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    Hcrtr2 hypocretin (orexin) receptor 2 [ Mus musculus (house mouse) ]

    Gene ID: 387285, updated on 4-Jul-2015
    Official Symbol
    Hcrtr2provided by MGI
    Official Full Name
    hypocretin (orexin) receptor 2provided by MGI
    Primary source
    MGI:MGI:2680765
    See related
    Ensembl:ENSMUSG00000032360; Vega:OTTMUSG00000044825
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    OX2R; mOXR2; mOX2aR; mOX2bR
    Orthologs
    See Hcrtr2 in Epigenomics, MapViewer
    Location:
    9; 9 D
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    105 current GRCm38.p3 (GCF_000001635.23) 9 NC_000075.6 (76225880..76323868, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (76073687..76171385, complement)

    Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase-like 1 Neighboring gene GDNF family receptor alpha like Neighboring gene family with sequence similarity 83, member B Neighboring gene predicted gene, 34158

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    G-protein coupled receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    neuropeptide receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    orexin receptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    orexin receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    peptide binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    peptide hormone binding ISO
    Inferred from Sequence Orthology
    more info
     
    signal transducer activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    G-protein coupled receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to hormone stimulus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    circadian sleep/wake cycle process IEA
    Inferred from Electronic Annotation
    more info
     
    feeding behavior IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    feeding behavior ISO
    Inferred from Sequence Orthology
    more info
     
    neuropeptide signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    neuropeptide signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    phospholipase C-activating G-protein coupled receptor signaling pathway IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of circadian sleep/wake cycle, sleep IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    response to peptide IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    synaptic transmission IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    Preferred Names
    orexin receptor type 2
    Names
    hypocretin receptor type 2
    ox-2-R
    ox2-R

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_198962.3NP_945200.1  orexin receptor type 2

      See identical proteins and their annotated locations for NP_945200.1

      Status: PROVISIONAL

      Source sequence(s)
      AC140311
      Consensus CDS
      CCDS23350.1
      UniProtKB/Swiss-Prot
      P58308
      Related
      ENSMUSP00000058230, OTTMUSP00000065830, ENSMUST00000063140, OTTMUST00000117816
      Conserved Domains (3) summary
      pfam03827
      Location:383443
      Orexin_rec2; Orexin receptor type 2
      pfam00001
      Location:77364
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      pfam10328
      Location:65185
      7TM_GPCR_Srx; Serpentine type 7TM GPCR chemoreceptor Srx

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p3 C57BL/6J

    Genomic

    1. NC_000075.6 Reference GRCm38.p3 C57BL/6J

      Range
      76225880..76323868
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011242766.1XP_011241068.1  

      See identical proteins and their annotated locations for XP_011241068.1

      Conserved Domains (3) summary
      pfam03827
      Location:383443
      Orexin_rec2; Orexin receptor type 2
      pfam00001
      Location:77364
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:65185
      7tm_4; Olfactory receptor

    Alternate Mm_Celera

    Genomic

    1. AC_000031.1 Alternate Mm_Celera

      Range
      73390040..73487756
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)