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Drd5 dopamine receptor D5 [ Mus musculus (house mouse) ]

Gene ID: 13492, updated on 19-Sep-2014
Official Symbol
Drd5provided by MGI
Official Full Name
dopamine receptor D5provided by MGI
Primary source
MGI:MGI:94927
See related
Ensembl:ENSMUSG00000039358
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
D5R; Drd-5; Drd1b; Gpcr1
See Drd5 in Epigenomics, MapViewer
Location:
5 B3; 5 20.4 cM
Exon count:
1
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 5 NC_000071.6 (38319509..38322310)

Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene otopetrin 1 Neighboring gene uncharacterized LOC102637363 Neighboring gene uncharacterized LOC102637436 Neighboring gene RIKEN cDNA 4930487D11 gene Neighboring gene solute carrier family 2 (facilitated glucose transporter), member 9

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
G-protein alpha-subunit binding ISO
Inferred from Sequence Orthology
more info
 
G-protein coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
dopamine binding ISO
Inferred from Sequence Orthology
more info
 
dopamine neurotransmitter receptor activity ISO
Inferred from Sequence Orthology
more info
 
dopamine neurotransmitter receptor activity, coupled via Gs IDA
Inferred from Direct Assay
more info
PubMed 
dopamine neurotransmitter receptor activity, coupled via Gs IMP
Inferred from Mutant Phenotype
more info
PubMed 
dopamine neurotransmitter receptor activity, coupled via Gs ISO
Inferred from Sequence Orthology
more info
 
drug binding ISO
Inferred from Sequence Orthology
more info
 
signal transducer activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
G-protein coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
adenylate cyclase-activating G-protein coupled receptor signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
adenylate cyclase-activating G-protein coupled receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
adenylate cyclase-activating dopamine receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
associative learning IMP
Inferred from Mutant Phenotype
more info
PubMed 
cellular response to catecholamine stimulus ISO
Inferred from Sequence Orthology
more info
 
dopamine receptor signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
dopamine receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
long term synaptic depression IMP
Inferred from Mutant Phenotype
more info
PubMed 
mating behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of NAD(P)H oxidase activity ISO
Inferred from Sequence Orthology
more info
 
negative regulation of blood pressure IGI
Inferred from Genetic Interaction
more info
PubMed 
negative regulation of blood pressure IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of cell migration ISO
Inferred from Sequence Orthology
more info
 
negative regulation of protein kinase activity ISO
Inferred from Sequence Orthology
more info
 
norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of adenylate cyclase activity ISO
Inferred from Sequence Orthology
more info
 
positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
positive regulation of cAMP biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
reactive oxygen species metabolic process ISO
Inferred from Sequence Orthology
more info
 
regulation of female receptivity IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of long-term neuronal synaptic plasticity ISO
Inferred from Sequence Orthology
more info
 
regulation of systemic arterial blood pressure by vasopressin IGI
Inferred from Genetic Interaction
more info
PubMed 
response to amphetamine IGI
Inferred from Genetic Interaction
more info
PubMed 
response to cocaine IMP
Inferred from Mutant Phenotype
more info
PubMed 
sensitization IGI
Inferred from Genetic Interaction
more info
PubMed 
signal transduction IEA
Inferred from Electronic Annotation
more info
 
synaptic transmission IMP
Inferred from Mutant Phenotype
more info
PubMed 
synaptic transmission, dopaminergic ISO
Inferred from Sequence Orthology
more info
 
transmission of nerve impulse IMP
Inferred from Mutant Phenotype
more info
PubMed 
visual learning ISO
Inferred from Sequence Orthology
more info
 
wound healing IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
axon ISO
Inferred from Sequence Orthology
more info
 
brush border membrane IDA
Inferred from Direct Assay
more info
PubMed 
brush border membrane ISO
Inferred from Sequence Orthology
more info
 
dendrite ISO
Inferred from Sequence Orthology
more info
 
dendritic spine ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of plasma membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
neuronal cell body ISO
Inferred from Sequence Orthology
more info
 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
D(1B) dopamine receptor
Names
D(1B) dopamine receptor
dopamine receptor 5
dopamine D5 receptor
d(5) dopamine receptor

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_013503.2NP_038531.1  D(1B) dopamine receptor

    See proteins identical to NP_038531.1

    Status: PROVISIONAL

    Source sequence(s)
    AK045456
    Consensus CDS
    CCDS19255.1
    UniProtKB/TrEMBL
    B2RQS5
    UniProtKB/Swiss-Prot
    Q8BLD9
    Related
    ENSMUSP00000039691, ENSMUST00000041646
    Conserved Domains (2) summary
    pfam00001
    Location:61354
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    pfam10328
    Location:121173
    7TM_GPCR_Srx; Serpentine type 7TM GPCR chemoreceptor Srx

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000071.6 

    Range
    38319509..38322310
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000027.1 

    Range
    35773146..35775947
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)