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Rap1a RAS-related protein-1a [ Mus musculus (house mouse) ]

Gene ID: 109905, updated on 19-Jul-2014
Official Symbol
Rap1aprovided by MGI
Official Full Name
RAS-related protein-1aprovided by MGI
Primary source
MGI:97852
See related
Ensembl:ENSMUSG00000068798
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Rap1; G-22K; Krev-1; AI848598
See Rap1a in Epigenomics, MapViewer
Location:
3 F2.2; 3 46.45 cM
Exon count:
10
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 3 NC_000069.6 (105727260..105801381, complement)

Chromosome 3 - NC_000069.6Genomic Context describing neighboring genes Neighboring gene DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 Neighboring gene family with sequence similarity 212, member B Neighboring gene uncharacterized LOC102638336 Neighboring gene predicted gene 5547

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • MGC102329

Gene Ontology Provided by MGI

Function Evidence Code Pubs
GTP binding IEA
Inferred from Electronic Annotation
more info
 
GTPase activity IDA
Inferred from Direct Assay
more info
PubMed 
Rap guanyl-nucleotide exchange factor activity ISO
Inferred from Sequence Orthology
more info
 
Ras GTPase binding IPI
Inferred from Physical Interaction
more info
PubMed 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein complex binding ISO
Inferred from Sequence Orthology
more info
 
protein transporter activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
GTP catabolic process IDA
Inferred from Direct Assay
more info
PubMed 
Rap protein signal transduction ISO
Inferred from Sequence Orthology
more info
 
cellular response to cAMP ISO
Inferred from Sequence Orthology
more info
 
cellular response to nerve growth factor stimulus ISO
Inferred from Sequence Orthology
more info
 
establishment of endothelial barrier ISO
Inferred from Sequence Orthology
more info
 
negative regulation of synaptic vesicle exocytosis IGI
Inferred from Genetic Interaction
more info
 
nerve growth factor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
nervous system development IEA
Inferred from Electronic Annotation
more info
 
positive regulation of ERK1 and ERK2 cascade IGI
Inferred from Genetic Interaction
more info
 
positive regulation of ERK1 and ERK2 cascade ISO
Inferred from Sequence Orthology
more info
 
positive regulation of Rap GTPase activity ISO
Inferred from Sequence Orthology
more info
 
positive regulation of neuron projection development IDA
Inferred from Direct Assay
more info
 
positive regulation of neuron projection development ISO
Inferred from Sequence Orthology
more info
 
positive regulation of protein kinase activity ISO
Inferred from Sequence Orthology
more info
 
positive regulation of vasculogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein transport ISO
Inferred from Sequence Orthology
more info
 
regulation of cell junction assembly ISO
Inferred from Sequence Orthology
more info
 
signal transduction IEA
Inferred from Electronic Annotation
more info
 
small GTPase mediated signal transduction IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
cell junction IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
early endosome ISO
Inferred from Sequence Orthology
more info
 
endosome IEA
Inferred from Electronic Annotation
more info
 
extracellular vesicular exosome ISO
Inferred from Sequence Orthology
more info
 
guanyl-nucleotide exchange factor complex IDA
Inferred from Direct Assay
more info
PubMed 
late endosome ISO
Inferred from Sequence Orthology
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
neuron projection IDA
Inferred from Direct Assay
more info
 
perinuclear region of cytoplasm ISO
Inferred from Sequence Orthology
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
ras-related protein Rap-1A
Names
ras-related protein Rap-1A
ras-related protein Krev-1
GTP-binding protein SMG-P21A

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_145541.5NP_663516.1  ras-related protein Rap-1A precursor

    See proteins identical to NP_663516.1

    Status: VALIDATED

    Source sequence(s)
    AA210264, AC139316, AK030897, AK152504, CX206795
    Consensus CDS
    CCDS17711.1
    UniProtKB/Swiss-Prot
    P62835
    UniProtKB/TrEMBL
    Q3U7U8
    UniProtKB/TrEMBL
    Q3V3W9
    Related
    ENSMUSP00000088174, ENSMUST00000090678
    Conserved Domains (1) summary
    cd04175
    Location:3167
    Blast Score: 879
    Rap1; Rap1 family GTPase consists of Rap1a and Rap1b isoforms

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000069.6 

    Range
    105727260..105801381
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006500907.1XP_006500970.1  

    See proteins identical to XP_006500970.1

    UniProtKB/Swiss-Prot
    P62835
    Conserved Domains (1) summary
    cd04175
    Location:3167
    Blast Score: 879
    Rap1; Rap1 family GTPase consists of Rap1a and Rap1b isoforms

RNA

  1. XR_375476.1 RNA Sequence

Alternate Mm_Celera

Genomic

  1. AC_000025.1 

    Range
    107916214..107990297
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)