Display Settings:

Format

Send to:

Choose Destination

Gata2 GATA binding protein 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 25159, updated on 13-Jan-2015
Official Symbol
Gata2provided by RGD
Official Full Name
GATA binding protein 2provided by RGD
Primary source
RGD:2664
See related
Ensembl:ENSRNOG00000012347
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus
Summary
mediates phagocytosis function of alveolar macrophages [RGD, Feb 2006]
Orthologs
See Gata2 in MapViewer
Location:
4q34-q41
Exon count:
7
Annotation release Status Assembly Chr Location
105 current Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (120133713..120142488)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 4 NC_005103.3 (185369926..185383944)

Chromosome 4 - NC_005103.4Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103692180 Neighboring gene uncharacterized LOC102554068 Neighboring gene DnaJ (Hsp40) homolog, subfamily B, member 8 Neighboring gene t-complex protein 1, pseudogene 1

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
C2H2 zinc finger domain binding IEA
Inferred from Electronic Annotation
more info
 
C2H2 zinc finger domain binding ISO
Inferred from Sequence Orthology
more info
 
DNA binding ISO
Inferred from Sequence Orthology
more info
 
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription IEA
Inferred from Electronic Annotation
more info
 
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription ISO
Inferred from Sequence Orthology
more info
 
RNA polymerase II distal enhancer sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
RNA polymerase II distal enhancer sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
chromatin binding IEA
Inferred from Electronic Annotation
more info
 
chromatin binding ISO
Inferred from Sequence Orthology
more info
 
enhancer sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
sequence-specific DNA binding transcription factor activity ISO
Inferred from Sequence Orthology
more info
 
transcription factor binding IEA
Inferred from Electronic Annotation
more info
 
transcription factor binding ISO
Inferred from Sequence Orthology
more info
 
zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
GABAergic neuron differentiation IEA
Inferred from Electronic Annotation
more info
 
GABAergic neuron differentiation ISO
Inferred from Sequence Orthology
more info
 
cell differentiation ISO
Inferred from Sequence Orthology
more info
 
cell differentiation in hindbrain IEA
Inferred from Electronic Annotation
more info
 
cell differentiation in hindbrain ISO
Inferred from Sequence Orthology
more info
 
cell fate determination IEA
Inferred from Electronic Annotation
more info
 
cell fate determination ISO
Inferred from Sequence Orthology
more info
 
cell maturation IEA
Inferred from Electronic Annotation
more info
 
cell maturation ISO
Inferred from Sequence Orthology
more info
 
central nervous system neuron development IEA
Inferred from Electronic Annotation
more info
 
central nervous system neuron development ISO
Inferred from Sequence Orthology
more info
 
commitment of neuronal cell to specific neuron type in forebrain IEA
Inferred from Electronic Annotation
more info
 
commitment of neuronal cell to specific neuron type in forebrain ISO
Inferred from Sequence Orthology
more info
 
definitive hemopoiesis IEA
Inferred from Electronic Annotation
more info
 
definitive hemopoiesis ISO
Inferred from Sequence Orthology
more info
 
embryonic placenta development IEA
Inferred from Electronic Annotation
more info
 
embryonic placenta development ISO
Inferred from Sequence Orthology
more info
 
eosinophil fate commitment IEA
Inferred from Electronic Annotation
more info
 
eosinophil fate commitment ISO
Inferred from Sequence Orthology
more info
 
homeostasis of number of cells within a tissue IEA
Inferred from Electronic Annotation
more info
 
homeostasis of number of cells within a tissue ISO
Inferred from Sequence Orthology
more info
 
inner ear morphogenesis IEA
Inferred from Electronic Annotation
more info
 
inner ear morphogenesis ISO
Inferred from Sequence Orthology
more info
 
mast cell degranulation IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of Notch signaling pathway IEA
Inferred from Electronic Annotation
more info
 
negative regulation of Notch signaling pathway ISO
Inferred from Sequence Orthology
more info
 
negative regulation of fat cell differentiation IEA
Inferred from Electronic Annotation
more info
 
negative regulation of fat cell differentiation ISO
Inferred from Sequence Orthology
more info
 
negative regulation of fat cell proliferation IEA
Inferred from Electronic Annotation
more info
 
negative regulation of fat cell proliferation ISO
Inferred from Sequence Orthology
more info
 
negative regulation of macrophage differentiation IEA
Inferred from Electronic Annotation
more info
 
negative regulation of macrophage differentiation ISO
Inferred from Sequence Orthology
more info
 
negative regulation of myeloid cell differentiation ISO
Inferred from Sequence Orthology
more info
 
negative regulation of neural precursor cell proliferation IEA
Inferred from Electronic Annotation
more info
 
negative regulation of neural precursor cell proliferation ISO
Inferred from Sequence Orthology
more info
 
negative regulation of transcription from RNA polymerase II promoter IEA
Inferred from Electronic Annotation
more info
 
negative regulation of transcription from RNA polymerase II promoter ISO
Inferred from Sequence Orthology
more info
 
neuron differentiation ISO
Inferred from Sequence Orthology
more info
 
neuron fate commitment ISO
Inferred from Sequence Orthology
more info
 
neuron migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
phagocytosis IEA
Inferred from Electronic Annotation
more info
 
pituitary gland development IEA
Inferred from Electronic Annotation
more info
 
pituitary gland development ISO
Inferred from Sequence Orthology
more info
 
positive regulation of angiogenesis IEA
Inferred from Electronic Annotation
more info
 
positive regulation of angiogenesis ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cytosolic calcium ion concentration IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of erythrocyte differentiation IEA
Inferred from Electronic Annotation
more info
 
positive regulation of erythrocyte differentiation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of megakaryocyte differentiation IEA
Inferred from Electronic Annotation
more info
 
positive regulation of megakaryocyte differentiation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of neuron differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of phagocytosis IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of phagocytosis, engulfment IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of transcription from RNA polymerase II promoter IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of transcription from RNA polymerase II promoter ISO
Inferred from Sequence Orthology
more info
 
regulation of forebrain neuron differentiation IEA
Inferred from Electronic Annotation
more info
 
regulation of forebrain neuron differentiation ISO
Inferred from Sequence Orthology
more info
 
regulation of histone acetylation IEA
Inferred from Electronic Annotation
more info
 
regulation of histone acetylation ISO
Inferred from Sequence Orthology
more info
 
response to lipid IEP
Inferred from Expression Pattern
more info
PubMed 
semicircular canal development IEA
Inferred from Electronic Annotation
more info
 
semicircular canal development ISO
Inferred from Sequence Orthology
more info
 
somatic stem cell maintenance IEA
Inferred from Electronic Annotation
more info
 
somatic stem cell maintenance ISO
Inferred from Sequence Orthology
more info
 
transcription from RNA polymerase II promoter ISO
Inferred from Sequence Orthology
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
transcription, DNA-templated ISO
Inferred from Sequence Orthology
more info
 
urogenital system development IEA
Inferred from Electronic Annotation
more info
 
urogenital system development ISO
Inferred from Sequence Orthology
more info
 
ventral spinal cord interneuron differentiation IEA
Inferred from Electronic Annotation
more info
 
ventral spinal cord interneuron differentiation ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
mast cell granule IMP
Inferred from Mutant Phenotype
more info
PubMed 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus ISO
Inferred from Sequence Orthology
more info
 
protein complex IEA
Inferred from Electronic Annotation
more info
 
protein complex ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
endothelial transcription factor GATA-2
Names
endothelial transcription factor GATA-2
GATA-binding protein 2
GATA-bindning protein 2
gata2 {ECO:0000312|EMBL:AAK51128.1}

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_033442.1NP_254277.1  endothelial transcription factor GATA-2

    See proteins identical to NP_254277.1

    Status: PROVISIONAL

    Source sequence(s)
    AY032734
    UniProtKB/TrEMBL
    B2DBE1
    UniProtKB/Swiss-Prot
    Q924Y4
    Related
    ENSRNOP00000017240, ENSRNOT00000017240
    Conserved Domains (1) summary
    cd00202
    Location:349398
    ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 105

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005103.4 

    Range
    120133713..120142488
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Rn_Celera

Genomic

  1. AC_000072.1 

    Range
    109615354..109624129
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)