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    Dmrt1 doublesex and mab-3 related transcription factor 1 [ Mus musculus (house mouse) ]

    Gene ID: 50796, updated on 5-Jan-2016
    Official Symbol
    Dmrt1provided by MGI
    Official Full Name
    doublesex and mab-3 related transcription factor 1provided by MGI
    Primary source
    MGI:MGI:1354733
    See related
    Ensembl:ENSMUSG00000024837; Vega:OTTMUSG00000034256
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Orthologs
    See Dmrt1 in Epigenomics, MapViewer
    Location:
    19; 19 C2-C3
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    105 current GRCm38.p3 (GCF_000001635.23) 19 NC_000085.6 (25505618..25604328)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (25580196..25678818)

    Chromosome 19 - NC_000085.6Genomic Context describing neighboring genes Neighboring gene KN motif and ankyrin repeat domains 1 Neighboring gene predicted gene, 34432 Neighboring gene predicted gene 5249 Neighboring gene doublesex and mab-3 related transcription factor 3 Neighboring gene RIKEN cDNA 2610016A17 gene

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Markers

    Homology

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    Sertoli cell development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Sertoli cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    cell morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    developmental process involved in reproduction IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    germ cell migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    intracellular signal transduction ISO
    Inferred from Sequence Orthology
    more info
     
    male germ cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    male gonad development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    male sex determination IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    male sex differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    multicellular organismal development IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of meiotic nuclear division IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of transcription from RNA polymerase II promoter IDA
    Inferred from Direct Assay
    more info
    PubMed 
    oocyte development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of male gonad development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of meiosis I IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of mitotic nuclear division IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of transcription from RNA polymerase II promoter IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of nodal signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    sex differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    spermatogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    doublesex- and mab-3-related transcription factor 1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_015826.5NP_056641.2  doublesex- and mab-3-related transcription factor 1

      See identical proteins and their annotated locations for NP_056641.2

      Status: VALIDATED

      Source sequence(s)
      AC132140
      Consensus CDS
      CCDS29717.1
      UniProtKB/Swiss-Prot
      Q9QZ59
      Related
      ENSMUSP00000025755, OTTMUSP00000047195, ENSMUST00000025755, OTTMUST00000087042
      Conserved Domains (2) summary
      pfam00751
      Location:70116
      DM; DM DNA binding domain
      pfam12374
      Location:139200
      Dmrt1; Double-sex mab3 related transcription factor 1

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p3 C57BL/6J

    Genomic

    1. NC_000085.6 Reference GRCm38.p3 C57BL/6J

      Range
      25505618..25604328
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011247280.1XP_011245582.1  

      Conserved Domains (2) summary
      pfam00751
      Location:70116
      DM; DM DNA binding domain
      pfam12374
      Location:139200
      Dmrt1; Double-sex mab3 related transcription factor 1
    2. XM_006527181.2XP_006527244.1  

    Alternate Mm_Celera

    Genomic

    1. AC_000041.1 Alternate Mm_Celera

      Range
      26298798..26398802
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)