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    CAMK2B calcium/calmodulin-dependent protein kinase II beta [ Homo sapiens (human) ]

    Gene ID: 816, updated on 26-Jun-2015
    Official Symbol
    CAMK2Bprovided by HGNC
    Official Full Name
    calcium/calmodulin-dependent protein kinase II betaprovided by HGNC
    Primary source
    HGNC:HGNC:1461
    See related
    Ensembl:ENSG00000058404; HPRD:12127; MIM:607707; Vega:OTTHUMG00000023491
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    CAM2; CAMK2; CAMKB
    Summary
    The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
    Orthologs
    See CAMK2B in Epigenomics, MapViewer
    Location:
    7p14.3-p14.1
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    107 current GRCh38.p2 (GCF_000001405.28) 7 NC_000007.14 (44217150..44325994, complement)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (44256749..44365230, complement)

    Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105375257 Neighboring gene glucokinase (hexokinase 4) Neighboring gene YKT6 v-SNARE homolog (S. cerevisiae) Neighboring gene NudC domain containing 3 Neighboring gene ribosomal protein L32 pseudogene 18 Neighboring gene ribosomal protein L36a pseudogene 27

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    NHGRI GWAS Catalog

    Description
    A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip.
    NHGRI GWA Catalog
    Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.
    NHGRI GWA Catalog

    Protein interactions

    Protein Gene Interaction Pubs
    Tat tat Tat-induced IL-10 expression is regulated by p38 MAPK- and CaMK II-activated CREB-1 as well as Sp-1 transcription factors PubMed
    tat HIV-1 Tat inhibits the activation of CAMKII elicited via LFA-1 in NK cells, providing evidence that Tat inhibits NK cell activation which might contribute to the impairment of natural immunity in HIV-1 infection PubMed
    tat HIV-1 Tat inhibits the activation of CAMKII elicited via beta (3) integrin PubMed

    Go to the HIV-1, Human Interaction Database

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Clone Names

    • MGC29528

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    actin binding IEA
    Inferred from Electronic Annotation
    more info
     
    calmodulin binding IEA
    Inferred from Electronic Annotation
    more info
     
    calmodulin-dependent protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein homodimerization activity IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    G1/S transition of mitotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    activation of meiosis involved in egg activation IEA
    Inferred from Electronic Annotation
    more info
     
    calcium ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    cellular response to heat TAS
    Traceable Author Statement
    more info
     
    cytokine-mediated signaling pathway TAS
    Traceable Author Statement
    more info
     
    inhibitory G-protein coupled receptor phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    interferon-gamma-mediated signaling pathway TAS
    Traceable Author Statement
    more info
     
    neuromuscular process controlling balance IEA
    Inferred from Electronic Annotation
    more info
     
    peptidyl-serine phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of apoptotic signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of dendritic spine morphogenesis ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    positive regulation of neuron projection development ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    positive regulation of synapse maturation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    protein autophosphorylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein phosphorylation TAS
    Traceable Author Statement
    more info
    PubMed 
    regulation of calcium ion transport TAS
    Traceable Author Statement
    more info
    PubMed 
    regulation of cellular response to heat TAS
    Traceable Author Statement
    more info
     
    regulation of dendritic spine development TAS
    Traceable Author Statement
    more info
    PubMed 
    regulation of long-term neuronal synaptic plasticity TAS
    Traceable Author Statement
    more info
    PubMed 
    regulation of skeletal muscle adaptation TAS
    Traceable Author Statement
    more info
    PubMed 
    regulation of synapse structural plasticity TAS
    Traceable Author Statement
    more info
    PubMed 
    regulation of synaptic transmission, cholinergic IEA
    Inferred from Electronic Annotation
    more info
     
    response to cadmium ion IEA
    Inferred from Electronic Annotation
    more info
     
    signal transduction TAS
    Traceable Author Statement
    more info
    PubMed 
    synaptic transmission TAS
    Traceable Author Statement
    more info
     
    Component Evidence Code Pubs
    cytosol TAS
    Traceable Author Statement
    more info
     
    endocytic vesicle membrane TAS
    Traceable Author Statement
    more info
     
    microtubule organizing center IEA
    Inferred from Electronic Annotation
    more info
     
    neuronal postsynaptic density IEA
    Inferred from Electronic Annotation
    more info
     
    nucleoplasm TAS
    Traceable Author Statement
    more info
     
    plasma membrane TAS
    Traceable Author Statement
    more info
     
    sarcoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
     
    spindle midzone IEA
    Inferred from Electronic Annotation
    more info
     
    Preferred Names
    calcium/calmodulin-dependent protein kinase type II subunit beta
    Names
    calcium/calmodulin-dependent protein kinase type II subunit beta
    CaM kinase II beta subunit
    CaM-kinase II beta chain
    caMK-II subunit beta
    proline rich calmodulin-dependent protein kinase
    NP_001211.3
    NP_001280099.1
    NP_742075.1
    NP_742076.1
    NP_742077.1
    NP_742078.1
    NP_742079.1
    NP_742080.1
    NP_742081.1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_029407.1 RefSeqGene

      Range
      5001..113482
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001220.4NP_001211.3  calcium/calmodulin-dependent protein kinase type II subunit beta isoform 1

      See identical proteins and their annotated locations for NP_001211.3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
      Source sequence(s)
      AC006454, AK290148, BI550751, U23460
      Consensus CDS
      CCDS5483.1
      UniProtKB/TrEMBL
      A4D2J9
      UniProtKB/Swiss-Prot
      Q13554
      Related
      ENSP00000379098, OTTHUMP00000159355, ENST00000395749, OTTHUMT00000251138
      Conserved Domains (3) summary
      smart00220
      Location:14272
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      pfam08332
      Location:534661
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II Association
      cd14086
      Location:12303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
    2. NM_001293170.1NP_001280099.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform 2

      See identical proteins and their annotated locations for NP_001280099.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (9) lacks multiple alternate in-frame exons in the 3' coding region and differs in the 3' UTR, compared to variant 1. The encoded protein (isoform 2) is shorter than isoform 1. Variants 2 and 9 encode the same protein (isoform 2).
      Source sequence(s)
      AF078803, AK290148, AK294138, BI550751, BQ130578
      Consensus CDS
      CCDS5484.1
      UniProtKB/TrEMBL
      B7Z1Z6
      UniProtKB/Swiss-Prot
      Q13554
      Related
      ENSP00000326375, OTTHUMP00000209343, ENST00000350811, OTTHUMT00000343339
      Conserved Domains (3) summary
      smart00220
      Location:14272
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      pfam08332
      Location:410537
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II Association
      cd14086
      Location:12303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
    3. NM_172078.2NP_742075.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform 2

      See identical proteins and their annotated locations for NP_742075.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) lacks an in-frame segment of the coding region, compared to variant 1. It encodes a shorter isoform (2) that is missing an internal segment compared to isoform 1. Variants 2 and 9 encode the same protein (isoform 2).
      Source sequence(s)
      AC006454, AF078803, AK290148, BI550751
      Consensus CDS
      CCDS5484.1
      UniProtKB/Swiss-Prot
      Q13554
      Conserved Domains (3) summary
      smart00220
      Location:14272
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      pfam08332
      Location:410537
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II Association
      cd14086
      Location:12303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
    4. NM_172079.2NP_742076.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform 3

      See identical proteins and their annotated locations for NP_742076.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3), also known as beta 4, lacks an in-frame segment of the coding region, compared to variant 1. It encodes a shorter isoform (3), also known as beta 4 subunit, that is missing an internal segment compared to isoform 1.
      Source sequence(s)
      AC006454, AJ252238, AK290148, BI550751, BX445032, DB566810
      Consensus CDS
      CCDS5485.1
      UniProtKB/Swiss-Prot
      Q13554
      Related
      ENSP00000390292, ENST00000457475
      Conserved Domains (3) summary
      smart00220
      Location:14272
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      pfam08332
      Location:386513
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II Association
      cd14086
      Location:12303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
    5. NM_172080.2NP_742077.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform 4

      See identical proteins and their annotated locations for NP_742077.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4), also known as beta e, lacks an in-frame segment of the coding region, compared to variant 1. It encodes a shorter isoform (4), also known as beta e subunit, that is missing an internal segment compared to isoform 1.
      Source sequence(s)
      AC006454, AF083419, AK290148, BI550751
      Consensus CDS
      CCDS43573.1
      UniProtKB/Swiss-Prot
      Q13554
      Conserved Domains (3) summary
      smart00220
      Location:14272
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      pfam08332
      Location:385512
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II Association
      cd14086
      Location:12303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
    6. NM_172081.2NP_742078.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform 5

      See identical proteins and their annotated locations for NP_742078.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5), also known as beta e', lacks an in-frame segment of the coding region, compared to variant 1. It encodes a shorter isoform (5), also known as beta e' subunit, that is missing an internal segment compared to isoform 1.
      Source sequence(s)
      AC006454, AK290148, BC019070, BI550751
      Consensus CDS
      CCDS5486.1
      UniProtKB/Swiss-Prot
      Q13554
      Conserved Domains (3) summary
      smart00220
      Location:14272
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      pfam08332
      Location:371498
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II Association
      cd14086
      Location:12303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
    7. NM_172082.2NP_742079.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform 6

      See identical proteins and their annotated locations for NP_742079.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (6), also known as beta 6, lacks an in-frame segment of the coding region, compared to variant 1. It encodes a shorter isoform (6), also known as beta 6 subunit, that is missing an internal segment compared to isoform 1.
      Source sequence(s)
      AC006454, AF081924, AK290148, BI550751
      Consensus CDS
      CCDS5487.1
      UniProtKB/Swiss-Prot
      Q13554
      Conserved Domains (3) summary
      smart00220
      Location:14272
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14086
      Location:12303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      cl09109
      Location:386487
      NTF2_like; Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of ...
    8. NM_172083.2NP_742080.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform 7

      See identical proteins and their annotated locations for NP_742080.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (7), also known as beta 2, lacks an in-frame segment of the coding region, compared to variant 1. It encodes a shorter isoform (7), also known as beta 2 subunit, that is missing an internal segment compared to isoform 1.
      Source sequence(s)
      AA399393, AC006454, AJ252236, AK290148, BI550751, DA069361, DB175099
      Consensus CDS
      CCDS5488.1
      UniProtKB/Swiss-Prot
      Q13554
      Conserved Domains (3) summary
      smart00220
      Location:14272
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      pfam08332
      Location:347474
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II Association
      cd14086
      Location:12303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
    9. NM_172084.2NP_742081.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform 8

      See identical proteins and their annotated locations for NP_742081.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (8), also known as beta 7, lacks an in-frame segment of the coding region, compared to variant 1. It encodes a shorter isoform (8), also known as beta 7 subunit, that is missing an internal segment compared to isoform 1.
      Source sequence(s)
      AC006454, AK290148, BI550751, BX445032, DB566810
      Consensus CDS
      CCDS5489.1
      UniProtKB/Swiss-Prot
      Q13554
      Conserved Domains (3) summary
      smart00220
      Location:14272
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      pfam08332
      Location:317444
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II Association
      cd14086
      Location:12303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p2 Primary Assembly

    Genomic

    1. NC_000007.14 Reference GRCh38.p2 Primary Assembly

      Range
      44217150..44325994
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011515548.1XP_011513850.1  

      See identical proteins and their annotated locations for XP_011513850.1

      Conserved Domains (3) summary
      smart00220
      Location:14272
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      pfam08332
      Location:577704
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II Association
      cd14086
      Location:12303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
    2. XM_011515559.1XP_011513861.1  

      See identical proteins and their annotated locations for XP_011513861.1

      Conserved Domains (3) summary
      smart00220
      Location:1143
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      pfam08332
      Location:448575
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II Association
      cl21453
      Location:1174
      PKc_like; Protein Kinases, catalytic domain
    3. XM_011515557.1XP_011513859.1  

      Conserved Domains (3) summary
      smart00220
      Location:14272
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      pfam08332
      Location:528655
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II Association
      cd14086
      Location:12303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
    4. XM_006715781.2XP_006715844.1  

      Conserved Domains (3) summary
      smart00220
      Location:14272
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      pfam08332
      Location:494621
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II Association
      cd14086
      Location:12303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
    5. XM_011515554.1XP_011513856.1  

      Conserved Domains (3) summary
      smart00220
      Location:14272
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      pfam08332
      Location:537664
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II Association
      cd14086
      Location:12303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
    6. XM_011515552.1XP_011513854.1  

      Conserved Domains (3) summary
      smart00220
      Location:14272
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      pfam08332
      Location:552679
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II Association
      cd14086
      Location:12303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
    7. XM_005249864.3XP_005249921.1  

      See identical proteins and their annotated locations for XP_005249921.1

      Related
      ENSP00000326427, OTTHUMP00000159442, ENST00000353625, OTTHUMT00000251231
      Conserved Domains (3) summary
      smart00220
      Location:14272
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      pfam08332
      Location:362489
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II Association
      cd14086
      Location:12303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
    8. XM_011515556.1XP_011513858.1  

      Conserved Domains (3) summary
      smart00220
      Location:14272
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      pfam08332
      Location:529656
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II Association
      cd14086
      Location:12303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
    9. XM_011515550.1XP_011513852.1  

      Conserved Domains (3) summary
      smart00220
      Location:14272
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      pfam08332
      Location:553680
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II Association
      cd14086
      Location:12303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
    10. XM_006715784.2XP_006715847.1  

      See identical proteins and their annotated locations for XP_006715847.1

      Related
      ENSP00000326544, OTTHUMP00000159441, ENST00000347193, OTTHUMT00000251230
      Conserved Domains (3) summary
      smart00220
      Location:14272
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      pfam08332
      Location:386513
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II Association
      cd14086
      Location:12303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
    11. XM_011515551.1XP_011513853.1  

      Conserved Domains (3) summary
      smart00220
      Location:14272
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      pfam08332
      Location:553680
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II Association
      cd14086
      Location:12303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
    12. XM_005249862.3XP_005249919.1  

      See identical proteins and their annotated locations for XP_005249919.1

      Related
      ENSP00000397937, OTTHUMP00000025109, ENST00000440254, OTTHUMT00000059812
      Conserved Domains (3) summary
      smart00220
      Location:14272
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      pfam08332
      Location:395522
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II Association
      cd14086
      Location:12303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
    13. XM_011515549.1XP_011513851.1  

      Conserved Domains (3) summary
      smart00220
      Location:14272
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      pfam08332
      Location:562689
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II Association
      cd14086
      Location:12303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
    14. XM_011515553.1XP_011513855.1  

      Conserved Domains (3) summary
      smart00220
      Location:14272
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      pfam08332
      Location:539666
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II Association
      cd14086
      Location:12303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
    15. XM_011515555.1XP_011513857.1  

      Conserved Domains (3) summary
      smart00220
      Location:14272
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      pfam08332
      Location:534661
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II Association
      cd14086
      Location:12303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
    16. XM_011515547.1XP_011513849.1  

      See identical proteins and their annotated locations for XP_011513849.1

      Conserved Domains (3) summary
      smart00220
      Location:14272
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      pfam08332
      Location:577704
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II Association
      cd14086
      Location:12303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
    17. XM_011515560.1XP_011513862.1  

      See identical proteins and their annotated locations for XP_011513862.1

      Conserved Domains (3) summary
      smart00220
      Location:1143
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      pfam08332
      Location:448575
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II Association
      cl21453
      Location:1174
      PKc_like; Protein Kinases, catalytic domain
    18. XM_011515558.1XP_011513860.1  

      Conserved Domains (2) summary
      smart00220
      Location:14272
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14086
      Location:12303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

    Alternate CHM1_1.1

    Genomic

    1. NC_018918.2 Alternate CHM1_1.1

      Range
      44260608..44369178
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)