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Morf4l1 mortality factor 4 like 1 [ Mus musculus (house mouse) ]

Gene ID: 21761, updated on 8-Dec-2014
Official Symbol
Morf4l1provided by MGI
Official Full Name
mortality factor 4 like 1provided by MGI
Primary source
MGI:MGI:1096551
See related
Ensembl:ENSMUSG00000062270; Vega:OTTMUSG00000046589
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
MRG15; Tex189; TEG-189; MORFRG15; mKIAA4002
See Morf4l1 in Epigenomics, MapViewer
Location:
9; 9 D1
Exon count:
13
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 9 NC_000075.6 (90091669..90114820, complement)

Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene thymidine kinase 1 pseudogene Neighboring gene cathepsin H Neighboring gene transmembrane protein 41B pseudogene Neighboring gene nuclear encoded tRNA lysine 18 (anticodon CTT)

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
Products Interactant Other Gene Complex Source Pubs Description

Homology

Clone Names

  • KIAA4002, MGC102415, MGC103105, MGC118047

Gene Ontology Provided by MGI

Function Evidence Code Pubs
chromatin binding IDA
Inferred from Direct Assay
more info
PubMed 
protein N-terminus binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
DNA recombination IEA
Inferred from Electronic Annotation
more info
 
DNA repair IEA
Inferred from Electronic Annotation
more info
 
cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
cellular response to DNA damage stimulus IEA
Inferred from Electronic Annotation
more info
 
chromatin modification IEA
Inferred from Electronic Annotation
more info
 
chromatin remodeling TAS
Traceable Author Statement
more info
PubMed 
double-strand break repair via homologous recombination ISO
Inferred from Sequence Orthology
more info
 
histone H2A acetylation ISO
Inferred from Sequence Orthology
more info
 
histone H4 acetylation ISO
Inferred from Sequence Orthology
more info
 
histone deacetylation ISO
Inferred from Sequence Orthology
more info
 
regulation of growth IEA
Inferred from Electronic Annotation
more info
 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
NuA4 histone acetyltransferase complex ISO
Inferred from Sequence Orthology
more info
 
Sin3 complex ISO
Inferred from Sequence Orthology
more info
 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
mortality factor 4-like protein 1
Names
mortality factor 4-like protein 1
testis expressed gene 189
MORF-related gene 15 protein
testis-expressed gene 189 protein
transcription factor-like protein MRG15

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001039147.2NP_001034236.1  mortality factor 4-like protein 1 isoform a

    See proteins identical to NP_001034236.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
    Source sequence(s)
    AC140392, BC085103
    Consensus CDS
    CCDS23400.1
    UniProtKB/Swiss-Prot
    P60762
    Related
    ENSMUSP00000082346, OTTMUSP00000066856, ENSMUST00000085248, OTTMUST00000121135
    Conserved Domains (2) summary
    pfam05712
    Location:168350
    MRG; MRG
    pfam11717
    Location:11103
    Tudor-knot; RNA binding activity-knot of a chromodomain
  2. NM_024431.3NP_077751.1  mortality factor 4-like protein 1 isoform b

    See proteins identical to NP_077751.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a.
    Source sequence(s)
    AC140392, AK167079, BC085103
    Consensus CDS
    CCDS52885.1
    UniProtKB/Swiss-Prot
    P60762
    UniProtKB/TrEMBL
    Q569V4
    Related
    ENSMUSP00000132020, OTTMUSP00000066857, ENSMUST00000169860, OTTMUST00000121136
    Conserved Domains (2) summary
    cd00024
    Location:3078
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    pfam05712
    Location:129311
    MRG; MRG

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000075.6 

    Range
    90091669..90114820
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006511018.1XP_006511081.1  

    Conserved Domains (2) summary
    pfam05712
    Location:167349
    MRG; MRG
    pfam11717
    Location:11102
    Tudor-knot; RNA binding activity-knot of a chromodomain

Alternate Mm_Celera

Genomic

  1. AC_000031.1 

    Range
    89707212..89730327
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)