Format

Send to:

Choose Destination

Links from PubMed

    • Showing Current items.

    Cfh complement component factor h [ Mus musculus (house mouse) ]

    Gene ID: 12628, updated on 8-Aug-2016
    Official Symbol
    Cfhprovided by MGI
    Official Full Name
    complement component factor hprovided by MGI
    Primary source
    MGI:MGI:88385
    See related
    Ensembl:ENSMUSG00000026365 Vega:OTTMUSG00000024648
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    NOM; Sas1; Mud-1; Sas-1
    Orthologs
    Location:
    1 61.62 cM; 1 F
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 1 NC_000067.6 (140085855..140183411, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (141982432..142079988, complement)

    Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene complement component factor h pseudogene Neighboring gene complement factor H-related 2 Neighboring gene complement component factor h pseudogene Neighboring gene RuvB-like protein 1 pseudogene Neighboring gene potassium channel, subfamily T, member 2 Neighboring gene RIKEN cDNA 4930590L20 gene Neighboring gene glutathione S-transferase, mu 4 pseudogene

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    complement component C3b binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    heparan sulfate proteoglycan binding ISO
    Inferred from Sequence Orthology
    more info
     
    heparin binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    heparin binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    complement activation, alternative pathway IEA
    Inferred from Electronic Annotation
    more info
     
    immune system process IEA
    Inferred from Electronic Annotation
    more info
     
    innate immune response IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of complement activation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of complement activation ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    blood microparticle ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    extracellular exosome ISO
    Inferred from Sequence Orthology
    more info
     
    extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    extracellular space ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    complement factor H
    Names
    complement factor H related protein 3A4/5G4
    protein beta-1-H
    NP_034018.2

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009888.3NP_034018.2  complement factor H precursor

      Status: VALIDATED

      Source sequence(s)
      BB661130, BC066092
      Consensus CDS
      CCDS48388.1
      UniProtKB/Swiss-Prot
      P06909
      UniProtKB/TrEMBL
      E9Q8I0
      Related
      ENSMUSP00000107607, ENSMUST00000111976
      Conserved Domains (3) summary
      cd00033
      Location:164224
      CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
      PHA02817
      Location:720821
      PHA02817; EEV Host range protein; Provisional
      PHA02927
      Location:19280
      PHA02927; secreted complement-binding protein; Provisional

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000067.6 Reference GRCm38.p4 C57BL/6J

      Range
      140085855..140183411 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)