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    Hrh4 histamine receptor H4 [ Mus musculus (house mouse) ]

    Gene ID: 225192, updated on 16-Jul-2016
    Official Symbol
    Hrh4provided by MGI
    Official Full Name
    histamine receptor H4provided by MGI
    Primary source
    MGI:MGI:2429635
    See related
    Ensembl:ENSMUSG00000037346
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    H4; H4R; BG26; HH4R; AXOR35; GPRv53; GPCR105
    Orthologs
    Location:
    18; 18 A1
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 18 NC_000084.6 (13006982..13023701)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 18 NC_000084.5 (13165499..13181391)

    Chromosome 18 - NC_000084.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 36490 Neighboring gene impact, RWD domain protein Neighboring gene ribosomal protein SA pseudogene Neighboring gene predicted gene, 36563

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Markers

    Homology

    Clone Names

    • MGC130500

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    G-protein coupled acetylcholine receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    G-protein coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    histamine receptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    histamine receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    signal transducer activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    G-protein coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    inflammatory response ISO
    Inferred from Sequence Orthology
    more info
     
    inflammatory response TAS
    Traceable Author Statement
    more info
    PubMed 
    phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    positive regulation of cytosolic calcium ion concentration IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of MAPK cascade IEA
    Inferred from Electronic Annotation
    more info
     
    signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    synaptic transmission, cholinergic IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of plasma membrane IC
    Inferred by Curator
    more info
    PubMed 
    membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    synapse IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_153087.2NP_694727.1  histamine H4 receptor

      See identical proteins and their annotated locations for NP_694727.1

      Status: VALIDATED

      Source sequence(s)
      AC131672
      Consensus CDS
      CCDS29069.1
      UniProtKB/Swiss-Prot
      Q91ZY2
      Related
      ENSMUSP00000041061, ENSMUST00000041676
      Conserved Domains (1) summary
      pfam00001
      Location:38360
      7tm_1; 7 transmembrane receptor (rhodopsin family)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000084.6 Reference GRCm38.p4 C57BL/6J

      Range
      13006982..13023701
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017317874.1XP_017173363.1  

      Conserved Domains (1) summary
      pfam00001
      Location:32119
      7tm_1; 7 transmembrane receptor (rhodopsin family)
    2. XM_006525817.2XP_006525880.1  

      See identical proteins and their annotated locations for XP_006525880.1

      UniProtKB/TrEMBL
      Q2M2N7
      Conserved Domains (1) summary
      pfam00001
      Location:157231
      7tm_1; 7 transmembrane receptor (rhodopsin family)