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AZGP1 alpha-2-glycoprotein 1, zinc-binding [ Homo sapiens (human) ]

Gene ID: 563, updated on 19-Mar-2015
Official Symbol
AZGP1provided by HGNC
Official Full Name
alpha-2-glycoprotein 1, zinc-bindingprovided by HGNC
Primary source
HGNC:HGNC:910
See related
Ensembl:ENSG00000160862; HPRD:01910; MIM:194460; Vega:OTTHUMG00000023066
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ZAG; ZA2G
Orthologs
See AZGP1 in MapViewer
Location:
7q22.1
Exon count:
4
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 7 NC_000007.14 (99966727..99976112, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (99564350..99573735, complement)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene tripartite motif containing 4 Neighboring gene uncharacterized LOC101927610 Neighboring gene gap junction protein, gamma 3, 30.2kDa Neighboring gene alpha-2-glycoprotein 1, zinc-binding pseudogene 1 Neighboring gene gap junction protein, gamma 3, 30.2kDa pseudogene

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
antigen binding IBA
Inferred from Biological aspect of Ancestor
more info
 
glycoprotein binding IPI
Inferred from Physical Interaction
more info
PubMed 
peptide antigen binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein transmembrane transporter activity NAS
Non-traceable Author Statement
more info
PubMed 
ribonuclease activity NAS
Non-traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
RNA phosphodiester bond hydrolysis NAS
Non-traceable Author Statement
more info
PubMed 
antigen processing and presentation IBA
Inferred from Biological aspect of Ancestor
more info
 
antigen processing and presentation of peptide antigen via MHC class I IEA
Inferred from Electronic Annotation
more info
 
cell adhesion IDA
Inferred from Direct Assay
more info
PubMed 
cell adhesion ISS
Inferred from Sequence or Structural Similarity
more info
 
detection of chemical stimulus involved in sensory perception of bitter taste IDA
Inferred from Direct Assay
more info
PubMed 
immune response IEA
Inferred from Electronic Annotation
more info
 
negative regulation of cell proliferation NAS
Non-traceable Author Statement
more info
PubMed 
positive regulation of T cell mediated cytotoxicity IEA
Inferred from Electronic Annotation
more info
 
protein transmembrane transport NAS
Non-traceable Author Statement
more info
PubMed 
retina homeostasis IEP
Inferred from Expression Pattern
more info
PubMed 
Component Evidence Code Pubs
MHC class I protein complex IEA
Inferred from Electronic Annotation
more info
 
extracellular exosome IDA
Inferred from Direct Assay
more info
PubMed 
extracellular region NAS
Non-traceable Author Statement
more info
PubMed 
extracellular space IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
Preferred Names
zinc-alpha-2-glycoprotein
Names
zinc-alpha-2-glycoprotein
Alpha-2-glycoprotein, zinc
Zn-alpha2-glycoprotein
zn-alpha-2-GP
zn-alpha-2-glycoprotein

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001185.3NP_001176.1  zinc-alpha-2-glycoprotein precursor

    See proteins identical to NP_001176.1

    Status: VALIDATED

    Source sequence(s)
    AW015837, BC005306, BC033830, CB148270
    Consensus CDS
    CCDS5680.1
    UniProtKB/Swiss-Prot
    P25311
    Related
    ENSP00000292401, OTTHUMP00000024684, ENST00000292401, OTTHUMT00000059387
    Conserved Domains (2) summary
    cd07698
    Location:205296
    IgC_MHC_I_alpha3; Class I major histocompatibility complex (MHC) alpha chain immunoglobulin domain
    pfam00129
    Location:26201
    MHC_I; Class I Histocompatibility antigen, domains alpha 1 and 2

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p2 Primary Assembly

    Range
    99966727..99976112
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018918.2 Alternate CHM1_1.1

    Range
    99494515..99503901
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)