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    Ppargc1b peroxisome proliferative activated receptor, gamma, coactivator 1 beta [ Mus musculus (house mouse) ]

    Gene ID: 170826, updated on 3-Jul-2016
    Official Symbol
    Ppargc1bprovided by MGI
    Official Full Name
    peroxisome proliferative activated receptor, gamma, coactivator 1 betaprovided by MGI
    Primary source
    MGI:MGI:2444934
    See related
    Ensembl:ENSMUSG00000033871 Vega:OTTMUSG00000024012
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Perc; 4631412G21Rik
    Orthologs
    Location:
    18; 18 E1
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 18 NC_000084.6 (61291445..61401462, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 18 NC_000084.5 (61457790..61560085, complement)

    Chromosome 18 - NC_000084.6Genomic Context describing neighboring genes Neighboring gene solute carrier family 26 (sulfate transporter), member 2 Neighboring gene phosphodiesterase 6A, cGMP-specific, rod, alpha Neighboring gene ribosomal protein S2, pseudogene 10 Neighboring gene uncharacterized LOC108168383 Neighboring gene microRNA 378a Neighboring gene predicted gene 8755 Neighboring gene RIKEN cDNA A530050N04 gene

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    AF-2 domain binding ISO
    Inferred from Sequence Orthology
    more info
     
    RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    RNA polymerase II transcription cofactor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    RNA polymerase II transcription cofactor activity ISO
    Inferred from Sequence Orthology
    more info
     
    estrogen receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    ligand-dependent nuclear receptor transcription coactivator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    ligand-dependent nuclear receptor transcription coactivator activity ISO
    Inferred from Sequence Orthology
    more info
     
    nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    receptor activator activity ISO
    Inferred from Sequence Orthology
    more info
     
    transcription factor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    actin filament organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    bone trabecula formation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cellular response to reactive oxygen species IDA
    Inferred from Direct Assay
    more info
    PubMed 
    intracellular estrogen receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of transcription, DNA-templated IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    ossification IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of alkaline phosphatase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of bone resorption IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of osteoclast differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of phosphorylation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of sequence-specific DNA binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    positive regulation of transcription from RNA polymerase II promoter IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    positive regulation of transcription from RNA polymerase II promoter ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of transcription, DNA-templated IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of transcription, DNA-templated ISO
    Inferred from Sequence Orthology
    more info
     
    transcription from mitochondrial promoter IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    mediator complex ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    peroxisome proliferator-activated receptor gamma coactivator 1-beta
    Names
    ERR ligand 1
    PGC-1-beta
    PGC-1beta
    PGC-1beta/ERRL1
    PPAR gamma coactivator-1beta protein
    PPAR-gamma coactivator 1-beta
    PPARGC-1-beta
    peroxisome proliferator-activated receptor gamma coactivator 1 beta

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_133249.2NP_573512.1  peroxisome proliferator-activated receptor gamma coactivator 1-beta

      See identical proteins and their annotated locations for NP_573512.1

      Status: PROVISIONAL

      Source sequence(s)
      AC116595, AC121903
      Consensus CDS
      CCDS29284.1
      UniProtKB/Swiss-Prot
      Q8VHJ7
      Related
      ENSMUSP00000074771, OTTMUSP00000028482, ENSMUST00000075299, OTTMUST00000058693
      Conserved Domains (2) summary
      smart00360
      Location:894958
      RRM; RNA recognition motif
      cd12356
      Location:891970
      RRM_PPARGC1B; RNA recognition motif in peroxisome proliferator-activated receptor gamma coactivator 1-beta (PGC-1-beta) and similar proteins

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000084.6 Reference GRCm38.p4 C57BL/6J

      Range
      61291445..61401462 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006525698.2XP_006525761.1  

      Conserved Domains (2) summary
      smart00360
      Location:926990
      RRM; RNA recognition motif
      cd12356
      Location:9231002
      RRM_PPARGC1B; RNA recognition motif in peroxisome proliferator-activated receptor gamma coactivator 1-beta (PGC-1-beta) and similar proteins