
    Location:595916
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin

RNA

  1. XR_385293.2 RNA Sequence

  2. XR_385294.2 RNA Sequence

Alternate Mm_Celera

Genomic

  1. AC_000039.1 Alternate Mm_Celera

    Range
    14558950..14705325
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)