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Cdk5rap2 CDK5 regulatory subunit associated protein 2 [ Mus musculus (house mouse) ]

Gene ID: 214444, updated on 11-Sep-2014
Official Symbol
Cdk5rap2provided by MGI
Official Full Name
CDK5 regulatory subunit associated protein 2provided by MGI
Primary source
MGI:2384875
Locus tag
RP23-402H11.2
See related
Ensembl:ENSMUSG00000039298; Vega:OTTMUSG00000000307
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
an; mKIAA1633; 2900018K03Rik
See Cdk5rap2 in Epigenomics, MapViewer
Location:
4 C2; 4
Exon count:
39
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 4 NC_000070.6 (70218451..70410467, complement)

Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 3, subunit C pseudogene Neighboring gene 3-hydroxyisobutyrate dehydrogenase pseudogene Neighboring gene CDK5 regulatory subunit-associated protein 2-like Neighboring gene 14-3-3 protein theta-like Neighboring gene multiple EGF-like-domains 9 Neighboring gene uncharacterized LOC102634677

Associated conditions

Description Tests
Hertwig's anemia
GeneReviews: Not available

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (2) 
  • Targeted (1) 
  • Radiation induced (1) 

Markers

Homology

Clone Names

  • MGC38528

Gene Ontology Provided by MGI

Function Evidence Code Pubs
calmodulin binding ISO
Inferred from Sequence Orthology
more info
 
microtubule binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
 
protein complex binding ISO
Inferred from Sequence Orthology
more info
 
protein kinase binding ISO
Inferred from Sequence Orthology
more info
 
transcription regulatory region DNA binding ISO
Inferred from Sequence Orthology
more info
 
tubulin binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
brain development IMP
Inferred from Mutant Phenotype
more info
 
centrosome organization ISO
Inferred from Sequence Orthology
more info
 
chromosome segregation ISO
Inferred from Sequence Orthology
more info
 
establishment of mitotic spindle orientation IMP
Inferred from Mutant Phenotype
more info
 
microtubule bundle formation ISO
Inferred from Sequence Orthology
more info
 
microtubule cytoskeleton organization ISO
Inferred from Sequence Orthology
more info
 
negative regulation of centriole replication IMP
Inferred from Mutant Phenotype
more info
 
negative regulation of neuron differentiation IMP
Inferred from Mutant Phenotype
more info
 
neurogenesis IMP
Inferred from Mutant Phenotype
more info
 
positive regulation of transcription, DNA-templated ISO
Inferred from Sequence Orthology
more info
 
regulation of spindle checkpoint ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
cell IMP
Inferred from Mutant Phenotype
more info
 
cell junction ISO
Inferred from Sequence Orthology
more info
 
centrosome IDA
Inferred from Direct Assay
more info
PubMed 
centrosome ISO
Inferred from Sequence Orthology
more info
 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
extracellular vesicular exosome ISO
Inferred from Sequence Orthology
more info
 
microtubule ISO
Inferred from Sequence Orthology
more info
 
pericentriolar material ISO
Inferred from Sequence Orthology
more info
 
perinuclear region of cytoplasm ISO
Inferred from Sequence Orthology
more info
 
spindle pole ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
CDK5 regulatory subunit-associated protein 2
Names
CDK5 regulatory subunit-associated protein 2
CDK5 activator-binding protein C48

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_145990.3NP_666102.2  CDK5 regulatory subunit-associated protein 2

    See proteins identical to NP_666102.2

    Status: PROVISIONAL

    Source sequence(s)
    AL845502, AL929409
    Consensus CDS
    CCDS38779.1
    UniProtKB/Swiss-Prot
    Q8K389
    Conserved Domains (2) summary
    pfam07989
    Location:58132
    Microtub_assoc; Microtubule associated
    cl02576
    Location:14381560
    B_zip1; basic leucine zipper DNA-binding and multimerization region of GCN4 and related proteins

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000070.6 

    Range
    70218451..70410467
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006537747.1XP_006537810.1  

    Conserved Domains (1) summary
    pfam07989
    Location:58132
    Microtub_assoc; Microtubule associated
  2. XM_006537745.1XP_006537808.1  

    Conserved Domains (1) summary
    pfam07989
    Location:58132
    Microtub_assoc; Microtubule associated
  3. XM_006537746.1XP_006537809.1  

    Related
    ENSMUSP00000119891, OTTMUSP00000000351, ENSMUST00000144099, OTTMUST00000000784
    Conserved Domains (2) summary
    pfam07989
    Location:58132
    Microtub_assoc; Microtubule associated
    cl02576
    Location:14401562
    B_zip1; basic leucine zipper DNA-binding and multimerization region of GCN4 and related proteins
  4. XM_006537744.1XP_006537807.1  

    Conserved Domains (1) summary
    pfam07989
    Location:58132
    Microtub_assoc; Microtubule associated
  5. XM_006537748.1XP_006537811.1  

    Conserved Domains (2) summary
    COG1196
    Location:12641393
    Smc; Chromosome segregation ATPases [Cell division and chromosome partitioning]
    TIGR02169
    Location:15255
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
  6. XM_006537749.1XP_006537812.1  

    Conserved Domains (1) summary
    cl02576
    Location:11651287
    B_zip1; basic leucine zipper DNA-binding and multimerization region of GCN4 and related proteins
  7. XM_006537751.1XP_006537814.1  

    Conserved Domains (1) summary
    cl02576
    Location:824943
    B_zip1; basic leucine zipper DNA-binding and multimerization region of GCN4 and related proteins
  8. XM_006537750.1XP_006537813.1  

    Conserved Domains (1) summary
    pfam07989
    Location:58132
    Microtub_assoc; Microtubule associated

Alternate Mm_Celera

Genomic

  1. AC_000026.1 

    Range
    68823988..69004683
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)